{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:52:27Z","timestamp":1787500347286,"version":"build-2736575974"},"reference-count":16,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T00:00:00Z","timestamp":1622073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vector-Borne and Zoonotic Diseases"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:p>\n                    Dengue virus (DENV) is transmitted to humans by the bite of the vector\n                    <jats:italic toggle=\"yes\">Aedes aegypti<\/jats:italic>\n                    . Several researchers have suggested that the mechanism of vertical transmission of DENV in the vector is a key aspect for the prevalence of the virus in the environment and the potentiation of epidemic outbreaks of the disease. In this context and as part of an integrated study of DENV serotypes in mosquitoes of urban areas in Sinaloa, Mexico, the presence of DENV-4 in larval stages of\n                    <jats:italic toggle=\"yes\">Ae. aegypti<\/jats:italic>\n                    was evaluated to demonstrate the vertical transmission of this serotype. In total, 672 larvae of\n                    <jats:italic toggle=\"yes\">Ae. aegypti<\/jats:italic>\n                    were collected in 16 sectors and were grouped into 36 pools, of which 41.66% (15\/36 pools) tested positive for DENV-4, with a minimum infection rate\u2009=\u200922.32. The analysis of the obtained sequences showed a 98% similarity to the DENV-4 with sequences previously reported in GenBank. These results show that\n                    <jats:italic toggle=\"yes\">Ae. aegypti<\/jats:italic>\n                    acts as a natural reservoir for DENV-4 in this region.\n                  <\/jats:p>","DOI":"10.1089\/vbz.2020.2748","type":"journal-article","created":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T18:52:07Z","timestamp":1620154327000},"page":"478-481","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Natural Vertical Transmission of Dengue Virus Serotype 4 in\n                    <i>Aedes aegypti<\/i>\n                    Larvae from Urban Areas in Sinaloa, Mexico"],"prefix":"10.1177","volume":"21","author":[{"given":"Jos\u00e9 I.","family":"Torres-Avenda\u00f1o","sequence":"first","affiliation":[{"name":"Posgrado en Ciencias Biol\u00f3gicas, Facultad de Biolog\u00eda, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annete I.","family":"Apodaca-Medina","sequence":"additional","affiliation":[{"name":"Posgrado en Ciencias Biom\u00e9dicas, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hip\u00f3lito","family":"Castillo-Ureta","sequence":"additional","affiliation":[{"name":"Posgrado en Ciencias Biol\u00f3gicas, Facultad de Biolog\u00eda, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 G.","family":"Rend\u00f3n-Maldonado","sequence":"additional","affiliation":[{"name":"Posgrado en Ciencias Biom\u00e9dicas, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edith H.","family":"Torres-Montoya","sequence":"additional","affiliation":[{"name":"Posgrado en Ciencias Biol\u00f3gicas, Facultad de Biolog\u00eda, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anah\u00ed","family":"Cota-Medina","sequence":"additional","affiliation":[{"name":"Posgrado en Ciencias Biom\u00e9dicas, Facultad de Ciencias Qu\u00edmico Biol\u00f3gicas, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan J.","family":"R\u00edos-Tostado","sequence":"additional","affiliation":[{"name":"Posgrado en Ciencias Biol\u00f3gicas, Facultad de Biolog\u00eda, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 M.","family":"Zazueta-Moreno","sequence":"additional","affiliation":[{"name":"Posgrado en Ciencias Biol\u00f3gicas, Facultad de Biolog\u00eda, Universidad Aut\u00f3noma de Sinaloa, Culiac\u00e1n, M\u00e9xico."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,5,27]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1089\/vbz.2017.2202"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0211497"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/tmi.13306"},{"key":"e_1_3_3_5_1","first-page":"52","volume-title":"Panorama Epidemiologico de Dengue 2017","author":"Direcci\u00f3n General de Epidemiolog\u00eda (DGE)","year":"2017","unstructured":"Direcci\u00f3n General de Epidemiolog\u00eda (DGE). Panorama Epidemiologico de Dengue 2017. Secretar\u00eda de Salud, M\u00e9xico: Hasta la Semana Epidemiol\u00f3gica, 2017:52."},{"key":"e_1_3_3_6_1","first-page":"52","volume-title":"Panorama Epidemiologico de Dengue 2019","author":"Direcci\u00f3n General de Epidemiolog\u00eda (DGE)","year":"2019","unstructured":"Direcci\u00f3n General de Epidemiolog\u00eda (DGE). Panorama Epidemiologico de Dengue 2019. 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Horizontal and vertical transmission of dengue virus type 2 in highly and lowly susceptible strains of Aedes aegypti mosquitoes. 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