{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T23:55:32Z","timestamp":1783641332919,"version":"3.55.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vector-Borne and Zoonotic Diseases"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:p>\n                    The sera from healthy individuals aged 10\u201359 years randomly selected from the general population during repeated cross-sectional surveys were stored at \u221220\u00b0C at the serum bank of the National Institute of Public Health in Prague. The sera included in the present study were collected in the 1980s and in 2001 in eight districts of the Czech Republic. The proportional representation of the study localities was similar in both periods. The sera were uniformly distributed in 5-year age groups for 10- to 19-year-olds and in 10-year age groups for 20- to 59-year-olds. Males and females were nearly equally represented in both periods. Altogether 704 sera, 434 from the period 1978\u20131989 and 270 from 2001, were screened for antibodies against tick-borne encephalitis virus (TBEV) by the virus neutralization test. The seroprevalence rates were 11.5% in the 1980s and 26.3% in 2001. From the logistic regression model, it follows that the chance of detecting anti-TBEV antibodies was more than twice higher in 2001 than in 1978\u20131989 (odds ratio [OR]=2.22). The differences between males and females were not statistically significant, nor was sex\u2013period interaction. The time trends in the seropositivity rates were similar in all age groups, with the exception of the 10- to 14-year-olds (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    =0.914). The rate of seropositives in the age group 15\u201359 years increased 1.9 times, whereas that in the age group 10\u201314 years rose 5.1 times. In areas comparable to those where the study sera were collected, the average incidence rates of tick-borne encephalitis (TBE) per 100,000 population aged 10\u201359 increased significantly from 3.35 in 1978\u20131989 to 8.96 in 2001 (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt;0.001). The age-specific antibody trends in adult age groups in both periods suggest that clinically manifest or inapparent TBE cases do not induce lifelong immunity, but they are likely to reflect the previous epidemiological situation.\n                  <\/jats:p>","DOI":"10.1089\/vbz.2014.1747","type":"journal-article","created":{"date-parts":[[2015,8,14]],"date-time":"2015-08-14T14:39:44Z","timestamp":1439563184000},"page":"489-493","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Results of the Screening of Tick-Borne Encephalitis Virus Antibodies in Human Sera from Eight Districts Collected Two Decades Apart"],"prefix":"10.1177","volume":"15","author":[{"given":"Bohumir","family":"Kriz","sequence":"first","affiliation":[{"name":"National Institute of Public Health","place":["Czech Republic"]},{"name":"Charles University","place":["Czech Republic"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zdenek","family":"Hubalek","sequence":"additional","affiliation":[{"name":"The Institute of Vertebrate Biology","place":["Czech Republic"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maly","family":"Marek","sequence":"additional","affiliation":[{"name":"National Institute of Public Health","place":["Czech Republic"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milan","family":"Daniel","sequence":"additional","affiliation":[{"name":"National Institute of Public Health","place":["Czech Republic"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Strakova","sequence":"additional","affiliation":[{"name":"The Institute of Vertebrate Biology","place":["Czech Republic"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lenka","family":"Betasova","sequence":"additional","affiliation":[{"name":"The Institute of Vertebrate Biology","place":["Czech Republic"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,8,1]]},"reference":[{"key":"e_1_3_3_2_1","first-page":"50","article-title":"Child vaccination rate data in the Czech Republic those that apply to optional vaccinations (in Czech)","volume":"4","author":"Cabrnochov\u00e1 H","year":"2010","unstructured":"Cabrnochov\u00e1 H, , Skibov\u00e1 J. Child vaccination rate data in the Czech Republic those that apply to optional vaccinations (in Czech). Vakcinologie, 2010; 4:50\u201354.","journal-title":"Vakcinologie"},{"key":"e_1_3_3_3_1","first-page":"177","article-title":"Seroepidemiologic study on tick-borne encephalitis among forestry workers and farmers from the Lublin region (eastern Poland)","volume":"5","author":"Cisak E","year":"1998","unstructured":"Cisak E, , Sroka J, , Zwoli\u0144ski J, , Umi\u0144ski J. Seroepidemiologic study on tick-borne encephalitis among forestry workers and farmers from the Lublin region (eastern Poland). 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Sixty years of research of tick-borne encephalitis\u2014a basis of the current knowledge of the epidemiological situation in Central Europe. Epidemiol Mikrobiol Imunol, 2011; 60:135\u2013155.","journal-title":"Epidemiol Mikrobiol Imunol"},{"key":"e_1_3_3_6_1","first-page":"224","article-title":"Laboratorn\u00ed infekce encefalitick\u00fdm virem","volume":"88","author":"Gallia F","year":"1949","unstructured":"Gallia F, , Rampas J, , Hollender L. Laboratorn\u00ed infekce encefalitick\u00fdm virem. \u010cas L\u00e9k Ces, 1949; 88:224\u2013226.","journal-title":"\u010cas L\u00e9k Ces"},{"key":"e_1_3_3_7_1","first-page":"1","article-title":"Epidemiological studies of Lyme borreliosis and tick-borne encephalitis","volume":"92","author":"Gustafson R","year":"1994","unstructured":"Gustafson R. Epidemiological studies of Lyme borreliosis and tick-borne encephalitis. 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