{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T03:20:39Z","timestamp":1787714439384,"version":"build-2784847793"},"reference-count":20,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Transgender Health"],"published-print":{"date-parts":[[2024,8,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>We aimed to investigate how adults, who started gender-affirming hormone treatment during adolescence, reflect on their reproductive decisions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We recruited transgender and gender-diverse (TGD) people who visited our gender identity clinic and commenced medical treatment in adolescence at least 9 years ago. We collected data through an online survey.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The cohort consisted of 89 participants (66 TGD people assigned female at birth (AFAB) and 23 TGD people assigned male at birth (AMAB) with a mean age of 32.4 years (range 25.5\u201351.2) at the time of study, and 15.6 years (range 11.5\u201320.6) at the start of medical treatment. All participants initiated medical treatment before 2014, when laws requiring sterilization for legal gender recognition were still in place, and only 30% of participants reported to have received information about fertility preservation, which none of them pursued. In addition, 96% of participants underwent gonadectomy and thus became permanently infertile, which was troublesome for 27%. With today's knowledge, 44% of TGD people AFAB and 35% of TGD people born AMAB would pursue fertility preservation. The percentage of participants with a (future) desire for children increased from 34% at the start of medical treatment (at adolescent age) to 56% at the time of this study (at adult age), of whom 23% had currently started a family.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>It is important to inform transgender adolescents about the effect of medical treatment on fertility and the options for fertility preservation since many may develop a desire for (biological) children when they reach adulthood.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/trgh.2022.0135","type":"journal-article","created":{"date-parts":[[2023,4,19]],"date-time":"2023-04-19T10:57:55Z","timestamp":1681901875000},"page":"298-306","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Reflecting on the Importance of Family Building and Fertility Preservation: Transgender People's Experiences with Starting Gender-Affirming Treatment as an Adolescent"],"prefix":"10.1177","volume":"9","author":[{"given":"Iris","family":"de Nie","sequence":"first","affiliation":[{"name":"Department of Endocrinology, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands."},{"name":"Center of Expertise on Gender Dysphoria, Amsterdam UMC, Amsterdam, the Netherlands."},{"name":"Department of Obstetrics and Gynecology, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands."},{"name":"Amsterdam Reproduction and Development Research Institute, Amsterdam, the Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3823-529X","authenticated-orcid":false,"given":"Joyce D.","family":"Asseler","sequence":"additional","affiliation":[{"name":"Center of Expertise on Gender Dysphoria, Amsterdam UMC, Amsterdam, the Netherlands."},{"name":"Department of Obstetrics and Gynecology, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands."},{"name":"Amsterdam Reproduction and Development Research Institute, Amsterdam, the Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marijn","family":"Arnoldussen","sequence":"additional","affiliation":[{"name":"Center of Expertise on Gender Dysphoria, Amsterdam UMC, Amsterdam, the Netherlands."},{"name":"Department of Child and Adolescent Psychiatry, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silke","family":"Baas","sequence":"additional","affiliation":[{"name":"Center of Expertise on Gender Dysphoria, Amsterdam UMC, Amsterdam, the Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annelou L.C.","family":"de Vries","sequence":"additional","affiliation":[{"name":"Center of Expertise on Gender Dysphoria, Amsterdam UMC, Amsterdam, the Netherlands."},{"name":"Department of Child and Adolescent Psychiatry, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith A.F.","family":"Huirne","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands."},{"name":"Amsterdam Reproduction and Development Research Institute, Amsterdam, the Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas D.","family":"Steensma","sequence":"additional","affiliation":[{"name":"Center of Expertise on Gender Dysphoria, Amsterdam UMC, Amsterdam, the Netherlands."},{"name":"Department of Medical Psychology, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"den Heijer","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands."},{"name":"Center of Expertise on Gender Dysphoria, Amsterdam UMC, Amsterdam, the Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norah M.","family":"van Mello","sequence":"additional","affiliation":[{"name":"Center of Expertise on Gender Dysphoria, Amsterdam UMC, Amsterdam, the Netherlands."},{"name":"Department of Obstetrics and Gynecology, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, the Netherlands."},{"name":"Amsterdam Reproduction and Development Research Institute, Amsterdam, the Netherlands."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,8,16]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1080\/26895269.2022.2100644"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrurol.2014.316"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1743-6109.2008.00870.x"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-2958"},{"issue":"4","key":"e_1_3_5_6_2","first-page":"874","article-title":"Electronic address aao","volume":"115","author":"Ethics Committee of the American Society for Reproductive Medicine","year":"2021","unstructured":"Ethics Committee of the American Society for Reproductive Medicine. 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