{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:55:49Z","timestamp":1791330949406,"version":"4.3.1"},"reference-count":106,"publisher":"SAGE Publications","issue":"9-10","license":[{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.liebertpub.com\/nv\/resources-tools\/text-and-data-mining-policy\/121\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tissue Engineering Part A"],"published-print":{"date-parts":[[2015,5]]},"DOI":"10.1089\/ten.tea.2014.0474","type":"journal-article","created":{"date-parts":[[2015,1,8]],"date-time":"2015-01-08T08:27:25Z","timestamp":1420705645000},"page":"1483-1494","source":"Crossref","is-referenced-by-count":31,"title":["Heparin Binding\u2013Epidermal Growth Factor-Like Growth Factor for the Regeneration of Chronic Tympanic Membrane Perforations in Mice"],"prefix":"10.1177","volume":"21","author":[{"given":"Peter Luke","family":"Santa Maria","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Stanford University, Stanford, California."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sungwoo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Stanford University, Stanford, California."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasin Kursad","family":"Varsak","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Stanford University, Stanford, California."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunzhi Peter","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery, Stanford University, Stanford, California."},{"name":"Department of Materials Science and Engineering, Stanford University, Stanford, California."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"B1","unstructured":"AcuinJ. Chronic Suppurative Otitis Media: Burden of Illness and Management Options. Switzerland: World Health Organisation, 2004."},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-007-0570-z"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215106000697"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0036226"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e318245cb51"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24221"},{"key":"B7","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/S0030-6665(20)30467-9","volume":"28","author":"Gladstone H.B.","year":"1995","journal-title":"Otolaryngol Clin North Am"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2012.09.022"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-011-1627-6"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(96)70008-6"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200308000-00016"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3181c34f01"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31822e0e53"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0709(00)85017-6"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31822e96bc"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(99)70122-1"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.3109\/00016488709102840"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1988.01860240085029"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-475X.2008.00375.x"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(95)70071-4"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2012.01.009"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.31909"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tea.2013.0351"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1002\/lary.20998"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200209000-00024"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.151.2.209"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1007\/s10162-007-0092-9"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.02346"},{"key":"B29","first-page":"462","volume":"21","author":"El-Seifi A.","year":"2000","journal-title":"Am J Otol"},{"key":"B30","first-page":"707","volume":"31","author":"Fagan P.","year":"2002","journal-title":"Aust Fam Physician"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-475X.1994.20305.x"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1002\/lary.22150"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-475X.2007.00251.x"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200101000-00016"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2005.08.021"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.3109\/00016488409122883"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2273.1997.00006.x"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199603000-00020"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1159\/000276181"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1177\/000348948909801002"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.3109\/00016488409122879"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1080\/00016480600749994"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1080\/00016480410022804"},{"key":"B44","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1177\/00034894800890S381","volume":"89","author":"Lewis D.M.","year":"1980","journal-title":"Ann Otol Rhinol Laryngol Suppl"},{"key":"B45","first-page":"1","volume":"93","author":"Watanabe N.","year":"1982","journal-title":"Ann Otol Rhinol Laryngol Suppl"},{"key":"B46","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1128\/IAI.67.4.1943-1946.1999","volume":"67","author":"Sato K.","year":"1999","journal-title":"Infect Immun"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1177\/000348940911800410"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/134.6.595"},{"key":"B49","first-page":"9","volume":"93","author":"Watanabe N.","year":"1982","journal-title":"Ann Otol Rhinol Laryngol Suppl"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.033175-0"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2011.07.026"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2012.02.008"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/136.Supplement.S191"},{"key":"B54","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1128\/iai.30.2.445-450.1980","volume":"30","author":"Giebink G.S.","year":"1980","journal-title":"Infect Immun"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200305000-00002"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-5955(97)00008-7"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1007\/BF00179947"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0463.2003.1111012.x"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2006.05.012"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2012.02.002"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200111000-00010"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2002.17.2.230"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1984.00800330011002"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1177\/000348940311200614"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200311000-00036"},{"key":"B66","first-page":"661","volume":"41","author":"Raustyte G.","year":"2005","journal-title":"Medicina"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200208000-00027"},{"key":"B68","first-page":"144","volume":"457","author":"Hermansson A.","year":"1989","journal-title":"Acta Otolaryngol Suppl"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1007\/BF00181964"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1016\/S0264-410X(03)00501-2"},{"key":"B71","doi-asserted-by":"crossref","first-page":"6098","DOI":"10.1128\/IAI.67.11.6098-6103.1999","volume":"67","author":"van der Ven L.T.","year":"1999","journal-title":"Infect Immun"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0463.2006.apm_297.x"},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0709(88)80013-9"},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.7.4024-4031.2000"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.1006\/mpat.2000.0414"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200406000-00014"},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.1177\/000348949810700608"},{"key":"B78","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(01)00540-7"},{"key":"B79","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2005.03.033"},{"key":"B80","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2006.12.019"},{"key":"B81","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2002.124935"},{"key":"B82","doi-asserted-by":"publisher","DOI":"10.1177\/0194599813479772"},{"key":"B83","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2005.03.026"},{"key":"B84","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.5.1746"},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2014.03.004"},{"key":"B86","doi-asserted-by":"crossref","first-page":"6205","DOI":"10.1016\/S0021-9258(18)42682-8","volume":"267","author":"Higashiyama S.","year":"1992","journal-title":"J Biol Chem"},{"key":"B87","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/16.6.1268"},{"key":"B88","doi-asserted-by":"publisher","DOI":"10.1126\/science.1840698"},{"key":"B89","doi-asserted-by":"publisher","DOI":"10.1038\/387509a0"},{"key":"B90","doi-asserted-by":"publisher","DOI":"10.1038\/387512a0"},{"key":"B91","doi-asserted-by":"publisher","DOI":"10.1126\/science.8456283"},{"key":"B92","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200112026"},{"key":"B93","doi-asserted-by":"publisher","DOI":"10.1038\/nm0102-35"},{"key":"B94","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/17.24.7260"},{"key":"B95","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.48.30858"},{"key":"B96","doi-asserted-by":"crossref","first-page":"2541","DOI":"10.1016\/S0021-9258(17)41979-X","volume":"269","author":"Thompson S.A.","year":"1994","journal-title":"J Biol Chem"},{"key":"B97","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.78"},{"key":"B98","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M506069200"},{"key":"B99","doi-asserted-by":"publisher","DOI":"10.1126\/science.282.5392.1281"},{"key":"B100","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2006.11.074"},{"key":"B101","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200307137"},{"key":"B102","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-007-9392-3"},{"key":"B103","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.33118"},{"key":"B104","doi-asserted-by":"publisher","DOI":"10.2147\/nano.2006.1.2.181"},{"key":"B105","doi-asserted-by":"publisher","DOI":"10.1016\/j.carres.2003.09.013"},{"key":"B106","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2008.0327"}],"container-title":["Tissue Engineering Part A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.liebertpub.com\/doi\/full-xml\/10.1089\/ten.tea.2014.0474","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.liebertpub.com\/doi\/pdf\/10.1089\/ten.tea.2014.0474","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T04:44:15Z","timestamp":1777697055000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/ten.tea.2014.0474"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5]]},"references-count":106,"journal-issue":{"issue":"9-10","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["10.1089\/ten.tea.2014.0474"],"URL":"https:\/\/doi.org\/10.1089\/ten.tea.2014.0474","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.725328912.793522750","asserted-by":"object"}]},"ISSN":["1937-3341","1937-335X"],"issn-type":[{"value":"1937-3341","type":"print"},{"value":"1937-335X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5]]}}}