{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T06:56:15Z","timestamp":1777877775872,"version":"3.51.4"},"reference-count":41,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vector-Borne and Zoonotic Diseases"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Objectives:<\/jats:title>\n                    <jats:p>\n                      Species of\n                      <jats:italic toggle=\"yes\">Leishmania<\/jats:italic>\n                      genus are intracellular parasites responsible for severe zoonotic diseases worldwide, such as leishmaniasis. In Brazil, the most important species is\n                      <jats:italic toggle=\"yes\">Leishmania infantum<\/jats:italic>\n                      . In the northern region, the state of Par\u00e1 is notable, with a high number of cases reported in recent years. The second largest number of cases of human visceral leishmaniasis in the region in recent years has been reported in the city of Marab\u00e1 (Par\u00e1 state). We investigated the prevalence of\n                      <jats:italic toggle=\"yes\">L. infantum<\/jats:italic>\n                      in domestic dogs from Marab\u00e1 in Amazon region in Brazil.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      A total of 400 blood samples were tested using the dual-path platform chromatographic immunoassay (DPP\n                      <jats:sup>\u00ae<\/jats:sup>\n                      CVL\u2014Bio-Manguinhos), and molecular diagnosis based in cathepsin L-\n                      <jats:italic toggle=\"yes\">like<\/jats:italic>\n                      gene, which has better specificity and sensitivity than other similar tests.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The prevalence of\n                      <jats:italic toggle=\"yes\">L. infantum<\/jats:italic>\n                      was 75.5% (302\/400) in the serological test, and 59.25% (237\/400) in molecular diagnosis, and 45.5% (182\/400) in both tests.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation and Conclusion:<\/jats:title>\n                    <jats:p>\n                      The results confirmed that the parasite\n                      <jats:italic toggle=\"yes\">L. infantum<\/jats:italic>\n                      was prevalent in the dog population of the studied region and adoption of appropriate public policies are urgently needed.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/vbz.2021.0067","type":"journal-article","created":{"date-parts":[[2021,12,13]],"date-time":"2021-12-13T15:56:32Z","timestamp":1639410992000},"page":"108-113","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Prevalence of\n                    <i>Leishmania infantum<\/i>\n                    in Dogs from Deforested Areas of the Amazon Biome"],"prefix":"10.1177","volume":"22","author":[{"given":"Caio","family":"Campolongo","sequence":"first","affiliation":[{"name":"P\u00f3s-graduate Program in Animal Medicine, Welfare, and One Health, Santo Amaro University, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan Emiliano da","family":"Silva","sequence":"additional","affiliation":[{"name":"Laboratory of Parasitic Diseases, Department of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine and Animal Science, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8212-9769","authenticated-orcid":false,"given":"Roberta Carvalho de Freitas e","family":"Azevedo","sequence":"additional","affiliation":[{"name":"P\u00f3s-graduate Program in Animal Medicine, Welfare, and One Health, Santo Amaro University, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabella Pereira","family":"Pesenato","sequence":"additional","affiliation":[{"name":"Laboratory of Parasitic Diseases, Department of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine and Animal Science, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Carolina Fernandes","family":"Carioca","sequence":"additional","affiliation":[{"name":"P\u00f3s-graduate Program in Animal Medicine, Welfare, and One Health, Santo Amaro University, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruna Farias","family":"Alves","sequence":"additional","affiliation":[{"name":"Laboratory of Parasitic Diseases, Department of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine and Animal Science, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanna Stefani Nosberto","family":"Castelli","sequence":"additional","affiliation":[{"name":"P\u00f3s-graduate Program in Animal Medicine, Welfare, and One Health, Santo Amaro University, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria Castilho","family":"Onofrio","sequence":"additional","affiliation":[{"name":"P\u00f3s-graduate Program in Animal Medicine, Welfare, and One Health, Santo Amaro University, S\u00e3o Paulo, Brazil."},{"name":"Laboratory of Zoological Collection, Butantan Institute, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arlei","family":"Marcili","sequence":"additional","affiliation":[{"name":"P\u00f3s-graduate Program in Animal Medicine, Welfare, and One Health, Santo Amaro University, S\u00e3o Paulo, Brazil."},{"name":"Laboratory of Parasitic Diseases, Department of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine and Animal Science, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,2,15]]},"reference":[{"key":"e_1_3_5_2_1","first-page":"93","article-title":"Deforestation in Amazon Settlements: History, Trends and Opportunities [in Portuguese] 1. ed","author":"Alencar A","year":"2016","unstructured":"Alencar A, , Pereira C, , Castro I, , Cardoso A, et al. 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