{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T03:35:33Z","timestamp":1782444933736,"version":"3.54.5"},"reference-count":45,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T00:00:00Z","timestamp":1753833600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Surgical Infections"],"published-print":{"date-parts":[[2025,8,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Abdominal operation is common as are surgical site infections (SSIs). Triclosan (polychlorophenoxyphenol) is an antimicrobial antiseptic used in a variety of consumer products, including suture. The Surgical Infection Society\u2019s Therapeutics and Guidelines Committee convened to perform a systematic review and develop pragmatic recommendations for use of triclosan-coated suture in prevention of SSI after an abdominal surgical procedure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A research librarian designed and performed searches of three bibliographic databases: PubMed, Embase, and Web of Science. Methodology for this practice management guideline conformed to Reporting Items for practice Guidelines in HealThcare Working Group standards. Covidence was used for study selection and quality and certainty of published evidence was evaluated using GRADE. The clinical question assessed was: \u201cFor adult patients undergoing abdominal surgery, does triclosan-coated suture vs. non-triclosan-coated suture reduce the risk of post-operative SSI?\u201d<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 3,616 studies were identified, with 30 studies involving 97,807 patients informing the clinical question response. Among included studies, 13 (43%) were randomized controlled trials (RCTs) and 17 (57%) were meta-analyses. Seventeen (57%) studies comprising 67,445 (69%) patients demonstrated reduction in SSI, with 13 (43%) studies comprising 30,362 (31%) patients demonstrating no benefit. Estimated cumulative adjusted absolute risk reduction associated with triclosan-coated sutures, among studies demonstrating benefit, was 3.2% (standard deviation \u00b16.2%). Overall quality of evidence was high. We recommend triclosan-coated suture for incision closure after an abdominal operation to reduce risk of SSI\n                      <jats:italic toggle=\"yes\">(Grade 1A)<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Higher-level evidence suggests a small but significant benefit for triclosan-coated suture in reducing SSI risk following an abdominal surgical procedure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/sur.2025.011","type":"journal-article","created":{"date-parts":[[2025,4,26]],"date-time":"2025-04-26T04:07:09Z","timestamp":1745640429000},"page":"441-450","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Surgical Infection Society Guidelines for Use of Antimicrobial Agent-Coated Suture to Reduce the Risk of Surgical Site Infection after Abdominal Operation"],"prefix":"10.1177","volume":"26","author":[{"given":"Joseph D.","family":"Forrester","sequence":"first","affiliation":[{"name":"Division of General Surgery, Department of Surgery, Stanford University, Stanford, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anu","family":"Seshadri","sequence":"additional","affiliation":[{"name":"Division of Acute Care Surgery, Trauma, and Surgical Critical Care, Beth Isreal Deaconess Medical Center, Boston, Massachusetts, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nimitt","family":"Patel","sequence":"additional","affiliation":[{"name":"Division of Trauma, Critical Care, Burn and Emergency General Surgery, MetroHealth Medical Center, Case Western Reserve University, Cleveland, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0616-4634","authenticated-orcid":false,"given":"Najiha","family":"Farooqi","sequence":"additional","affiliation":[{"name":"Division of General Surgery, Department of Surgery, Stanford University, Stanford, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janice","family":"Lester","sequence":"additional","affiliation":[{"name":"Health Science Library, Long Island Jewish Medical Center, Northwell Health, New Hyde Park, New York, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phil","family":"Barie","sequence":"additional","affiliation":[{"name":"Departments of Surgery and Medicine, Weill Cornell Medicine, East Northport, New York, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jared","family":"Huston","sequence":"additional","affiliation":[{"name":"Division of Trauma and Acute Care Surgery, Department of Surgery, Zucker School of Medicine at Hofstra\/Northwell, New Hyde Park, New York, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Therapeutics and Guidelines Committee of the Surgical Infection Society","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,7,30]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2017.01.001"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2022.08.006"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/PTS.0000000000000845"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1086\/662016"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)01548-8"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2017.0904"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/bjs\/znac196"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1080\/10937404.2017.1399306"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1080\/1364557032000119616"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.7326\/M16-1565"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39489.470347.AD"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39490.551019.BE"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2010.04.026"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2012.03.013"},{"issue":"6","key":"e_1_3_5_16_2","first-page":"770","article-title":"Efficacy of antimicrobial coating suture coated polyglactin 910 with tricosan (Vicryl plus) compared with polyglactin 910 (Vicryl) in reduced surgical site infection of appendicitis, double blind randomized control trial, preliminary safety report","volume":"92","author":"Mingmalairak C","year":"2009","unstructured":"Mingmalairak C, , Ungbhakorn P, , Paocharoen V. 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