{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T00:42:30Z","timestamp":1792197750348,"version":"4.4.0"},"reference-count":60,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vector-Borne and Zoonotic Diseases"],"published-print":{"date-parts":[[2011,2]]},"abstract":"<jats:p>\n                    The epidemiology of vector-borne zoonotic diseases is determined by encounter rates between vectors and hosts. Alterations to the behavior of reservoir hosts caused by the infectious agent have the potential to dramatically alter disease transmission and human risk. We examined the effect of\n                    <jats:italic toggle=\"yes\">Borrelia burgdorferi<\/jats:italic>\n                    , the etiological agent of Lyme disease, on one of its most important reservoir hosts, the white-footed mouse,\n                    <jats:italic toggle=\"yes\">Peromyscus leucopus<\/jats:italic>\n                    . We mimic natural infections in mice using the vector (Black-legged ticks,\n                    <jats:italic toggle=\"yes\">Ixodes scapularis<\/jats:italic>\n                    ) and examine the immunological and behavioral responses of mouse hosts. Despite producing antibodies against\n                    <jats:italic toggle=\"yes\">B. burgdorferi<\/jats:italic>\n                    , infected mice did not have elevated white blood cells compared with uninfected mice. In addition, infected and uninfected mice did not differ in their wheel-running activity. Our results suggest that infection with the spirochete\n                    <jats:italic toggle=\"yes\">B. burgdorferi<\/jats:italic>\n                    has little impact on the field activity of white-footed mice. Lyme disease transmission appears to be uncomplicated by pathogen-altered behavior of this reservoir host.\n                  <\/jats:p>","DOI":"10.1089\/vbz.2009.0215","type":"journal-article","created":{"date-parts":[[2010,6,23]],"date-time":"2010-06-23T12:14:51Z","timestamp":1277295291000},"page":"117-124","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":69,"title":["<i>Borrelia burgdorferi<\/i>\n                    Has Minimal Impact on the Lyme Disease Reservoir Host\n                    <i>Peromyscus leucopus<\/i>"],"prefix":"10.1177","volume":"11","author":[{"given":"Lisa E.","family":"Schwanz","sequence":"first","affiliation":[{"name":"Cary Institute of Ecosystem Studies"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maarten J.","family":"Voordouw","sequence":"additional","affiliation":[{"name":"University of Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dustin","family":"Brisson","sequence":"additional","affiliation":[{"name":"University of Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard S.","family":"Ostfeld","sequence":"additional","affiliation":[{"name":"Cary Institute of Ecosystem Studies"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2011,2,1]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1086\/589892"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.25.8.1564-1566.1987"},{"key":"e_1_3_3_4_1","first-page":"263","article-title":"Kinetics of Borrelia burgdorferi dissemination and evolution of disease after intradermal inoculation of mice","volume":"139","author":"Barthold SW","year":"1991","unstructured":"Barthold SW, , Persing DH, , Armstrong AL, , Peeples RA. 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