{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T06:57:13Z","timestamp":1777877833394,"version":"3.51.4"},"reference-count":43,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vector-Borne and Zoonotic Diseases"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Rickettsia<\/jats:italic>\n                      spp. are vector-borne zoonotic pathogens that cause febrile illness in humans. Rickettsioses is not included in the Colombian national surveillance system and is subsequently expected to be underreported. This cross-sectional study aimed to determine the seroprevalence of\n                      <jats:italic toggle=\"yes\">Rickettsia<\/jats:italic>\n                      spp. and the closely related\n                      <jats:italic toggle=\"yes\">Orientia tsutsugamushi<\/jats:italic>\n                      in two indigenous populations residing in the Sierra Nevada de Santa Marta, Colombia.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      Serum samples (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 539) were collected from the Wiwa and Koguis people between 2021 and 2022. Serum samples were screened for spotted fever group (SFG) and typhus group (TG)\n                      <jats:italic toggle=\"yes\">Rickettsia<\/jats:italic>\n                      spp. using the Fuller laboratories\n                      <jats:italic toggle=\"yes\">Rickettsia<\/jats:italic>\n                      IgG IFA kit and for\n                      <jats:italic toggle=\"yes\">O. tsutsugamushi<\/jats:italic>\n                      with the Scrub Typhus Detect\u2122 IgG ELISA.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      We observed an overall seroprevalence of 26.2% (95% confidence interval [CI] 22.5\u201330.1] for\n                      <jats:italic toggle=\"yes\">Rickettsia<\/jats:italic>\n                      spp. of the SFG, 5.4% (95% CI 3.6\u20137.6) for\n                      <jats:italic toggle=\"yes\">Rickettsia<\/jats:italic>\n                      spp. of the TG and 4.3% (95% CI 2.7\u20136.3) for\n                      <jats:italic toggle=\"yes\">O. tsutsugamushi<\/jats:italic>\n                      . Common risk factors for zoonotic disease infections were assessed for 147 of the Wiwa participants. Increased odds of seropositivity for SFG\n                      <jats:italic toggle=\"yes\">Rickettsia<\/jats:italic>\n                      spp. were observed for Wiwa participants who cared for livestock, including assisting with the birth of cattle (odds ratio [OR] = 8.85; 95% CI 1.54\u201350.90;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.015) and goats (OR = 7.60; 95% CI 1.70\u201333.90;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.008).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>\n                      These results highlight a notable exposure to\n                      <jats:italic toggle=\"yes\">Rickettsia<\/jats:italic>\n                      spp., especially the SFG, in rural Colombia. Together with recent reports of high mortality for Rocky Mountain Spotted Fever in nearby regions of South America, more detailed investigations focusing on improving knowledge and awareness as well as \u201cOne Health\u201d and \u201ccauses-of-fever\u201d studies are needed. The characterization of\n                      <jats:italic toggle=\"yes\">Rickettsia<\/jats:italic>\n                      spp. infections in humans, livestock, and tick vectors with their potential transmission routes could make a high impact on these easily treatable diseases.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/vbz.2023.0077","type":"journal-article","created":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T10:02:26Z","timestamp":1715680946000},"page":"641-648","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Seroprevalence of\n                    <i>Rickettsia<\/i>\n                    Spp. and\n                    <i>Orientia<\/i>\n                    <i>tsutsugamushi<\/i>\n                    in Indigenous Populations from the Sierra Nevada de Santa Marta, Colombia"],"prefix":"10.1177","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4085-8090","authenticated-orcid":false,"given":"Regina","family":"Oakley","sequence":"first","affiliation":[{"name":"Swiss Tropical and Public Health Institute, Allschwil, Switzerland."},{"name":"University of Basel, Basel, Switzerland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone","family":"Kann","sequence":"additional","affiliation":[{"name":"medmissio, W\u00fcrzburg, Germany."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo","family":"Concha","sequence":"additional","affiliation":[{"name":"Organizaci\u00f3n Wiwa Yugumaiun Bunkuanarua Tairona, Valledupar, Colombia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mich\u00e8le","family":"Plag","sequence":"additional","affiliation":[{"name":"Swiss Tropical and Public Health Institute, Allschwil, Switzerland."},{"name":"University of Basel, Basel, Switzerland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sven","family":"Poppert","sequence":"additional","affiliation":[{"name":"Swiss Tropical and Public Health Institute, Allschwil, Switzerland."},{"name":"University of Basel, Basel, Switzerland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Graves","sequence":"additional","affiliation":[{"name":"Australian Rickettsial Reference Laboratory, Geelong, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel H.","family":"Paris","sequence":"additional","affiliation":[{"name":"Swiss Tropical and Public Health Institute, Allschwil, Switzerland."},{"name":"University of Basel, Basel, Switzerland."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anou","family":"Dreyfus","sequence":"additional","affiliation":[{"name":"Vetsuisse Faculty, University of Z\u00fcrich, Z\u00fcrich, Switzerland."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,10,7]]},"reference":[{"key":"e_1_3_6_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01728-17"},{"key":"e_1_3_6_3_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1709.100960"},{"key":"e_1_3_6_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00553-15"},{"key":"e_1_3_6_5_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2016.1133584"},{"key":"e_1_3_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa091"},{"key":"e_1_3_6_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0009876"},{"key":"e_1_3_6_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0008858"},{"key":"e_1_3_6_9_1","doi-asserted-by":"publisher","DOI":"10.1590\/0102-311x00193617"},{"key":"e_1_3_6_10_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.16-0442"},{"key":"e_1_3_6_11_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2902.221458"},{"key":"e_1_3_6_12_1","unstructured":"Fuller Laboratories. Rickettsia screen IFA IgG antibody kit manual. 2008."},{"key":"e_1_3_6_13_1","unstructured":"Google Maps. Map of the Sierra Nevada de Santa Marta Colombia. 2023."},{"key":"e_1_3_6_14_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10071-23841"},{"key":"e_1_3_6_15_1","doi-asserted-by":"publisher","DOI":"10.1089\/vbz.2012.1173"},{"key":"e_1_3_6_16_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2008.78.321"},{"key":"e_1_3_6_17_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2007.77.378"},{"key":"e_1_3_6_18_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01526-10"},{"key":"e_1_3_6_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9092786"},{"key":"e_1_3_6_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10071427"},{"key":"e_1_3_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mimet.2008.12.012"},{"key":"e_1_3_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ttbdis.2017.02.006"},{"key":"e_1_3_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ttbdis.2017.07.007"},{"key":"e_1_3_6_24_1","unstructured":"Ministry of Health Brazil. Minist\u00e9rio da Sa\u00fade apresenta n\u00fameros da febre maculosa no Brasil; 2022. Available from: https:\/\/www.gov.br\/saude\/pt-br\/assuntos\/noticias\/2022\/junho\/ministerio-da-saude-apresenta-numeros-da-febre-maculosa-no-brasil [Last accessed: March7 2023]."},{"key":"e_1_3_6_25_1","unstructured":"Ministry of Health Brazil. Febre maculosa: Saiba como evitar e tratar a doen\u00e7a transmitida por carrapato; 2023a. Available from: https:\/\/www.gov.br\/saude\/pt-br\/canais-de-atendimento\/sala-de-imprensa\/notas-a-imprensa\/2023\/sobre-o-surto-de-febre-maculosa-em-campinas-sp [Last accessed: March7 2023]."},{"key":"e_1_3_6_26_1","unstructured":"Ministry of Health Brazil. Sobre o surto de febre maculosa em Campinas (SP); 2023b. Available from: https:\/\/www.gov.br\/saude\/pt-br\/canais-de-atendimento\/sala-de-imprensa\/notas-a-imprensa\/2023\/sobre-o-surto-de-febre-maculosa-em-campinas-sp [Last accessed: March7 2023]."},{"key":"e_1_3_6_27_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.23-0252"},{"key":"e_1_3_6_28_1","doi-asserted-by":"publisher","DOI":"10.1089\/vbz.2008.0092"},{"issue":"4","key":"e_1_3_6_29_1","article-title":"Special issue \u201cThe past and present threat of rickettsial diseases\u201d","volume":"5","author":"Paris DH","year":"2020","unstructured":"Paris DH. Special issue \u201cThe past and present threat of rickettsial diseases\u201d. Trop Med Infect Dis, 2020; 5(4).","journal-title":"Trop Med Infect Dis"},{"key":"e_1_3_6_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0000000000000298"},{"issue":"5","key":"e_1_3_6_31_1","article-title":"A spotted fever in Tobia, Colombia. 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Available from: http:\/\/epitools.ausvet.com.au [Last accessed: May8 2023]."},{"key":"e_1_3_6_37_1","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-45-3-589"},{"key":"e_1_3_6_38_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0003971"},{"key":"e_1_3_6_39_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40249-021-00893-6"},{"key":"e_1_3_6_40_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0010281"},{"key":"e_1_3_6_41_1","unstructured":"Tribin MCDG Rodriguez GEN Valderrama M. The Biosphere reserve of the Sierra Nevada de Santa Marta: A pioneer experience of a shared and co-ordinated management of a bioregion: Colombia. South-South Cooperation Programme: working papers. 1999."},{"key":"e_1_3_6_42_1","unstructured":"Vemaps. Colombia map 2019; 2019. 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