{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T23:13:03Z","timestamp":1780701183012,"version":"3.54.1"},"reference-count":31,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Hypothermia and Temperature Management"],"published-print":{"date-parts":[[2024,12,1]]},"abstract":"<jats:p>\n                    The relationship between body temperature changes and prognosis in patients with acute respiratory distress syndrome (ARDS) remains inconclusive. Our study aimed to investigate the clinical value of body temperature in the management of ARDS. Data from the Medical Information Mart for Intensive Care III database were collected. Adult patients with ARDS were enrolled and further grouped based on their temperature values in the intensive care unit. Both the maximum (temperature\n                    <jats:sub>max<\/jats:sub>\n                    ) and minimum (temperature\n                    <jats:sub>min<\/jats:sub>\n                    ) temperatures were used. The primary outcome was 28-day mortality rate. Polynomial regression, subgroup analysis, and logistic regression analysis were performed in the final analysis. A total of 3922 patients with ARDS were enrolled. There was a U-shaped relationship between 28-day mortality and body temperature. For patients with infection, the elevated temperature\n                    <jats:sub>max<\/jats:sub>\n                    (\u226537.0\u00b0C) was associated with decreased mortality, with an odds ratio ranging from 0.39 to 0.49, using temperature\n                    <jats:sub>max<\/jats:sub>\n                    from 36.5\u00b0C to 36.9\u00b0C as reference. For patients without infection, a similar tendency was observed, but the protective effect was lost at extremely high temperatures (\u226538.0\u00b0C,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009&lt;\u20090.05). Elevated temperature\n                    <jats:sub>min<\/jats:sub>\n                    (\u226537.0\u00b0C) and decreased temperature\n                    <jats:sub>min<\/jats:sub>\n                    (&lt;35.0\u00b0C) were associated with increased mortality, using the temperature\n                    <jats:sub>min<\/jats:sub>\n                    from 36.0\u00b0C to 36.9\u00b0C as a reference. Hypothermia was associated with increased mortality in patients with ARDS, while the effect of hyperthermia (\u226537.0\u00b0C) on the mortality of patients with ARDS was not fully consistent in the infection and noninfection subgroups. Short-term and transient temperatures above 37.0\u00b0C would be beneficial to patients with ARDS, but extreme hyperthermia and persistent temperatures above 37.0\u00b0C should be avoided.\n                  <\/jats:p>","DOI":"10.1089\/ther.2023.0047","type":"journal-article","created":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T12:50:56Z","timestamp":1700225456000},"page":"258-268","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Association Between Temperature During Intensive Care Unit and Mortality in Patients With Acute Respiratory Distress Syndrome"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6051-5274","authenticated-orcid":false,"given":"Yipeng","family":"Fang","sequence":"first","affiliation":[{"name":"Laboratory of Molecular Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China."},{"name":"Laboratory of Medical Molecular Imaging, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China."},{"name":"Shantou University Medical College, Shantou, Guangdong, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9475-3908","authenticated-orcid":false,"given":"Yunfei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Tianjin Hospital, Tianjin, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5978-5031","authenticated-orcid":false,"given":"Xianxi","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7742-1175","authenticated-orcid":false,"given":"Qian","family":"Liu","sequence":"additional","affiliation":[{"name":"Shantou University Medical College, Shantou, Guangdong, China."},{"name":"Department of Cardiology, The Affiliated Hospital of Binzhou Medical University, Binzhou, Shandong, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueyang","family":"Li","sequence":"additional","affiliation":[{"name":"Shantou University Medical College, Shantou, Guangdong, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenxi","family":"Jia","sequence":"additional","affiliation":[{"name":"Shantou University Medical College, Shantou, Guangdong, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingbin","family":"He","sequence":"additional","affiliation":[{"name":"Shantou University Medical College, Shantou, Guangdong, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6530-7781","authenticated-orcid":false,"given":"Chunhong","family":"Ren","sequence":"additional","affiliation":[{"name":"International Medical Service Center, The First Affiliated hospital of Shantou University Medical College, Shantou, Guangdong, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5113-1420","authenticated-orcid":false,"given":"Xin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Cardiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China."},{"name":"Laboratory of Medical Molecular Imaging, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China."},{"name":"Shantou University Medical College, Shantou, Guangdong, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,12,16]]},"reference":[{"key":"e_1_3_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200107000-00002"},{"key":"e_1_3_7_3_1","first-page":"2526","article-title":"Acute respiratory distress syndrome: the Berlin Definition","volume":"307","author":"ARDS Definition Task Force","year":"2012","unstructured":"ARDS Definition Task Force, , Ranieri VM, , Rubenfeld GD, et al. Acute respiratory distress syndrome: the Berlin Definition. 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Prediction model for critically ill patients with acute respiratory distress syndrome. 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