{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:43:47Z","timestamp":1777934627308,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T00:00:00Z","timestamp":1664409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Surgical Infections"],"published-print":{"date-parts":[[2022,10,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Ileocolic intussusception is a common gastrointestinal emergency that occurs in infancy. Many cases are caused by anatomic lead points, such as hypertrophied Peyer's patches. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, which causes coronavirus disease 2019 (COVID-19), commonly presents with respiratory symptoms, however, its relation to intussusception remains unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Two cases are reported as well as a review of pertinent English-language literature on the topic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>We present two cases of intussusception in COVID-19\u2013positive patients, including the first known case of a lead point with tissue polymerase chain reaction (PCR) confirming COVID-19 positivity, and compare these findings to a review of the recent literature. Intussusception in COVID-19\u2013positive patients is becoming more prevalent and more often requires operative treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>We offer evidence that intussusception can be the presenting symptom in the absence of COVID-19\u2013related respiratory symptoms. There also seems to be a trend toward the need for operative intervention compared with COVID-19\u2013negative intussusception. The presence of SARS-CoV-2 can be confirmed via PCR in specific lead points (lymph nodes), directly causing the intussusception.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Providers should have a low threshold to suspect and diagnose intussusception as operative treatment is more readily used in COVID-19\u2013positive pediatric patients with gastrointestinal symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/sur.2022.139","type":"journal-article","created":{"date-parts":[[2022,8,19]],"date-time":"2022-08-19T09:45:21Z","timestamp":1660902321000},"page":"712-716","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["COVID-19\u2013Related Intussusception: A Case Series and Review of the Literature"],"prefix":"10.1177","volume":"23","author":[{"given":"Tyler","family":"Leiva","sequence":"first","affiliation":[{"name":"Division of Pediatric Surgery, Oklahoma Children's Hospital, Oklahoma City, Oklahoma, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Luschen","sequence":"additional","affiliation":[{"name":"School of Medicine, The University of Oklahoma Health Science Center, Oklahoma City, Oklahoma, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongxin","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Pathology, The University of Oklahoma Health Science Center, Oklahoma City, Oklahoma, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heather","family":"Liebe","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Oklahoma Children's Hospital, Oklahoma City, Oklahoma, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alena","family":"Golubkova","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Oklahoma Children's Hospital, Oklahoma City, Oklahoma, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine J.","family":"Hunter","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, Oklahoma Children's Hospital, Oklahoma City, Oklahoma, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,9,29]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-009-1178-9"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31824213b1"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-018-4259-9"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.15.15659"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000002860"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2016-1082"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/PEC.0000000000000893"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-019-04488-z"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.47102\/annals-acadmedsg.V31N1p81"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2005.12.047"},{"issue":"6","key":"e_1_3_4_12_2","first-page":"1","article-title":"COVID-19: The impact on pediatric emergency care","volume":"17","author":"Walker DM","year":"2020","unstructured":"Walker DM, , Tolentino VR. 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