{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T18:16:55Z","timestamp":1778955415580,"version":"3.51.4"},"reference-count":48,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.liebertpub.com\/nv\/resources-tools\/text-and-data-mining-policy\/121\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thyroid"],"published-print":{"date-parts":[[2020,4,1]]},"DOI":"10.1089\/thy.2019.0301","type":"journal-article","created":{"date-parts":[[2020,3,3]],"date-time":"2020-03-03T02:13:07Z","timestamp":1583201587000},"page":"487-500","source":"Crossref","is-referenced-by-count":8,"title":["<i>\n                      BRAF\n                      <sup>V600E<\/sup>\n                    <\/i>\n                    Transduction of an SV40-Immortalized Normal Human Thyroid Cell Line Induces Dedifferentiated Thyroid Carcinogenesis in a Mouse Xenograft Model"],"prefix":"10.1177","volume":"30","author":[{"given":"Minjun","family":"Kim","sequence":"first","affiliation":[{"name":"Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Su-jin","family":"Kim","sequence":"additional","affiliation":[{"name":"Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea."},{"name":"Department of Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea."},{"name":"Division of Surgery, Thyroid Center, Seoul National University Cancer Hospital, Seoul, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen","family":"Xu","sequence":"additional","affiliation":[{"name":"Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea."},{"name":"Department of Surgery, YanBian University Hospital, Yanji, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seong Yun","family":"Ha","sequence":"additional","affiliation":[{"name":"Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae Hwan","family":"Byeon","sequence":"additional","affiliation":[{"name":"Department of Statistics, Yonsei Graduate School of Public Health, Seoul, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eun Ji","family":"Kang","sequence":"additional","affiliation":[{"name":"Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung-Hyun","family":"Shin","sequence":"additional","affiliation":[{"name":"Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seong-Keun","family":"Yoo","sequence":"additional","affiliation":[{"name":"Precision Medicine Institute, Macrogen, Inc., Seongnam, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyeon-Gun","family":"Jee","sequence":"additional","affiliation":[{"name":"Healthcare Innovation Park, Seoul National University Bundang Hospital, Seongnam, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Gab","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kosin University Gospel Hospital, Busan, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin Wook","family":"Yi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Inha University Hospital, Incheon, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong Mo","family":"Bae","sequence":"additional","affiliation":[{"name":"Department of Pathology, Seoul National University College of Medicine, Seoul, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyeong Won","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Surgery, Seoul National University Bundang Hospital, Seongnam, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Jun","family":"Chai","sequence":"additional","affiliation":[{"name":"Department of Surgery, Seoul National University Boramae Medical Center, Seoul, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun Wook","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"June Young","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Seoul National University Bundang Hospital, Seongnam, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyu Eun","family":"Lee","sequence":"additional","affiliation":[{"name":"Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea."},{"name":"Department of Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea."},{"name":"Division of Surgery, Thyroid Center, Seoul National University Cancer Hospital, Seoul, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wonshik","family":"Han","sequence":"additional","affiliation":[{"name":"Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea."},{"name":"Department of Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)62242-X"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.09.050"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1006239"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-18-0373"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2015.0139"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2011.02.004"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.73.6785"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-4463"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1404357111"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2014-2624"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2012.00133"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-18-2953"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03033-1"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.55.5094"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2016.0547"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.56.8253"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.3190"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.21873\/cgp.20018"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1989.387"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(88)90559-4"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1101\/gad.6.10.1886"},{"key":"B25","first-page":"2805","volume":"8","author":"Jiang D","year":"1993","journal-title":"Oncogene"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3317"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.3122"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1209046"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1210\/er.2007-0007"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1201543"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2008.11.024"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a026104"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(91)90181-W"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.14.3.2077"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.6.4.371"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1177\/030098589803500601"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4160-5766-6.00022-4"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2009.23"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/j.jim.2006.01.022"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.6.000124"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-25383-y"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-07-1515"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-16-1495"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-020436"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.06.1291"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2010.03.013"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1158\/1541-7786.MCR-07-2001"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-0373"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2013.0483"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2018.07.001"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-9145-7_15"}],"container-title":["Thyroid"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.liebertpub.com\/doi\/full-xml\/10.1089\/thy.2019.0301","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.liebertpub.com\/doi\/pdf\/10.1089\/thy.2019.0301","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:06:14Z","timestamp":1777586774000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/thy.2019.0301"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,1]]},"references-count":48,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4,1]]}},"alternative-id":["10.1089\/thy.2019.0301"],"URL":"https:\/\/doi.org\/10.1089\/thy.2019.0301","relation":{},"ISSN":["1050-7256","1557-9077"],"issn-type":[{"value":"1050-7256","type":"print"},{"value":"1557-9077","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,1]]}}}