{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T11:23:51Z","timestamp":1791285831977,"version":"4.1.0"},"reference-count":29,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vector-Borne and Zoonotic Diseases"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:p>\n                    Although scrub typhus and murine typhus are well-described tropical rickettsial illnesses, especially in Southeast Asia, only limited evidence is available for rickettsia-like pathogens contributing to the burden of undifferentiated febrile illness. Using commercially available kits, this study measured immunoglobulin G (IgG) antibody seroprevalence for\n                    <jats:italic toggle=\"yes\">Coxiella burnetii<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">Ehrlichia chaffeensis<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">Bartonella henselae<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">Anaplasma phagocytophilum<\/jats:italic>\n                    , and spotted fever group rickettsiae (SFGR) in 375 patients enrolled in undifferentiated febrile illness studies at Chiangrai (northern Thailand) and Mae Sot (Thai\u2013Myanmar border).\n                    <jats:italic toggle=\"yes\">Ehrlichia<\/jats:italic>\n                    and SFGR were the most common causes of IgG seropositivity. A distinct relationship between age and seropositivity was found in Chiangrai with acquisition of IgG titers against\n                    <jats:italic toggle=\"yes\">Ehrlichia<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">Bartonella<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">Anaplasma<\/jats:italic>\n                    , and SFGR in young adulthood, suggesting cumulative exposure to these pathogens. At Mae Sot, high early IgG titers against\n                    <jats:italic toggle=\"yes\">Ehrlichia<\/jats:italic>\n                    and SFGR were common, whereas\n                    <jats:italic toggle=\"yes\">Anaplasma<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">Bartonella<\/jats:italic>\n                    IgG titers increased at 50\u201360 years. Q fever associated with low IgG positivity at both study sites, with significantly higher prevalence at 30 years of age in Chiangrai. These data suggest that other rickettsial illnesses could contribute to the burden of febrile illness in Thailand and possibly adjacent regions. Improved diagnostics and better understanding of antibody longevity and cross-reactivity will improve identification and management of these easily treatable infectious diseases.\n                  <\/jats:p>","DOI":"10.1089\/vbz.2015.1776","type":"journal-article","created":{"date-parts":[[2015,5,19]],"date-time":"2015-05-19T11:42:43Z","timestamp":1432035763000},"page":"285-290","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":19,"title":["Underrecognized Arthropod-Borne and Zoonotic Pathogens in Northern and Northwestern Thailand: Serological Evidence and Opportunities for Awareness"],"prefix":"10.1177","volume":"15","author":[{"given":"Stuart D.","family":"Blacksell","sequence":"first","affiliation":[{"name":"Mahidol University","place":["Thailand"]},{"name":"University of Oxford","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pacharee","family":"Kantipong","sequence":"additional","affiliation":[{"name":"Chiangrai Prachanukhru Hospital","place":["Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanitda","family":"Watthanaworawit","sequence":"additional","affiliation":[{"name":"Mahidol University","place":["Thailand"]},{"name":"Shoklo Malaria Research Unit (SMRU)","place":["Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Turner","sequence":"additional","affiliation":[{"name":"University of Oxford","place":["United Kingdom"]},{"name":"Shoklo Malaria Research Unit (SMRU)","place":["Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ampai","family":"Tanganuchitcharnchai","sequence":"additional","affiliation":[{"name":"Mahidol University","place":["Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sutathip","family":"Jintawon","sequence":"additional","affiliation":[{"name":"Mahidol University","place":["Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Achara","family":"Laongnuanutit","sequence":"additional","affiliation":[{"name":"Chiangrai Prachanukhru Hospital","place":["Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois H.","family":"Nosten","sequence":"additional","affiliation":[{"name":"Mahidol University","place":["Thailand"]},{"name":"University of Oxford","place":["United Kingdom"]},{"name":"Shoklo Malaria Research Unit (SMRU)","place":["Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas P.J.","family":"Day","sequence":"additional","affiliation":[{"name":"Mahidol University","place":["Thailand"]},{"name":"University of Oxford","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel H.","family":"Paris","sequence":"additional","affiliation":[{"name":"Mahidol University","place":["Thailand"]},{"name":"University of Oxford","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allen L.","family":"Richards","sequence":"additional","affiliation":[{"name":"Naval Medical Research Center"},{"name":"Uniformed Services University of the Health Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,5,1]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1604.090699"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.2007.00375.x"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0060634"},{"key":"e_1_3_3_5_1","first-page":"540","article-title":"Canine ehrlichiosis (tropical canine pancytopenia) in Thailand","volume":"6","author":"Davidson DE","year":"1975","unstructured":"Davidson DE, , Dill GS, , Tingpalapong M, , Premabutra S, et al. 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