{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T22:44:23Z","timestamp":1777934663173,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Surgical Infections"],"published-print":{"date-parts":[[2024,9,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The prophylactic use of antibiotics in parotid region surgery continues to be a subject of debate. The aim of this study is to elucidate the impact of antibiotic prophylaxis on surgical site infections (SSIs) in parotid region surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>Patients who received antibiotic prophylaxis during the peri-operative period were designated as group 1, whereas those who did not were categorized into group 2. Group 1 cases were further subdivided into three subgroups based on different antibiotic usage patterns. Patient individual information was collected. Clinical data such as surgical duration, post-operative hospital stay, incision infection status, and antibiotic usage were recorded. All data were compared and analyzed among different groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 357 patients were included in the study, with no statistically significant differences in baseline characteristics. Pre-operative American Society of Anesthesiologists scores did not significantly differ between groups (p = 0.151), but there was a significant distinction in National Nosocomial Infection Surveillance (NNIS) index values (p = 0.044). Furthermore, surgical duration (p = 0.001) and pathology types (p = 0.016) differed significantly. The post-operative hospital stay in group 1 was longer than that in group 2 (p &lt; 0.01). The post-operative SSI rate in group 1 was lower than that in group 2 without statistical significance (2.55% vs. 5.59%, p = 0.141). The logistic regression analysis showed that malignant tumors, longer surgical durations, and higher NNIS index scores correlated positively with post-operative SSI rates. Meanwhile, compared with non-use, all three different antibiotic use modes correlated negatively with SSI occurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Antibiotic prophylaxis in parotid gland surgery shows no significant reduction in SSI occurrence. If there is a compelling reason to administer prophylactic antibiotics, pre-operative single dose may be a relatively feasible measure for preventing SSIs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/sur.2024.054","type":"journal-article","created":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T04:56:14Z","timestamp":1719982574000},"page":"521-526","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Is Antibiotic Prophylaxis Reasonable in Parotid Surgery? Retrospective Analysis of Surgical Site Infection"],"prefix":"10.1177","volume":"25","author":[{"given":"Dong","family":"Wei","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuping","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Stomatology, People\u2019s Hospital of Changshan, Quzhou, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7231-6387","authenticated-orcid":false,"given":"Ling","family":"Bi","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,9,10]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(10)80477-X"},{"issue":"1","key":"e_1_3_7_3_2","first-page":"E1876","article-title":"Role of perioperative antibiotic treatment in parotid gland surgery","volume":"38","author":"Shkedy Y","year":"2016","unstructured":"Shkedy Y, , Alkan U, , Roman BR, et al. Role of perioperative antibiotic treatment in parotid gland surgery. Head Neck, 2016; 38(Suppl 1):E1876\u2013E1880; doi: 10.1002\/hed.24339","journal-title":"Head Neck"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/coa.13753"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.14639\/0392-100X-1768"},{"key":"e_1_3_7_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(91)90361-Z"},{"key":"e_1_3_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2023.09.005"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-019-01303-8"},{"issue":"5","key":"e_1_3_7_9_2","first-page":"e24979","article-title":"The ideal time to administer pre-operative antibiotics: Current and future practices","volume":"14","author":"Baseel D","year":"2022","unstructured":"Baseel D, , Kim J, , Mohammed S, et al. The ideal time to administer pre-operative antibiotics: Current and future practices. Cureus Journal of Medical Science, 2022; 14(5):e24979; doi: 10.7759\/cureus.24979","journal-title":"Cureus Journal of Medical Science"},{"issue":"10","key":"e_1_3_7_10_2","article-title":"Antibiotic prophylaxis in surgery: Current insights and future directions for surgical site infection prevention","volume":"15","author":"Dhole S","year":"2023","unstructured":"Dhole S, , Mahakalkar C, , Kshirsagar S, et al. Antibiotic prophylaxis in surgery: Current insights and future directions for surgical site infection prevention. Cureus, 2023; 15(10):e47858-e47858; doi: 10.7759\/cureus.47858","journal-title":"Cureus"},{"key":"e_1_3_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mpsur.2012.10.001"},{"key":"e_1_3_7_12_2","volume-title":"Antibiotic Prophylaxis for Surgical Procedures","author":"In","year":"2010","unstructured":"In. Antibiotic Prophylaxis for Surgical Procedures: A Systematic Review. Stockholm; 2010."},{"key":"e_1_3_7_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkg460"},{"key":"e_1_3_7_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-008-0588-x"},{"key":"e_1_3_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coms.2021.08.015"},{"key":"e_1_3_7_16_2","doi-asserted-by":"publisher","DOI":"10.1080\/19424396.1997.12221601"},{"key":"e_1_3_7_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2020.09.020"},{"issue":"5","key":"e_1_3_7_18_2","article-title":"Six long-standing questions about antibiotic prophylaxis in surgery","volume":"12","author":"Sartelli M","year":"2023","unstructured":"Sartelli M, , Boermeester MA, , Cainzos M, et al. Six long-standing questions about antibiotic prophylaxis in surgery. 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