{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T18:34:55Z","timestamp":1788287695667,"version":"build-2803163510"},"reference-count":32,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vector-Borne and Zoonotic Diseases"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Bartonella<\/jats:italic>\n                      species are important emerging pathogens in human and veterinary medicine. In the context of their daily activities, veterinary professionals have frequent animal contact and arthropod exposures. Detection of\n                      <jats:italic toggle=\"yes\">Bartonella<\/jats:italic>\n                      spp. using traditional culture methods has been limited by poor sensitivity, making it difficult to determine the prevalence of infection in this population. We have developed a detection method combining enrichment culture and molecular amplification, which increases testing sensitivity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      We performed a cross-sectional study to determine the prevalence of detectable\n                      <jats:italic toggle=\"yes\">Bartonella<\/jats:italic>\n                      spp. in the blood of veterinary personnel and nonveterinary control subjects.\n                      <jats:italic toggle=\"yes\">Bartonella<\/jats:italic>\n                      was detected by enrichment blood culture with conventional PCR followed by DNA sequencing. Results were correlated with epidemiological variables and symptoms.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      We detected DNA from at least one\n                      <jats:italic toggle=\"yes\">Bartonella<\/jats:italic>\n                      species in 32 (28%) of the 114 veterinary subjects. After DNA sequencing, the\n                      <jats:italic toggle=\"yes\">Bartonella<\/jats:italic>\n                      species could be determined for 27 of the 32 infected subjects, including\n                      <jats:italic toggle=\"yes\">B. henselae<\/jats:italic>\n                      in 15 (56%),\n                      <jats:italic toggle=\"yes\">B. vinsonii<\/jats:italic>\n                      subsp.\n                      <jats:italic toggle=\"yes\">berkhoffii<\/jats:italic>\n                      in seven (26%),\n                      <jats:italic toggle=\"yes\">B. koehlerae<\/jats:italic>\n                      in six (22%), and a\n                      <jats:italic toggle=\"yes\">B. volans<\/jats:italic>\n                      \u2013like sequence in one (4%). Seventy percent of\n                      <jats:italic toggle=\"yes\">Bartonella<\/jats:italic>\n                      -positive subjects described headache compared with 40% of uninfected veterinarians (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      =0.009). Irritability was also reported more commonly by infected subjects (68% vs. 43%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      =0.04).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>\n                      Our study supports an emerging body of evidence that cryptic\n                      <jats:italic toggle=\"yes\">Bartonella<\/jats:italic>\n                      bloodstream infection may be more frequent in humans than previously recognized and may induce symptoms. Longitudinal studies are needed to determine the natural course and clinical features of\n                      <jats:italic toggle=\"yes\">Bartonella<\/jats:italic>\n                      infection.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/vbz.2013.1512","type":"journal-article","created":{"date-parts":[[2014,7,29]],"date-time":"2014-07-29T16:36:33Z","timestamp":1406651793000},"page":"563-570","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":60,"title":["Detection of\n                    <i>Bartonella<\/i>\n                    Species in the Blood of Veterinarians and Veterinary Technicians: A Newly Recognized Occupational Hazard?"],"prefix":"10.1177","volume":"14","author":[{"given":"Paul M.","family":"Lantos","sequence":"first","affiliation":[{"name":"Duke University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo G.","family":"Maggi","sequence":"additional","affiliation":[{"name":"North Carolina State University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandy","family":"Ferguson","sequence":"additional","affiliation":[{"name":"Duke University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay","family":"Varkey","sequence":"additional","affiliation":[{"name":"Duke University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence P.","family":"Park","sequence":"additional","affiliation":[{"name":"Duke University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward B.","family":"Breitschwerdt","sequence":"additional","affiliation":[{"name":"North Carolina State University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher W.","family":"Woods","sequence":"additional","affiliation":[{"name":"Duke University School of Medicine"},{"name":"Department of Medicine, Durham Veterans Administration Medical Center, Durham, North Carolina."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,8,1]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00239-06"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-200201000-00006"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.13.3.428"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.33.1.154-160.1995"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.11.3618-3626.1999"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1306.061337"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00832-08"},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756-3305-3-29"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00833-11"},{"key":"e_1_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-123-2-199507150-00001"},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02456-07"},{"key":"e_1_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-7435(86)90037-X"},{"key":"e_1_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2003.tb07376.x"},{"key":"e_1_3_3_15_1","first-page":"710","article-title":"The prevalence of chronic widespread pain in the general population","volume":"20","author":"Croft P","year":"1993","unstructured":"Croft P, , Rigby AS, , Boswell R, , Schollum J, et al. 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