{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T13:00:47Z","timestamp":1773925247486,"version":"3.50.1"},"reference-count":37,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Women's Health Reports"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Ovarian fibrothecoma is a rare benign sex cord-stromal ovarian tumor sorted under the thecoma-fibroma group. We present an analysis of clinical and laboratory findings and the radiological characteristic features of pathologically proven fibrothecomas in variable imaging modalities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective analysis was done for 88 patients with 90 pathologically proven ovarian fibrothecoma between January 2011 and December 2023 from our center\u2019s prospectively maintained database. All the patients underwent preoperative ultrasonography, computed tomography (CT), and magnetic resonance imaging (MRI) scans, clinical examinations, basic laboratory tests, and tumor markers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The results of Spearman\u2019s correlation revealed a statistically significant positive correlation between the largest tumor diameter and serum level. CA 125, the degree of ascites, and diffusion weighted imaging (DWI) signal intensity while the results of point biserial correlation revealed a statistically significant correlation of the largest tumor diameter with the presence of ascites, cystic changes, abdominal enlargement, surgery type, and border type. There were also statistically significantly higher hypoechoic lesions in the smaller tumor group (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.001) but not for isoechoic (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.099) and mixed (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.052). Regarding the MRI, there was a statistically significantly larger tumor diameter in T2 mixed-hyperintense versus hypointense (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.007) and intermediate (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.010) signal intensities.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Fibrothecoma showed a statistically significant positive correlation between the largest tumor diameter with serum level CA 125 and the amount of ascites. On imaging, it shows mild enhancement in both CT and MRI, with a statistically significant positive correlation of the largest tumor diameter with T2 and DWI signal intensity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/whr.2024.0153","type":"journal-article","created":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T20:40:08Z","timestamp":1769028008000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Fibrothecoma of the Ovary; Clinical and Imaging Characteristics"],"prefix":"10.1177","volume":"6","author":[{"given":"Gehad Ahmad","family":"Saleh","sequence":"first","affiliation":[{"name":"Radiology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Hamdy","sequence":"additional","affiliation":[{"name":"Surgical Oncology Department, Oncology Center, Mansoura University, Mansoura, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dina","family":"Ragab","sequence":"additional","affiliation":[{"name":"Medical Intern, Mansoura University Hospitals, Mansoura, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bassante","family":"Farouk","sequence":"additional","affiliation":[{"name":"Medical Intern, Mansoura University Hospitals, Mansoura, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mennatalla Mahmoud","family":"Allam","sequence":"additional","affiliation":[{"name":"Medical Intern, Mansoura University Hospitals, Mansoura, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rawan","family":"Abo Asy","sequence":"additional","affiliation":[{"name":"Medical Intern, Mansoura University Hospitals, Mansoura, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatmaelzahraa A.","family":"Denewar","sequence":"additional","affiliation":[{"name":"Radiology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Ezat","sequence":"additional","affiliation":[{"name":"Surgical Oncology Department, Oncology Center, Mansoura University, Mansoura, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,3,25]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20210790"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12013-014-0288-7"},{"issue":"10","key":"e_1_3_6_4_2","doi-asserted-by":"crossref","first-page":"2631","DOI":"10.1002\/cncr.11345","article-title":"Pathology and classification of ovarian tumors","volume":"97","author":"Chen VW","year":"2003","unstructured":"Chen VW, , Ruiz B, , Killeen JL, et al. 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