{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T06:18:37Z","timestamp":1791353917256,"version":"4.3.1"},"reference-count":63,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vector-Borne and Zoonotic Diseases"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Madariaga virus (MADV), a member of the eastern equine encephalitis virus (EEEV) complex, circulates in Latin America and exhibits distinct evolutionary and ecological features compared to the North American EEEV. While published data have shed light on MADV ecology, several key aspects remain unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>In this study, we compiled data on virus isolation, vector competence, and animal serology collected over six decades in Latin America to identify critical knowledge gaps on MADV transmission and ecology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Specific vertebrate animals serving as amplifying hosts and the mosquito species acting as enzootic and epizootic vectors have not yet been identified. Other aspects that remain unclear are the virus current geographic distribution, the role of equines as hosts in epizootic cycles, and the full impact of MADV on human health in endemic regions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The numerous knowledge gaps surrounding MADV, its widespread distribution in Latin America, and its potential to cause severe disease in animals and humans emphasize the urgent need for increased research efforts, heightened awareness, and intensified surveillance towards this potential emerging threat.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/vbz.2023.0162","type":"journal-article","created":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T08:16:11Z","timestamp":1715156171000},"page":"633-640","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Uncertainties Surrounding Madariaga Virus, a Member of the Eastern Equine Encephalitis Virus Complex"],"prefix":"10.1177","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1474-0889","authenticated-orcid":false,"given":"Tereza","family":"Magalhaes","sequence":"first","affiliation":[{"name":"Department of Entomology, Texas A&amp;M University, College Station, Texas, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel L.","family":"Hamer","sequence":"additional","affiliation":[{"name":"Department of Entomology, Texas A&amp;M University, College Station, Texas, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danilo","family":"de Carvalho-Leandro","sequence":"additional","affiliation":[{"name":"Department of Entomology, Texas A&amp;M University, College Station, Texas, USA."},{"name":"Col\u00e9gio de Aplica\u00e7\u00e3o, Universidade Federal de Pernambuco, Recife, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir M.L.","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Department of Pathology and Forensic Medicine, Universidade Federal do Cear\u00e1, Fortaleza, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Turell","sequence":"additional","affiliation":[{"name":"VectorID LLC, Frederick, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,10,7]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.11606\/issn.1678-4456.bjvras.2008.26685"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2007.76.293"},{"key":"e_1_3_4_4_1","first-page":"3","article-title":"Infec\u00e7\u00e3o humana pelo v\u00edrus \u201cleste\u201d da encefalite equina","volume":"3","author":"Alice FJ","year":"1956","unstructured":"Alice FJ. 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