{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T07:03:06Z","timestamp":1792652586967,"version":"4.5.0"},"reference-count":22,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2020,10,28]],"date-time":"2020-10-28T00:00:00Z","timestamp":1603843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vector-Borne and Zoonotic Diseases"],"published-print":{"date-parts":[[2020,11]]},"abstract":"\n Background:<\/jats:title>\n \n Human babesiosis is an emerging zoonotic disease transmitted by ticks in China. A few systematic reports on\n Babesia<\/jats:italic>\n spp. was involved with ticks, especially in the human babesiosis endemic areas in Northeastern China.\n <\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n Ticks were collected from 30 individual waypoints along 2.0\u2009km transects in two recreational forests.\n Babesia<\/jats:italic>\n spp. infection in ticks was screened by amplifying the partial 18s rRNA gene with subsequent sequencing. Multivariate logistic regression analysis was used to determine the association between tick infection and related environmental risk factors. Cluster analyses were performed using SaTScan v6.0 software to identify any geographical cluster of infected ticks.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n A total of 2380\n Ixodes persulcatus<\/jats:italic>\n and 461\n Haemaphysalis concinna<\/jats:italic>\n ticks were collected. Of the 0.97% of\n I. persulcatus<\/jats:italic>\n ticks that tested positive, five\n Babesia<\/jats:italic>\n species were identified, including\n B. bigemina<\/jats:italic>\n (\n n<\/jats:italic>\n \u2009=\u20096)\n , B. divergens<\/jats:italic>\n (\n n<\/jats:italic>\n \u2009=\u20092)\n , B. microti<\/jats:italic>\n (\n n<\/jats:italic>\n \u2009=\u20093),\n B. venatorum<\/jats:italic>\n (\n n<\/jats:italic>\n \u2009=\u200911), and one novel strain HLJ-8. Thirteen (2.92%)\n H. concinna<\/jats:italic>\n ticks tested positive for\n B. bigemina<\/jats:italic>\n (\n n<\/jats:italic>\n \u2009=\u20091),\n B. divergens<\/jats:italic>\n (\n n<\/jats:italic>\n \u2009=\u20091), three genetic variants of\n Babesia<\/jats:italic>\n represented by HLJ-874, which was closely related to\n Babesia<\/jats:italic>\n sp.MA#361-1, and eight other\n Babesia<\/jats:italic>\n variants represented by HLJ242, which were similar to\n B. crassa<\/jats:italic>\n . Each study site had 5\u20136 different\n Babesia<\/jats:italic>\n spp. One waypoint was more likely to yield\n B. venatorum<\/jats:italic>\n (relative risk\u2009=\u200915.36,\n p<\/jats:italic>\n \u2009=\u20090.045) than all other waypoints.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n \n There exists a high genetic diversity of\n Babesia<\/jats:italic>\n spp. across a relatively small sampled region. Further study is needed to understand the risks these variants pose to human health.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1089\/vbz.2020.2635","type":"journal-article","created":{"date-parts":[[2020,8,4]],"date-time":"2020-08-04T16:18:34Z","timestamp":1596557914000},"page":"817-824","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Genetic Diversity and Coexistence of\n Babesia<\/i>\n in Ticks (Acari: Ixodidae) from Northeastern China"],"prefix":"10.1177","volume":"20","author":[{"given":"Luo-Yuan","family":"Xia","sequence":"first","affiliation":[{"name":"Graduate School of Anhui Medical University, Hefei, China."},{"name":"State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bao-Gui","family":"Jiang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting-Ting","family":"Yuan","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"von Fricken","sequence":"additional","affiliation":[{"name":"Department of Global and Community Health, George Mason University, Fairfax, Virginia, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Jia","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui-Ruo","family":"Jiang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin-Lou","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Sun","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang-Dong","family":"Ruan","sequence":"additional","affiliation":[{"name":"Academy of Forest Inventory and Planning, National Forestry and Grassland Administration, Beijing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wu-Chun","family":"Cao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia-Fu","family":"Jiang","sequence":"additional","affiliation":[{"name":"Graduate School of Anhui Medical University, Hefei, China."},{"name":"State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,10,28]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1089\/vbz.2010.0043"},{"key":"e_1_3_3_3_1","first-page":"505","article-title":"Babesiosis surveillance\u201418 States, 2011","volume":"61","author":"Barbara L","year":"2012","unstructured":"Barbara L, , Herwaldt M, , Susan Montgomery D, , Dana Woodhall M, et al. Babesiosis surveillance\u201418 States, 2011. MMWR Morb Mortal Wkly Rep, 2012; 61:505\u2013509.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1308.061560"},{"key":"e_1_3_3_5_1","first-page":"65","article-title":"Presence of potentially pathogenic Babesia sp. for human in Ixodes ricinus in Switzerland","volume":"13","author":"Casati S","year":"2006","unstructured":"Casati S, , Sager H, , Gern L, , Piffaretti J. Presence of potentially pathogenic Babesia sp. for human in Ixodes ricinus in Switzerland. Ann Agric Environ Med, 2006; 13:65\u201370.","journal-title":"Ann Agric Environ Med"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid0908.020748"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00823-06"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(14)71046-1"},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2009.03.016"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01334-06"},{"key":"e_1_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2007.03.032"},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-001-0562-7"},{"key":"e_1_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-011-2382-8"},{"key":"e_1_3_3_14_1","first-page":"26","article-title":"Detection of Babesia spp. DNA in small mammals and ixodic ticks on the territory of north Ural, west Siberia and far east of Russia","volume":"3","author":"Rar V","year":"2010","unstructured":"Rar V, , Epikhina T, , Livanova N, , Panov V, et al. Detection of Babesia spp. DNA in small mammals and ixodic ticks on the territory of north Ural, west Siberia and far east of Russia. Mol Gen Mikrobiol Virusol, 2010; 3:26\u201330.","journal-title":"Mol Gen Mikrobiol Virusol"},{"key":"e_1_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.35.2.450-454.1997"},{"key":"e_1_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2008.05.026"},{"key":"e_1_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msr121"},{"key":"e_1_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1202018"},{"key":"e_1_3_3_19_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.01913"},{"key":"e_1_3_3_20_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.39.6.2178-2183.2001"},{"key":"e_1_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.65.1015"},{"key":"e_1_3_3_22_1","first-page":"118","article-title":"Pathogen identification and clinical diagnosis for one case infected with Babesia","volume":"30","author":"Yao L","year":"2012","unstructured":"Yao L, , Ruan W, , Zeng C, , Li Z, et al. Pathogen identification and clinical diagnosis for one case infected with Babesia. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi, 2012; 30:118\u2013121 (in Chinese).","journal-title":"Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi"},{"key":"e_1_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-007-0688-3"}],"container-title":["Vector-Borne and Zoonotic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/vbz.2020.2635","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/vbz.2020.2635","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/vbz.2020.2635","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:00:04Z","timestamp":1777590004000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/vbz.2020.2635"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,28]]},"references-count":22,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1089\/vbz.2020.2635"],"URL":"https:\/\/doi.org\/10.1089\/vbz.2020.2635","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/469833","asserted-by":"object"}]},"ISSN":["1530-3667","1557-7759"],"issn-type":[{"value":"1530-3667","type":"print"},{"value":"1557-7759","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,28]]}}}