{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T17:44:41Z","timestamp":1792172681486,"version":"4.4.0"},"reference-count":30,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vector-Borne and Zoonotic Diseases"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Arboviruses cause emerging and re-emerging infections affecting humans and animals. They are spread primarily by blood-sucking insects such as mosquitoes, ticks, midges, and sandflies. Changes in climate, ecology, demographic, land-use patterns, and increasing global travel have been linked to an upsurge in arboviral disease. Outbreaks occur periodically followed by persistent low-level circulation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>This study was undertaken to determine the seroepidemiology of selected arboviruses among febrile patients in selected lake\/river basins of Kenya.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Using a hospital-based cross-sectional descriptive survey, febrile patients were recruited and their serum samples tested for exposure to immunoglobulin M (IgM) and IgG antibodies against Crimean\u2013Congo hemorrhagic fever virus (CCHFV), Rift Valley fever virus (RVFV), West Nile virus (WNV), and chikungunya virus (CHIKV). Samples positive for CHIKV and WNV were further confirmed by the plaque reduction neutralization test (PRNT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Of the 379 samples examined, 176 were IgG positive for at least one of these arboviruses (46.4%, 95% confidence interval [CI] 41.4\u201351.5%). Virus-specific prevalence for CCHF, RVF, WN, and CHIK was 25.6%, 19.5%, 12.4%, and 2.6%, respectively. These prevalences varied significantly with geographical site (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt;0.001), with Tana recording the highest overall arboviral seropositivity. PRNT results for Alphaviruses confirmed that the actual viruses circulating in Baringo were Semliki Forest virus (SFV) and CHIKV, o'nyong nyong virus (ONNV) in Naivasha, and SFV and Sindbis virus (SINDV) in Tana delta. Among the flaviviruses tested\n                      <jats:italic toggle=\"yes\">,<\/jats:italic>\n                      WNV was circulating in all the three sites.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>There is a high burden of febrile illness in humans due to CCHFV, RVFV, WNV, and CHIKV infection in the river\/lake basin regions of Kenya.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/vbz.2014.1686","type":"journal-article","created":{"date-parts":[[2015,2,20]],"date-time":"2015-02-20T11:56:21Z","timestamp":1424433381000},"page":"124-132","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":46,"title":["Seroepidemiology of Selected Arboviruses in Febrile Patients Visiting Selected Health Facilities in the Lake\/River Basin Areas of Lake Baringo, Lake Naivasha, and Tana River, Kenya"],"prefix":"10.1177","volume":"15","author":[{"given":"Caroline","family":"Tigoi","sequence":"first","affiliation":[{"name":"International Centre of Insect Physiology and Ecology","place":["Kenya"]},{"name":"Jomo Kenyatta University of Agriculture and Technology","place":["Kenya"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia","family":"Lwande","sequence":"additional","affiliation":[{"name":"International Centre of Insect Physiology and Ecology","place":["Kenya"]},{"name":"Ume\u00e5 University","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedict","family":"Orindi","sequence":"additional","affiliation":[{"name":"International Centre of Insect Physiology and Ecology","place":["Kenya"]},{"name":"Katholieke Universiteit Leuven","place":["Belgium"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zephania","family":"Irura","sequence":"additional","affiliation":[{"name":"Kenyatta National Hospital grounds","place":["Kenya"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliette","family":"Ongus","sequence":"additional","affiliation":[{"name":"International Centre of Insect Physiology and Ecology","place":["Kenya"]},{"name":"Jomo Kenyatta University of Agriculture and Technology","place":["Kenya"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosemary","family":"Sang","sequence":"additional","affiliation":[{"name":"International Centre of Insect Physiology and Ecology","place":["Kenya"]},{"name":"Kenya Medical Research Institute","place":["Kenya"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,2,1]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.2411"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1214\/ss\/1009213286"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.19341-0"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1603\/033.046.0431"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1992.47.337"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2008.07.025"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0188-4409(02)00378-8"},{"key":"e_1_3_3_9_1","unstructured":"Kenya National Bureau of Statistics. 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