{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T16:53:42Z","timestamp":1779296022496,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Telemedicine and e-Health"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Autonomic dysfunction has been implicated as a consequence of traumatic brain injury (TBI). Heart rate variability (HRV) may be a viable measure of autonomic dysfunction that could enhance rehabilitative interventions for individuals with TBI. This pilot study sought to assess the feasibility and validity of using the Zeriscope\u2122 platform system in a real-world clinical setting to measure HRV in active-duty service members with TBI who were participating in an intensive outpatient program.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Twenty-five service members with a history of mild, moderate, or severe TBI were recruited from a military treatment facility. A baseline assessment was conducted in the cardiology clinic where point validity data were obtained by comparing a 5-min recording of a standard 12-lead electrocardiogram (ECG) output against the Zeriscope platform data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Compared with the ECG device, the Zeriscope device had a concordance coefficient (\n                      <jats:italic toggle=\"yes\">rc<\/jats:italic>\n                      ) of 0.16, falling below the standard deemed to represent acceptable accuracy in HR measurement (i.e., 0.80). Follow-up analyses excluding outliers did not significantly improve the concordance coefficient to an acceptable standard for the total participant sample. System Usability Survey responses showed that participants rated the Zeriscope system as easy to use and something that most people would learn to use quickly.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This study demonstrated promise in ambulatory HRV measurement in a representative military TBI sample. Future research should include further refinement of such ambulatory devices to meet the specifications required for use in a military active-duty TBI population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/tmj.2021.0627","type":"journal-article","created":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T17:27:16Z","timestamp":1646155636000},"page":"1496-1504","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Assessing the Clinical Utility of a Wearable Device for Physiological Monitoring of Heart Rate Variability in Military Service Members with Traumatic Brain Injury"],"prefix":"10.1177","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4565-7906","authenticated-orcid":false,"given":"Jay M.","family":"Uomoto","sequence":"first","affiliation":[{"name":"Traumatic Brain Injury Center of Excellence Research and Engineering Directorate, Defense Health Agency\u2013Joint Base Lewis-McChord, General Dynamics Information Technology, Tacoma, Washington, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy","family":"Skopp","sequence":"additional","affiliation":[{"name":"Psychological Health Center of Excellence Research and Engineering Directorate, Defense Health Agency, Tacoma, Washington, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Jenkins-Guarnieri","sequence":"additional","affiliation":[{"name":"Mental Health Service, Department of Veterans Affairs, Robley Rex VA Medical Center, Louisville, Kentucky, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5605-3740","authenticated-orcid":false,"given":"Josh","family":"Reini","sequence":"additional","affiliation":[{"name":"The Henry M Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA."},{"name":"Center for Rehabilitation Sciences Research at the Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA."},{"name":"Department of Rehabilitation, Walter Reed National Military Medical Center, Bethesda, Maryland, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Drew","family":"Thomas","sequence":"additional","affiliation":[{"name":"Madigan Army Medical Center, Tacoma, Washington, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert J.","family":"Adams","sequence":"additional","affiliation":[{"name":"Department of Neurology, Medical University of South Carolina Neurology, Charleston, South Carolina, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan","family":"Tsui","sequence":"additional","affiliation":[{"name":"The Henry M Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA."},{"name":"Center for Rehabilitation Sciences Research at the Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA."},{"name":"Department of Rehabilitation, Walter Reed National Military Medical Center, Bethesda, Maryland, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaun R.","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Madigan Army Medical Center, Tacoma, Washington, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beverly R.","family":"Scott","sequence":"additional","affiliation":[{"name":"Madigan Army Medical Center, Tacoma, Washington, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul F.","family":"Pasquina","sequence":"additional","affiliation":[{"name":"Center for Rehabilitation Sciences Research at the Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA."},{"name":"Department of Rehabilitation, Walter Reed National Military Medical Center, Bethesda, Maryland, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,10,7]]},"reference":[{"key":"e_1_3_5_2_2","unstructured":"DHA TBI Center of Excellence. DoD numbers for traumatic brain injury: Worldwide\u2014Totals. Available at https:\/\/health.mil\/About-MHS\/OASDHA\/Defense-Health-Agency\/Research-and-Development\/Traumatic-Brain-Injury-Center-of-Excellence\/DoD-TBI-Worldwide-Numbers (last accessed January22 2021)."},{"key":"e_1_3_5_3_2","unstructured":"Centers for Disease Control and Prevention. Surveillance Report of Traumatic Brain Injury-related Emergency Department Visits Hospitalizations and Deaths\u2014United States 2014. 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