{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:43:56Z","timestamp":1777934636283,"version":"3.51.4"},"reference-count":40,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Surgical Infections"],"published-print":{"date-parts":[[2022,8,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>We sought to examine health-care\u2013associated infections (HAIs) among patients undergoing an appendectomy at academic medical centers (AMCs) and non-AMCs during the coronavirus disease 2019 (COVID-19) peri-pandemic. We hypothesized that AMCs would have higher rates of post-operative HAIs during the first wave of the pandemic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>We performed a post hoc analysis of a prospective, observational, multi-center study of patients aged &gt;18 years who underwent an appendectomy for acute appendicitis before (pre-CoV), during (CoV), and after pandemic restrictions were lifted (post-CoV). Patients were grouped according to hospital type (AMC vs. non-AMC). Our primary outcome was the incidence of post-operative HAIs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>There were 1,003 patients; 69.5% (n\u2009=\u2009697) were treated at AMCs and 30.5% (n\u2009=\u2009306) at non-AMCs. Patients at AMCs had greater rates of concomitant COVID-19 infections (5.5% vs. 0.7%; p\u2009&lt;\u20090.0001) and worse operative appendicitis severity (p\u2009=\u20090.01). Greater rates of HAIs were seen at AMCs compared with non-AMCs (4.9% vs. 2%; p\u2009=\u20090.03). Surgical site infections were the most common HAI and occurred more often at AMCs (4.3% vs. 1.6%; p\u2009=\u20090.04). Only during CoV were there more HAIs at AMCs (5.1% vs. 0.3%; p\u2009=\u20090.02). Undergoing surgery at an AMC during CoV was a risk factor for HAIs (adjusted odds ratio [aOR], 8.55; 95% confidence interval [CI], 1.03\u201371.03; p\u2009=\u20090.04).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>During the COVID-19 pandemic, appendectomies performed at AMCs were an independent risk factor for post-operative HAIs. Our findings stress the importance of adherence to standard infection prevention efforts during future healthcare crises.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/sur.2022.148","type":"journal-article","created":{"date-parts":[[2022,8,2]],"date-time":"2022-08-02T14:11:30Z","timestamp":1659449490000},"page":"538-544","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Academic Medical Centers Experienced Higher Rates of Post-Operative Health-Care\u2013Associated Infections during the COVID-19 Pandemic: A Post Hoc Analysis of an Eastern Association for the Surgery of Trauma Multicenter Trial"],"prefix":"10.1177","volume":"23","author":[{"given":"Brett M.","family":"Tracy","sequence":"first","affiliation":[{"name":"Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carrie L.","family":"Valdez","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon","family":"Crowley","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Alabama at Birmingham Medical Center, Birmingham, Alabama, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sirivan","family":"Seng","sequence":"additional","affiliation":[{"name":"Department of Surgery, Crozer Chester Medical Center, Chester, Pennsylvania, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asanthi","family":"Ratnasekera","sequence":"additional","affiliation":[{"name":"Department of Surgery, Crozer Chester Medical Center, Chester, Pennsylvania, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Courtney M.","family":"Collins","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bishwajit","family":"Bhattacharya","sequence":"additional","affiliation":[{"name":"Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rick","family":"O'Connor","sequence":"additional","affiliation":[{"name":"Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"Sharp","sequence":"additional","affiliation":[{"name":"Department of Surgery, St. Joseph Mercy Ann Arbor Hospital, Ypsilanti, Michigan, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rondi B.","family":"Gelbard","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Alabama at Birmingham Medical Center, Birmingham, Alabama, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,8,1]]},"reference":[{"key":"e_1_3_5_2_2","unstructured":"Centers for Disease Control and Prevention. 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