{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T03:29:42Z","timestamp":1789788582475,"version":"4.0.1"},"reference-count":33,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vector-Borne and Zoonotic Diseases"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>\n                      Babesiosis is an emerging tick-borne disease (TBD) caused by\n                      <jats:italic toggle=\"yes\">Babesia microti<\/jats:italic>\n                      , an intracellular parasite of red blood cells. Currently, it is the highest ranked pathogen transmitted by blood transfusion. Most healthy individuals infected with\n                      <jats:italic toggle=\"yes\">B. microti<\/jats:italic>\n                      are asymptomatic, but may be at risk for chronic infection. Similar to Lyme disease transmitted by\n                      <jats:italic toggle=\"yes\">Borrelia burgdorferi<\/jats:italic>\n                      ,\n                      <jats:italic toggle=\"yes\">B. microti<\/jats:italic>\n                      is spread by\n                      <jats:italic toggle=\"yes\">Ixodes scapularis<\/jats:italic>\n                      ticks. The rate of coinfection with these TBDs in humans is unclear as most studies have focused their prevalence in ticks or rodent reservoirs.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      In this study, we aimed to determine the seroprevalence of\n                      <jats:italic toggle=\"yes\">B. microti<\/jats:italic>\n                      infection in individuals who tested positive for Lyme disease. Serum samples obtained from 130 subjects in New York were tested by immunofluorescence assay (IFA) for the presence of IgM and IgG antibodies against\n                      <jats:italic toggle=\"yes\">B. microti<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Overall, 26.9% of the serum samples tested were positive for IgM and IgG antibodies against\n                      <jats:italic toggle=\"yes\">B. microti<\/jats:italic>\n                      , suggesting exposure to TBD. Individuals who tested positive for Lyme disease as determined by two-tiered serological testing and the presence of both IgM and IgG antibodies directed against\n                      <jats:italic toggle=\"yes\">B. burgdorferi<\/jats:italic>\n                      , were significantly increased for antibodies directed against\n                      <jats:italic toggle=\"yes\">B. microti<\/jats:italic>\n                      (28.6%;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.05), suggesting the possibility of coinfection with both TBDs. In contrast, the Lyme disease-negative control group had only 6.7% of samples seropositive for\n                      <jats:italic toggle=\"yes\">B. microti<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>These findings suggest the need for more extensive studies investigating infection rates with multiple TBDs in areas where they are endemic and further support for the need to implement an FDA-approved screening test for blood products to help prevent transfusion-transmitted babesiosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/vbz.2016.2020","type":"journal-article","created":{"date-parts":[[2016,10,24]],"date-time":"2016-10-24T15:07:37Z","timestamp":1477321657000},"page":"737-743","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":33,"title":["Seroprevalence of\n                    <i>Babesia microti<\/i>\n                    in Individuals with Lyme Disease"],"prefix":"10.1177","volume":"16","author":[{"given":"Sabino R.","family":"Curcio","sequence":"first","affiliation":[{"name":"Long Island University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurel P.","family":"Tria","sequence":"additional","affiliation":[{"name":"Northwell Health Laboratories"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azad L.","family":"Gucwa","sequence":"additional","affiliation":[{"name":"Long Island University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,12,1]]},"reference":[{"key":"e_1_3_3_2_1","unstructured":"Babesiosis Surveillance\u201418 States 2011. 2012. 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