{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T12:54:50Z","timestamp":1781873690260,"version":"3.54.5"},"reference-count":18,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T00:00:00Z","timestamp":1739232000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Hypothermia and Temperature Management"],"published-print":{"date-parts":[[2026,3,1]]},"abstract":"<jats:p>Despite growing evidence supporting the efficacy of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for accidental hypothermia (AH), few studies have assessed its real-world application. We aimed to describe the use and outcomes of VA-ECMO in AH patients using data from a multicenter registry. This retrospective study included adult AH patients from the Japanese accidental hypothermia network registry (J-Point registry) between April 2011 and March 2016. We analyzed patient characteristics, in-hospital data, VA-ECMO indications, and clinical outcomes for those who received VA-ECMO. Of the 537 patients in this registry, 22 received VA-ECMO, with a median age of 80 years. Severe AH was present in 18 patients, and 10 experienced cardiac arrest (CA) on hospital arrival. VA-ECMO was indicated for CA on hospital arrival (10 patients), CA after hospital arrival (5), hemodynamic instability (5), and severe hypothermia (1), with 1 case having an unclear indication. Rewarming was successful in 18 patients, and 9 survived. Survival was higher among those with CA on hospital arrival (5\/10) compared with those who developed CA after hospital arrival (1\/5). This study highlights the clinical application and outcomes of VA-ECMO for AH patients using multicenter registry data. Among the 22 patients who received VA-ECMO, 9 survived. Patients with CA on hospital arrival showed better survival compared with those who developed CA after arrival, emphasizing the importance of timely VA-ECMO initiation. Further research is warranted to refine patient selection, optimize initiation timing, and evaluate long-term outcomes.<\/jats:p>","DOI":"10.1089\/ther.2024.0061","type":"journal-article","created":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T11:06:26Z","timestamp":1739271986000},"page":"16-23","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Characteristics and Outcomes of Veno-Arterial Extracorporeal Membrane Oxygenation in Accidental Hypothermia: A Multicenter Study in Japan"],"prefix":"10.1177","volume":"16","author":[{"given":"Tadaharu","family":"Shiozumi","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Miyamoto","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachiko","family":"Morita","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Senri Critical Care Medical Center, Saiseikai Senri Hospital, Suita, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Ehara","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Japanese Red Cross Kyoto Daiichi Hospital, Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuhiro","family":"Miyamae","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Rakuwa-kai Otowa Hospital, Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohei","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Japanese Red Cross Society Kyoto Daini Red Cross Hospital, Kyoto, Japan."},{"name":"Health Services and Systems Research, Duke-NUS Medical School, National University of Singapore, Singapore, Singapore."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takaaki","family":"Jo","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Uji-Tokushukai Medical Center, Uji, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuyuki","family":"Sumida","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Rakuwa-kai Otowa Hospital, Kyoto, Japan."},{"name":"Department of Emergency Medicine, North Medical Center, Kyoto Prefectural University of Medicine, Yosa-gun, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobunaga","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan."},{"name":"Department of Emergency Medicine, Japanese Red Cross Kyoto Daiichi 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