{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:35:17Z","timestamp":1791297317082,"version":"4.1.0"},"reference-count":10,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2015,11,1]],"date-time":"2015-11-01T00:00:00Z","timestamp":1446336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vector-Borne and Zoonotic Diseases"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:p>\n                    Japanese encephalitis virus (JEV) is a flavivirus that is transmitted by\n                    <jats:italic toggle=\"yes\">Culex<\/jats:italic>\n                    (\n                    <jats:italic toggle=\"yes\">Cx<\/jats:italic>\n                    .)\n                    <jats:italic toggle=\"yes\">tritaeniorhynchus<\/jats:italic>\n                    in tropical and subtropical regions of Asia. The endemic transmission cycle involves domestic pigs and avian species that serve as amplification hosts; humans are incidental hosts that cannot develop a high-titer viremia sufficient for mosquito infection. Although vaccination can be an effective strategy for disease prevention and is used extensively in multiple Asian countries, unvaccinated immunologically na\u00efve human populations can suffer from severe neurological sequelae. The potential introduction of JEV into North America would be a major threat to human and animal health. In this study, field-collected\n                    <jats:italic toggle=\"yes\">Cx. quinquefasciatus<\/jats:italic>\n                    from Valdosta, Georgia, were tested for their susceptibility to JEV and their potential to develop a disseminated infection via\n                    <jats:italic toggle=\"yes\">per os<\/jats:italic>\n                    infection. These results demonstrate that North American\n                    <jats:italic toggle=\"yes\">Cx. quinquefasciatus<\/jats:italic>\n                    are susceptible to JEV infection and subsequent dissemination at 14 days post infection (d.p.i.). Detection of viral RNA in saliva from infected mosquitoes also indicates competent vectors for JEV can be found in North America.\n                  <\/jats:p>","DOI":"10.1089\/vbz.2015.1821","type":"journal-article","created":{"date-parts":[[2015,11,13]],"date-time":"2015-11-13T10:19:19Z","timestamp":1447409959000},"page":"709-711","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":42,"title":["Susceptibility of a North American\n                    <i>Culex quinquefasciatus<\/i>\n                    to Japanese Encephalitis Virus"],"prefix":"10.1177","volume":"15","author":[{"given":"Yan-Jang S.","family":"Huang","sequence":"first","affiliation":[{"name":"Kansas State University"},{"name":"Kansas State University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie N.","family":"Harbin","sequence":"additional","affiliation":[{"name":"Kansas State University"},{"name":"Kansas State University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan M.","family":"Hettenbach","sequence":"additional","affiliation":[{"name":"Kansas State University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elin","family":"Maki","sequence":"additional","affiliation":[{"name":"Agriculture Research Service","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee W.","family":"Cohnstaedt","sequence":"additional","affiliation":[{"name":"Agriculture Research Service","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan D.T.","family":"Barrett","sequence":"additional","affiliation":[{"name":"University of Texas Medical Branch"},{"name":"University of Texas Medical Branch"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Higgs","sequence":"additional","affiliation":[{"name":"Kansas State University"},{"name":"Kansas State University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana L.","family":"Vanlandingham","sequence":"additional","affiliation":[{"name":"Kansas State University"},{"name":"Kansas State University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,11,1]]},"reference":[{"key":"e_1_3_3_2_1","first-page":"123","article-title":"Japanese encephalitis in a U.S. traveler returning from Thailand, 2004","volume":"54","author":"Centers for Disease Control and Prevention","year":"2005","unstructured":"Centers for Disease Control and Prevention. Japanese encephalitis in a U.S. traveler returning from Thailand, 2004. MMWR Morb Mortal Wkly Rep, 2005; 54:123\u2013125.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)05384-2"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2002.67.656"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.9916"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1972.21.482"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2012.12-0141"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.83.3.185"},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02686-13"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ento.54.110807.090510"},{"key":"e_1_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2004.71.120"}],"container-title":["Vector-Borne and Zoonotic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/vbz.2015.1821","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/vbz.2015.1821","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/vbz.2015.1821","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:54:08Z","timestamp":1777589648000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/vbz.2015.1821"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2015,11]]}},"alternative-id":["10.1089\/vbz.2015.1821"],"URL":"https:\/\/doi.org\/10.1089\/vbz.2015.1821","relation":{},"ISSN":["1530-3667","1557-7759"],"issn-type":[{"value":"1530-3667","type":"print"},{"value":"1557-7759","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,11]]}}}