{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:38:40Z","timestamp":1777934320165,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2014,9,12]],"date-time":"2014-09-12T00:00:00Z","timestamp":1410480000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Surgical Infections"],"published-print":{"date-parts":[[2015,4,1]]},"abstract":"Abstract<\/jats:title>\n \n Background:<\/jats:title>\n This study was conducted to investigate the bacteriology and associated patterns of antibiotic resistance Fournier gangrene.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n Patients with Fournier's gangrene from 2008 to 2012 were identified from the computerized database in a medical center in southern Taiwan. The medical records of all patients with Fournier's gangrene were reviewed retrospectively.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n There were 61 microorganisms, including 60 bacteria and one\n Candida<\/jats:italic>\n spp, isolated from clinical wound specimens from 32 patients. The most common isolates obtained were\n Streptococcus<\/jats:italic>\n spp. (n=12),\n Peptoniphilus<\/jats:italic>\n spp. (n=8),\n Staphylococcus aureus<\/jats:italic>\n (n=7)\n , Escherichia coli<\/jats:italic>\n (n=7)\n , and Klebsiella pneumoniae<\/jats:italic>\n (n=7). Among 21 strains of gram-negative bacilli, five (23.8%) were resistant to fluoroquinolones, and three isolates were resistant to ceftriaxone. Two\n E. coli<\/jats:italic>\n strains produced extended-spectrum beta-lactamase. Four of the seven\n S. aureus<\/jats:italic>\n isolates were methicillin-resistant. Among 15 anaerobic isolates, nine (60%) were resistant to penicillin, and eight (53.3%) were resistant to clindamycin. Four (26.7%) isolates were resistant to metronidazole. The only independent risk factor associated with mortality was inappropriate initial antibiotic treatment (p=0.021).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Antibiotic-resistant bacteria are emerging in the clinical setting of Fournier gangrene. Clinicians should use broad-spectrum antibiotics initially to cover possible antibiotic-resistant bacteria.<\/jats:p>\n <\/jats:sec>","DOI":"10.1089\/sur.2013.118","type":"journal-article","created":{"date-parts":[[2015,1,27]],"date-time":"2015-01-27T10:02:44Z","timestamp":1422352964000},"page":"165-168","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Emergence of Antibiotic-Resistant Bacteria in Patients with Fournier Gangrene"],"prefix":"10.1177","volume":"16","author":[{"given":"Wei-Ting","family":"Lin","sequence":"first","affiliation":[{"name":"Chi Mei Medical Center","place":["Taiwan"]},{"name":"Shu Zen College of Medicine and Management","place":["Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chien-Ming","family":"Chao","sequence":"additional","affiliation":[{"name":"Chi Mei Medical Center","place":["Taiwan"]},{"name":"Min-Hwei College of Health Care Management","place":["Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsin-Lan","family":"Lin","sequence":"additional","affiliation":[{"name":"Chi Mei Medical Center","place":["Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-Chran","family":"Hung","sequence":"additional","affiliation":[{"name":"Chi Mei Medical Center","place":["Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chih-Cheng","family":"Lai","sequence":"additional","affiliation":[{"name":"Chi Mei Medical Center","place":["Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,9,12]]},"reference":[{"key":"e_1_3_2_2_2","first-page":"345","article-title":"Gangrene foudroyante de la verge","volume":"3","author":"Fournier JA","year":"1883","unstructured":"Fournier JA. Gangrene foudroyante de la verge. Semin Med, 1883; 3:345\u2013348.","journal-title":"Semin Med"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.10.041"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.2000.01497.x"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2012.12.041"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.asjsur.2012.04.006"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2005.01204.x"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2006.01.030"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1159\/000335507"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/MAJ.0b013e318142b7b9"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2296-3-20"},{"key":"e_1_3_2_12_2","first-page":"1019","article-title":"Fournier's gangrene: Review of fifteen cases","volume":"63","author":"Basoglu M","year":"1997","unstructured":"Basoglu M, , Gul O, , Yildirgan I, et al. Fournier's gangrene: Review of fifteen cases. Am Surg, 1997; 63:1019\u20131021.","journal-title":"Am Surg"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02237442"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2009.08.090"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(00)00527-6"},{"key":"e_1_3_2_16_2","first-page":"532","article-title":"Fournier's gangrene: Our experience in 5 years, bibliographic review and assessment of the Fournier's gangrene severity index","volume":"65","author":"Morua AG","year":"2009","unstructured":"Morua AG, , Lopez JA, , Garcia JD, et al. Fournier's gangrene: Our experience in 5 years, bibliographic review and assessment of the Fournier's gangrene severity index. Arch Esp Urol, 2009; 65:532\u2013540.","journal-title":"Arch Esp Urol"}],"container-title":["Surgical Infections"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/sur.2013.118","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/sur.2013.118","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/sur.2013.118","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T02:18:48Z","timestamp":1777688328000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/sur.2013.118"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9,12]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,4,1]]}},"alternative-id":["10.1089\/sur.2013.118"],"URL":"https:\/\/doi.org\/10.1089\/sur.2013.118","relation":{},"ISSN":["1096-2964","1557-8674"],"issn-type":[{"value":"1096-2964","type":"print"},{"value":"1557-8674","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,12]]}}}