{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T06:23:49Z","timestamp":1790403829926,"version":"4.1.0"},"reference-count":41,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.liebertpub.com\/nv\/resources-tools\/text-and-data-mining-policy\/121\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tissue Engineering Part C: Methods"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1089\/ten.tec.2017.0109","type":"journal-article","created":{"date-parts":[[2017,7,27]],"date-time":"2017-07-27T00:22:23Z","timestamp":1501114943000},"page":"745-753","source":"Crossref","is-referenced-by-count":31,"title":["Age-Dependent Subchondral Bone Remodeling and Cartilage Repair in a Minipig Defect Model"],"prefix":"10.1177","volume":"23","author":[{"given":"Christian G.","family":"Pfeifer","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania."},{"name":"Translational Musculoskeletal Research Center, Philadelphia VA Medical Center, Philadelphia, Pennsylvania."},{"name":"Department of Trauma Surgery, Regensburg University Medical Center, Regensburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew B.","family":"Fisher","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania."},{"name":"Translational Musculoskeletal Research Center, Philadelphia VA Medical Center, Philadelphia, Pennsylvania."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishal","family":"Saxena","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania."},{"name":"Translational Musculoskeletal Research Center, Philadelphia VA Medical Center, Philadelphia, Pennsylvania."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minwook","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania."},{"name":"Translational Musculoskeletal Research Center, Philadelphia VA Medical Center, Philadelphia, Pennsylvania."},{"name":"Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth A.","family":"Henning","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania."},{"name":"Translational Musculoskeletal Research Center, Philadelphia VA Medical Center, Philadelphia, Pennsylvania."},{"name":"Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Steinberg","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania."},{"name":"Translational Musculoskeletal Research Center, Philadelphia VA Medical Center, Philadelphia, Pennsylvania."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George R.","family":"Dodge","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania."},{"name":"Translational Musculoskeletal Research Center, Philadelphia VA Medical Center, Philadelphia, Pennsylvania."},{"name":"Collaborative Research Partner (CRP), Acute Cartilage Injury (ACI) Program of the AO Foundation, Davos, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert L.","family":"Mauck","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania."},{"name":"Translational Musculoskeletal Research Center, Philadelphia VA Medical Center, Philadelphia, Pennsylvania."},{"name":"Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania."},{"name":"Collaborative Research Partner (CRP), Acute Cartilage Injury (ACI) Program of the AO Foundation, Davos, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546516645514"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546509350694"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1177\/0363546508330137"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2005.04.003"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1177\/0363546511399382"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2006.05.003"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1177\/0363546509358266"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199710000-00001"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-002-2153-8"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tea.2014.0384"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1177\/0363546511403282"},{"key":"B12","doi-asserted-by":"crossref","first-page":"290","DOI":"10.2460\/ajvr.1989.50.02.290","volume":"50","author":"Shamis L.D.","year":"1989","journal-title":"Am J Vet Res"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2005.04.001"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-010-1072-x"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2006.09.012"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1474-9726.2010.00633.x"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2012.05.010"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1177\/0363546509359068"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.22203\/eCM.v025a21"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1002\/jor.20775"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1177\/0363546509350984"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1007\/s11914-011-0067-y"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2006.04.003"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tea.2015.0150"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1177\/1947603515623030"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-12-49"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2012.06.008"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4636(199701)34:1<63::AID-JBM9>3.0.CO;2-L"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1107966108"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.70.1.30"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199304000-00009"},{"key":"B32","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1302\/0301-620X.73B1.1991776","volume":"73","author":"Shahgaldi B.F.","year":"1991","journal-title":"J Bone Joint Surg Br"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200101000-00008"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1053\/jvet.1999.0242"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1002\/term.127"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1002\/jor.22740"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tea.2013.0013"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1016\/S0736-0266(00)90015-9"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1053\/joca.1998.0180"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1016\/S1063-4584(03)00164-X"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/16830245"}],"container-title":["Tissue Engineering Part C: Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.liebertpub.com\/doi\/full-xml\/10.1089\/ten.tec.2017.0109","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.liebertpub.com\/doi\/pdf\/10.1089\/ten.tec.2017.0109","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T05:14:50Z","timestamp":1777698890000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/ten.tec.2017.0109"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":41,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1089\/ten.tec.2017.0109"],"URL":"https:\/\/doi.org\/10.1089\/ten.tec.2017.0109","relation":{},"ISSN":["1937-3384","1937-3392"],"issn-type":[{"value":"1937-3384","type":"print"},{"value":"1937-3392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11]]}}}