{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T06:57:39Z","timestamp":1777877859392,"version":"3.51.4"},"reference-count":49,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vector-Borne and Zoonotic Diseases"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Spirometra mansoni<\/jats:italic>\n                      is a crucial zoonotic parasite. Its larvae are more harmful than adult worms due to their ability to migrate through the host\u2019s tissues and organs. Therefore, it is necessary to establish an animal model of spargana for observing pathological changes and exploring diagnostic techniques.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      In this study, we infected Kunming mice and cats without any pathogens by feeding sparganum (with the scolex and neck) in order to understand the infection cycle of\n                      <jats:italic toggle=\"yes\">S. mansoni<\/jats:italic>\n                      and explore the preservation host of sparganosis. The infection of\n                      <jats:italic toggle=\"yes\">S. mansoni<\/jats:italic>\n                      was determined by fecal detection and enzyme-linked immunosorbent assay (ELISA).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      In the model of cats, the eggs of\n                      <jats:italic toggle=\"yes\">S. mansoni<\/jats:italic>\n                      were found in the feces ten days after the infection. The serum-specific IgG antibodies against\n                      <jats:italic toggle=\"yes\">S. mansoni<\/jats:italic>\n                      were positive in experimental groups (mice and cats), and after sixty days, the S. mansoni worms isolated from experimental groups were collected.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      In conclusion, the experimental results show that mice and cats can be stably infected with S. mansoni through feeding sparganum (with the scolex and neck). The infection method of this study has the potential to establish a practical model for investigating the diagnostic process of\n                      <jats:italic toggle=\"yes\">S. mansoni<\/jats:italic>\n                      , laying the groundwork for application and development. ELISA was used to diagnose mice and cats infected with sparganosis mansoni, providing a case for non-invasive identification of animal sparganosis.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/vbz.2024.0051","type":"journal-article","created":{"date-parts":[[2024,10,25]],"date-time":"2024-10-25T04:34:43Z","timestamp":1729830883000},"page":"133-141","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Establishment of Animal Infection Model of\n                    <i>Spirometra Mansoni<\/i>\n                    and Identification of\n                    <i>Spirometra Mansoni<\/i>\n                    by Enzyme-Linked Immunosorbent Assay"],"prefix":"10.1177","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7791-0379","authenticated-orcid":false,"given":"Anqi","family":"Luo","sequence":"first","affiliation":[{"name":"Research Center for Parasites &amp; Vectors, College of Veterinary Medicine, Hunan Agricultural University, Changsha, China."},{"name":"Hunan Key Laboratory of Chinese Veterinary Medicine, Changsha, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuyu","family":"Chen","sequence":"additional","affiliation":[{"name":"Research Center for Parasites &amp; Vectors, College of Veterinary Medicine, Hunan Agricultural University, Changsha, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingye","family":"He","sequence":"additional","affiliation":[{"name":"YiYang Vocational &amp; Technical College, Yiyang, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoruo","family":"Tan","sequence":"additional","affiliation":[{"name":"Research Center for Parasites &amp; Vectors, College of Veterinary Medicine, Hunan Agricultural University, Changsha, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhikang","family":"Li","sequence":"additional","affiliation":[{"name":"Research Center for Parasites &amp; Vectors, College of Veterinary Medicine, Hunan Agricultural University, Changsha, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Liu","sequence":"additional","affiliation":[{"name":"Research Center for Parasites &amp; Vectors, College of Veterinary Medicine, Hunan Agricultural University, Changsha, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yisong","family":"Liu","sequence":"additional","affiliation":[{"name":"Research Center for Parasites &amp; Vectors, College of Veterinary Medicine, Hunan Agricultural University, Changsha, China."},{"name":"Hunan Key Laboratory of Chinese Veterinary Medicine, Changsha, China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,2,5]]},"reference":[{"issue":"1","key":"e_1_3_4_2_1","first-page":"280","article-title":"Laboratory production and maintenance of Spirometra erinacei spargana","volume":"35","author":"Apichat V","year":"2004","unstructured":"Apichat V, , Tuanchai S, , Paiboon S, et al. 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