{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T19:14:55Z","timestamp":1783624495846,"version":"3.55.0"},"reference-count":25,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T00:00:00Z","timestamp":1747267200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Hypothermia and Temperature Management"],"published-print":{"date-parts":[[2026,9,1]]},"abstract":"<jats:p>\n                    The objective of this study was to assess the adherence to inclusion criteria for therapeutic hypothermia (TH) in neonates with hypoxic-ischemic encephalopathy (HIE) and to survey current attitudes on TH. This multicenter observational study therefore combined a retrospective analysis of the Swiss National Asphyxia and Cooling Register (2011\u20132023) and a prospective survey (2024) among neonatologists in the Canton of Zurich, Switzerland. A total of 456 neonates with HIE were registered in the Swiss National Asphyxia and Cooling Register in the Canton of Zurich, Switzerland, between 2011 and 2023. The rate of TH (52.6% [2011\u20132017] versus 52.0% [2018\u20132023]) as well as the incidence of off-protocol cooling remained stable over time (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    = 0.614). The survey response rate was 69.5% (57\/82). Difficulties with clinical grading of encephalopathy were identified. Subjectively, respondents considered themselves more generous to initiate TH. In conclusion, register data reflected good adherence to inclusion criteria for TH. The survey confirmed willingness to consider TH in milder HIE cases. However, there was no drift in clinical practice\u2014yet?\n                  <\/jats:p>","DOI":"10.1089\/ther.2025.0019","type":"journal-article","created":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T04:20:21Z","timestamp":1747282821000},"page":"107-115","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Therapeutic Hypothermia in Neonates with Hypoxic-Ischemic Encephalopathy\u2014Drift in Clinical Practice in Swiss Neonatal (Intensive Care) Units?"],"prefix":"10.1177","volume":"16","author":[{"given":"Charlotte","family":"Lengauer","sequence":"first","affiliation":[{"name":"Newborn Research, Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Adams","sequence":"additional","affiliation":[{"name":"Newborn Research, Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Brotschi","sequence":"additional","affiliation":[{"name":"Department of Intensive Care and Neonatology, University Children\u2019s Hospital Zurich, Zurich, Switzerland."},{"name":"Children\u2019s Research Center, University Children\u2019s Hospital of Zurich, University of Zurich, Zurich, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Kleber","sequence":"additional","affiliation":[{"name":"Clinic of Neonatology, Cantonal Hospital Winterthur, Winterthur, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera","family":"Bernet","sequence":"additional","affiliation":[{"name":"Children\u2019s Research Center, University Children\u2019s Hospital of Zurich, University of Zurich, Zurich, Switzerland."},{"name":"Department of Neonatology, Hospital Zollikerberg, Zurich, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maren","family":"Tomaske","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Neonatology, City Hospital Zurich, Zurich, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk","family":"Bassler","sequence":"additional","affiliation":[{"name":"Newborn Research, Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4965-2814","authenticated-orcid":false,"given":"Beate","family":"Grass","sequence":"additional","affiliation":[{"name":"Newborn Research, Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,5,15]]},"reference":[{"key":"e_1_3_6_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0900854"},{"key":"e_1_3_6_3_1","doi-asserted-by":"publisher","DOI":"10.1089\/ther.2022.0055"},{"key":"e_1_3_6_4_1","unstructured":"Brotschi B Latal B Rathke V et al. National Asphyxia and Cooling Register in Switzerland [Website]. paediatrie schweiz. 2014. Available from: https:\/\/www.paediatrieschweiz.ch\/fr\/national-asphyxia-and-cooling-register-in-switzerland [Last accessed: October30 2024]."},{"key":"e_1_3_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2015.02.009"},{"key":"e_1_3_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2018.02.007"},{"key":"e_1_3_6_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2014.3269"},{"key":"e_1_3_6_8_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1563712"},{"key":"e_1_3_6_9_1","doi-asserted-by":"publisher","DOI":"10.4414\/smw.2021.20489"},{"key":"e_1_3_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003311.pub3"},{"key":"e_1_3_6_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2018-315711"},{"key":"e_1_3_6_12_1","unstructured":"LimeSurvey Website. LimeSurvey: An Open Source Survey Tool. n.d. 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