{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T12:09:29Z","timestamp":1791202169667,"version":"4.2.0"},"reference-count":0,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T00:00:00Z","timestamp":1207008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vector-Borne and Zoonotic Diseases"],"published-print":{"date-parts":[[2008,4]]},"abstract":"<jats:p>\n                    An epidemic of Chikungunya fever, a mosquito-borne viral disease, spectacularly swept through R\u00e9union Island (population 780,000) in 2005\u20132006. There were 3000 cases in a first wave (March\u2013June 2005) and more than 250,000 cases in a second (December 2005\u2013April 2006). Adapting newly developed epidemiological tools to vector-borne diseases, we show that despite this massive difference in magnitude, the transmission potential as measured by the number of secondary cases per index case (or reproduction number), remained similar during the two consecutive waves. The best estimate for the initial reproduction number R\n                    <jats:sub>0<\/jats:sub>\n                    was 3.7, with a possible range from 2 to 11 depending on incubation duration and lifespan of the mosquito. We conclude that an increase in virulence between the two seasons was not necessary to explain the change in magnitude of the epidemics, and that the attack rate may be well over 50% in Chikungunya fever epidemics in the absence of intervention.\n                  <\/jats:p>","DOI":"10.1089\/vbz.2006.0620","type":"journal-article","created":{"date-parts":[[2008,1,2]],"date-time":"2008-01-02T10:57:28Z","timestamp":1199271448000},"page":"207-218","source":"Crossref","is-referenced-by-count":53,"title":["Investigating Transmission in a Two-Wave Epidemic of Chikungunya Fever, R\u00e9union Island"],"prefix":"10.1177","volume":"8","author":[{"given":"P.-Y.","family":"Bo\u00eblle","sequence":"first","affiliation":[{"name":"Universit\u00e9 Pierre et Marie Curie \u2013 Paris\u00f3, UMR S 707, Paris, France."},{"name":"INSERM, UMR S 707, Paris, France."},{"name":"Assistance Publique-H\u00f4pitaux de Paris, H\u00f3pital Saint-Antoine, Paris, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Thomas","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Pierre et Marie Curie \u2013 Paris\u00f3, UMR S 707, Paris, France."},{"name":"INSERM, UMR S 707, Paris, France."},{"name":"Assistance Publique-H\u00f4pitaux de Paris, H\u00f3pital Saint-Antoine, Paris, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Vergu","sequence":"additional","affiliation":[{"name":"INRA, MIAJ, Jouy en Josas, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Renault","sequence":"additional","affiliation":[{"name":"CIRE R\u00e9union Mayotte, DRASS, R\u00e9union, Saint Denis, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.-J.","family":"Valleron","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Pierre et Marie Curie \u2013 Paris\u00f3, UMR S 707, Paris, France."},{"name":"INSERM, UMR S 707, Paris, France."},{"name":"Assistance Publique-H\u00f4pitaux de Paris, H\u00f3pital Saint-Antoine, Paris, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Flahault","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Pierre et Marie Curie \u2013 Paris\u00f3, UMR S 707, Paris, France."},{"name":"INSERM, UMR S 707, Paris, France."},{"name":"Assistance Publique-H\u00f4pitaux de Paris, H\u00f3pital Saint-Antoine, Paris, France."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2008,4,1]]},"container-title":["Vector-Borne and Zoonotic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/vbz.2006.0620","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/vbz.2006.0620","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:43:48Z","timestamp":1777589028000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/vbz.2006.0620"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,4]]}},"alternative-id":["10.1089\/vbz.2006.0620"],"URL":"https:\/\/doi.org\/10.1089\/vbz.2006.0620","relation":{},"ISSN":["1530-3667","1557-7759"],"issn-type":[{"value":"1530-3667","type":"print"},{"value":"1557-7759","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,4]]}}}