{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T05:18:48Z","timestamp":1778908728827,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Telemedicine and e-Health"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Growth of international travel to malarial areas over the last decades has contributed to more travelers taking malaria prophylaxis. Travel-related symptoms may be wrongly attributed to malaria prophylaxis and hinder compliance. Here, we aimed to assess the frequency of real-time reporting of symptoms by travelers following malaria prophylaxis using a smartphone app.<\/jats:italic>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">\n                        Adult international travelers included in this single-center study (Barcelona, Spain) used the smartphone Trip Doctor\n                        <jats:sup>\u00ae<\/jats:sup>\n                        app developed by our group for real-time tracking of symptoms and adherence to prophylaxis.\n                      <\/jats:italic>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Six hundred four (<\/jats:italic>\n                      n\n                      <jats:italic toggle=\"yes\">\u2009=\u2009604) international travelers were included in the study; 74.3% (449) used the app daily, and for one-quarter of travelers, malaria prophylaxis was prescribed. Participants from the prophylaxis group traveled more to Africa (86.7% vs. 4.3%;<\/jats:italic>\n                      p\n                      <jats:italic toggle=\"yes\">&lt; 0.01) and to high travel medical risk countries (60.8% vs. 18%;<\/jats:italic>\n                      p\n                      <jats:italic toggle=\"yes\">&lt; 0.01) and reported more immunosuppression (30.8% vs. 23.1%<\/jats:italic>\n                      p\n                      <jats:italic toggle=\"yes\">&lt; 0.01). Regarding symptoms, no significant intergroup differences were observed, and no relationship was found between the total number of malarial pills taken and reported symptoms.<\/jats:italic>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">In our cohort, the number of symptoms due to malaria prophylaxis was not significantly higher than in participants for whom prophylaxis was not prescribed, and the overall proportion of symptoms is higher compared with other studies.<\/jats:italic>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/tmj.2023.0200","type":"journal-article","created":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T14:52:26Z","timestamp":1705071146000},"page":"1436-1442","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["A Smartphone App for Real-Time Assessment of Malaria Prophylaxis Adverse Events"],"prefix":"10.1177","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5693-0974","authenticated-orcid":false,"given":"Natalia","family":"Rodriguez-Valero","sequence":"first","affiliation":[{"name":"ISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Cl\u00ednic, Department of International Health, Universitat de Barcelona, Barcelona, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Jesus","family":"Ledesma-Carbayo","sequence":"additional","affiliation":[{"name":"Biomedical Image Technology, Electronic Engineering, Universidad Polit\u00e9cnica de Madrid and CIBER-BBN, Madrid, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helena","family":"Mart\u00ed-Soler","sequence":"additional","affiliation":[{"name":"ISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Cl\u00ednic, Department of International Health, Universitat de Barcelona, Barcelona, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Cuadrado Sanchez","sequence":"additional","affiliation":[{"name":"Biomedical Image Technology, Electronic Engineering, Universidad Polit\u00e9cnica de Madrid and CIBER-BBN, Madrid, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Vladimirov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Camprub\u00ed-Ferrer","sequence":"additional","affiliation":[{"name":"ISGlobal, Barcelona Centre for International 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