{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T06:55:31Z","timestamp":1777877731691,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2021,1,28]],"date-time":"2021-01-28T00:00:00Z","timestamp":1611792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vector-Borne and Zoonotic Diseases"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:p>\n                    Questionnaire data have linked contact with ruminants to the risk of esophageal squamous cell carcinoma (ESCC) in high-risk Asian populations. To better understand this observed association, we investigated exposure to two major zoonotic ruminant pathogens relative to ESCC risk. Using enzyme-linked immunosorbent assay, immunofluorescence assay, and\n                    <jats:italic toggle=\"yes\">Brucella<\/jats:italic>\n                    microagglutination test assays, we measured immunoglobulin G anti-\n                    <jats:italic toggle=\"yes\">Coxiella burnetii<\/jats:italic>\n                    and anti-\n                    <jats:italic toggle=\"yes\">Brucella<\/jats:italic>\n                    spp. antibodies in patients with ESCC (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u2009177) and population-based controls (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u2009177) matched by age, gender, and residence area from the Golestan case\u2013control study in Iran. We found a similarly high seroprevalence of\n                    <jats:italic toggle=\"yes\">C. burnetii<\/jats:italic>\n                    in ESCC cases and controls (75% and 80%, respectively), and a similarly low seroprevalence of\n                    <jats:italic toggle=\"yes\">Brucella<\/jats:italic>\n                    spp. (0% and 0.6%, respectively). While documenting a high exposure to one of two zoonotic ruminant infections, this exposure failed to explain the observed association of ruminant contact and ESCC risk in this high-risk population.\n                  <\/jats:p>","DOI":"10.1089\/vbz.2020.2668","type":"journal-article","created":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T23:29:54Z","timestamp":1604014194000},"page":"125-127","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Association Between Serological Responses to Two Zoonotic Ruminant Pathogens and Esophageal Squamous Cell Carcinoma"],"prefix":"10.1177","volume":"21","author":[{"given":"Halie K.","family":"Miller","sequence":"first","affiliation":[{"name":"Rickettsial Zoonoses Branch and Centers for Disease Control and Prevention, Atlanta, Georgia, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robyn A.","family":"Stoddard","sequence":"additional","affiliation":[{"name":"Bacterial Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanford M.","family":"Dawsey","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dariush","family":"Nasrollahzadeh","sequence":"additional","affiliation":[{"name":"Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian C.","family":"Abnet","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arash","family":"Etemadi","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA."},{"name":"Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farin","family":"Kamangar","sequence":"additional","affiliation":[{"name":"Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran."},{"name":"Department of Biology, School of Computer, Mathematical, and Natural Sciences, Morgan State University, Baltimore, Maryland, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gwen","family":"Murphy","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masoud","family":"Sotoudeh","sequence":"additional","affiliation":[{"name":"Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilbert J.","family":"Kersh","sequence":"additional","affiliation":[{"name":"Rickettsial Zoonoses Branch and Centers for Disease Control and Prevention, Atlanta, Georgia, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza","family":"Malekzadeh","sequence":"additional","affiliation":[{"name":"Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Constanza","family":"Camargo","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,1,28]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.13.2.398-400.1981"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2008.11.007"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/oemed-2013-101802"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-04-639617"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-12-756569"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.29109"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/2008-7802.175990"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S166078"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.7150\/jca.2.136"}],"container-title":["Vector-Borne and Zoonotic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/vbz.2020.2668","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/vbz.2020.2668","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/vbz.2020.2668","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:00:17Z","timestamp":1777590017000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/vbz.2020.2668"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,28]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1089\/vbz.2020.2668"],"URL":"https:\/\/doi.org\/10.1089\/vbz.2020.2668","relation":{},"ISSN":["1530-3667","1557-7759"],"issn-type":[{"value":"1530-3667","type":"print"},{"value":"1557-7759","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,28]]}}}