{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:19:26Z","timestamp":1787836766976,"version":"build-2784847793"},"reference-count":16,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2014,10,1]],"date-time":"2014-10-01T00:00:00Z","timestamp":1412121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Surgical Infections"],"published-print":{"date-parts":[[2014,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>According to the 2002 Surgical Infection Society Guidelines on Antimicrobial Therapy for Intra-abdominal Infections, antimicrobial therapy is not recommended beyond 24 hours for the treatment of postoperative acute or gangrenous appendicitis without perforation. However, clinicians commonly consider gangrenous appendicitis to pose a greater risk of post-operative infectious complications, such as surgical site infections and intra-abdominal abscesses. This study examines the relative risk of post-operative infection between patients with simple and gangrenous appendicitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective review of patients with either non-perforated gangrenous or simple appendicitis from 2010 to 2012 was performed at a large urban teaching hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The rate of post-operative intra-abdominal abscess formation, which was diagnosed on patient readmission to the hospital, was significantly greater in patients with non-perforated gangrenous appendicitis in comparison to those with simple non-perforated appendicitis. Also, patients with non-perforated gangrenous appendicitis received extended courses of post-operative antibiotics, despite SIS recommendations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The role of peri-operative antibiotics for non-perforated gangrenous appendicitis merits further study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/sur.2013.106","type":"journal-article","created":{"date-parts":[[2014,10,14]],"date-time":"2014-10-14T14:50:30Z","timestamp":1413298230000},"page":"517-520","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":24,"title":["Simple Acute Appendicitis versus Non-Perforated Gangrenous Appendicitis: Is There a Difference in the Rate of Post-Operative Infectious Complications?"],"prefix":"10.1177","volume":"15","author":[{"given":"Andrea","family":"Romano","sequence":"first","affiliation":[{"name":"University of Miami\/Miller School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Punam","family":"Parikh","sequence":"additional","affiliation":[{"name":"University of Miami\/Miller School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Byers","sequence":"additional","affiliation":[{"name":"University of Miami\/Miller School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Namias","sequence":"additional","affiliation":[{"name":"University of Miami\/Miller School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,10,14]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a115734"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2004.5.160"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000298158.12101.41"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2008.9951"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1086\/421095"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1086\/505220"},{"key":"e_1_3_2_8_2","first-page":"47","article-title":"Clinical practice guidelines for antimicrobial prophylaxis in surgery","volume":"7","author":"Bratzler DW","year":"2009","unstructured":"Bratzler DW, , Dellinger EP, , Olsen KM, et al. Clinical practice guidelines for antimicrobial prophylaxis in surgery. Treat Guidel Med Lett, 2009; 7:47\u201352.","journal-title":"Treat Guidel Med Lett"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1086\/501620"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198903000-00010"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1086\/649554"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/1749-7922-6-2"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2010.083"},{"key":"e_1_3_2_14_2","first-page":"CD001439","article-title":"Antibiotics versus placebo for prevention of postoperative infection after appendicectomy","volume":"20","author":"Andersen BR","year":"2005","unstructured":"Andersen BR, , Kallehave FL, , Andersen HK. Antibiotics versus placebo for prevention of postoperative infection after appendicectomy. Cochrane Database Syst Rev, 2005; 20:CD001439.","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_3_2_15_2","first-page":"756","article-title":"Role of postoperative antibiotics after appendectomy in non-perforated appendicitis","volume":"22","author":"Hussain MI","year":"2012","unstructured":"Hussain MI, , Alam MK, , Al-Qahatani HH, et al. Role of postoperative antibiotics after appendectomy in non-perforated appendicitis. J Coll Physicians Surg Pak, 2012; 22:756\u2013759.","journal-title":"J Coll Physicians Surg Pak"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2011.08.018"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2005.03397.x"}],"container-title":["Surgical Infections"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/sur.2013.106","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/sur.2013.106","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/sur.2013.106","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T02:18:45Z","timestamp":1777688325000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/sur.2013.106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,1]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,10,1]]}},"alternative-id":["10.1089\/sur.2013.106"],"URL":"https:\/\/doi.org\/10.1089\/sur.2013.106","relation":{},"ISSN":["1096-2964","1557-8674"],"issn-type":[{"value":"1096-2964","type":"print"},{"value":"1557-8674","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,1]]}}}