{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T20:08:50Z","timestamp":1791058130257,"version":"4.1.0"},"reference-count":11,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vector-Borne and Zoonotic Diseases"],"published-print":{"date-parts":[[2010,11]]},"abstract":"\n We evaluated the prevalence of selected vector-borne diseases in 131 dogs in an animal shelter in central Spain using point-of-care assays (SNAP 4DX and SNAP Leishmania; IDEXX Laboratories, Westbrook, ME). The SNAP 4DX detects\n Dirofilaria immitis<\/jats:italic>\n (\n Di<\/jats:italic>\n ) antigen and antibodies against\n Ehrlichia canis<\/jats:italic>\n (\n Ec<\/jats:italic>\n ),\n Borrelia burgdorferi<\/jats:italic>\n (\n Bb<\/jats:italic>\n ), and\n Anaplasma phagocytophylum<\/jats:italic>\n (\n Aph<\/jats:italic>\n ); the SNAP Leishmania kit detects antibodies against\n Leishmania infantum<\/jats:italic>\n (\n Li<\/jats:italic>\n ). Dogs were classified as healthy or sick based on physical examination, complete blood counts, and serum chemistry profiles. The prevalence of positive test results was as follows:\n Ec<\/jats:italic>\n , 5.3% (\n n<\/jats:italic>\n \u2009=\u20097);\n Aph<\/jats:italic>\n , 19.0% (\n n<\/jats:italic>\n \u2009=\u200925);\n Bb<\/jats:italic>\n , 0%;\n Di<\/jats:italic>\n , 0%; and\n Li<\/jats:italic>\n , 5.3% (\n n<\/jats:italic>\n \u2009=\u20097). Four dogs (3%) were coexposed to\n Ec<\/jats:italic>\n and\n Aph<\/jats:italic>\n , and three dogs (2.3%) were coexposed to\n Aph<\/jats:italic>\n and\n Li<\/jats:italic>\n . There was no statistically significant correlation between positive serology and clinical status (sick vs. healthy) or hematologic\/biochemical abnormalities. The prevalence of\n Aph<\/jats:italic>\n was the highest and is in agreement with a recent report in a dog shelter in northwestern Spain. These point-of-care assays may be more valuable as epidemiologic than as clinical tools.\n <\/jats:p>","DOI":"10.1089\/vbz.2009.0063","type":"journal-article","created":{"date-parts":[[2010,4,26]],"date-time":"2010-04-26T21:11:01Z","timestamp":1272316261000},"page":"885-888","source":"Crossref","is-referenced-by-count":29,"title":["Serological Study of Selected Vector-Borne Diseases in Shelter Dogs in Central Spain Using Point-of-Care Assays"],"prefix":"10.1177","volume":"10","author":[{"given":"C. Guillermo","family":"Couto","sequence":"first","affiliation":[{"name":"The Ohio State University"},{"name":"The Ohio State University"},{"name":"The Ohio State University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leif","family":"Lorentzen","sequence":"additional","affiliation":[{"name":"IDEXX Laboratories"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa J.","family":"Beall","sequence":"additional","affiliation":[{"name":"IDEXX Laboratories"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Shields","sequence":"additional","affiliation":[{"name":"IDEXX Laboratories"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolette","family":"Bertolone","sequence":"additional","affiliation":[{"name":"The Ohio State University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason I.","family":"Couto","sequence":"additional","affiliation":[{"name":"The Ohio State University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen M.","family":"Couto","sequence":"additional","affiliation":[{"name":"The Ohio State University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Nash","sequence":"additional","affiliation":[{"name":"The Ohio State University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Slack","sequence":"additional","affiliation":[{"name":"The Ohio State University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Kvitko","sequence":"additional","affiliation":[{"name":"The Ohio State University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Westendorf","sequence":"additional","affiliation":[{"name":"The Ohio State University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliana","family":"Marin","sequence":"additional","affiliation":[{"name":"The Ohio State University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Christina","family":"Iazbik","sequence":"additional","affiliation":[{"name":"The Ohio State University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco Clemente","family":"Vicario","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Veterinaria Merced","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Sanz","sequence":"additional","affiliation":[{"name":"Studio Veterinario Bisio-Sangiorgio-Tagliabue","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Ruano","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Mediterr\u00e1neo","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2010,11,1]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1089\/vbz.2007.0277"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1089\/vbz.2007.0236"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.9.3506-3508.2002"},{"key":"e_1_3_3_5_1","first-page":"145","article-title":"Serologic diagnosis of equine borreliosis: evaluation of an in-clinic enzyme-linked immunosorbent assay (SNAP\u00ae 4DX\u00ae)","volume":"6","author":"Chadrashekar R","year":"2008","unstructured":"Chadrashekar R, , Daniluk D, , Moffitt S, , Lorentzen L, , Williams J. Serologic diagnosis of equine borreliosis: evaluation of an in-clinic enzyme-linked immunosorbent assay (SNAP\u00ae 4DX\u00ae) Int J Appl Res Vet Med, 2008; 6:145\u2013150.","journal-title":"Int J Appl Res Vet Med"},{"key":"e_1_3_3_6_1","doi-asserted-by":"crossref","unstructured":"Fern\u00e1ndez-Soto P D\u00edaz-Mart\u00edn V P\u00e9rez-S\u00e1nchez R Encinas-Grandes A. Increased prevalence of Rickettsia aeschlimannii in Castilla and Le\u00f3n Spain. Eur J Clin Microbiol Infect Dis 2008[EPub ahead of print]","DOI":"10.1007\/s10096-008-0667-3"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2006.09.017"},{"key":"e_1_3_3_8_1","first-page":"1322","volume-title":"Small Animal Internal Medicine","author":"Lappin MR","year":"2009","unstructured":"Lappin MR. Polysystemic rickettsial diseases. Nelson RW, , Couto CG. Small Animal Internal Medicine, 4th. St. Louis, MO: Elsevier, 2009; 1322\u20131335.","edition":"4"},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1411.071221"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.67.2.206"},{"key":"e_1_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.2004.65.1200"},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1051\/vetres:2005054"}],"container-title":["Vector-Borne and Zoonotic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/vbz.2009.0063","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/vbz.2009.0063","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/vbz.2009.0063","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:46:50Z","timestamp":1777589210000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/vbz.2009.0063"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11]]},"references-count":11,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["10.1089\/vbz.2009.0063"],"URL":"https:\/\/doi.org\/10.1089\/vbz.2009.0063","relation":{},"ISSN":["1530-3667","1557-7759"],"issn-type":[{"value":"1530-3667","type":"print"},{"value":"1557-7759","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,11]]}}}