{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T08:47:16Z","timestamp":1773305236887,"version":"3.50.1"},"reference-count":29,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Advances in Wound Care"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To compare the tolerability and mechanical tensile strength of acute skin wounds closed with nylon suture plus a novel suture bridge device (SBD) with acute skin wounds closed with nylon suture in a porcine model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Approach:<\/jats:title>\n                    <jats:p>\n                      Four Yucatan pigs each received 12 4.5\u2009cm full-thickness incisions that were closed with 1 of 4 options: Suture bridge with nylon, suture bridge with nylon and subdermal polyglactin, nylon simple interrupted, and nylon simple interrupted with subdermal polyglactin. Epithelial reaction, inflammation, and scarring were examined histologically at days 10 and 42. Wound strength was examined mechanically at days 10 and 42 on\n                      <jats:italic toggle=\"yes\">ex vivo<\/jats:italic>\n                      wounds from euthanized pigs.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Histopathology in the suture entry\/exit planes showed greater dermal inflammation with a simple interrupted nylon suture retained for 42 days compared with the SBD retained for 42 days (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.03). While tensile wound strength in the device and suture groups were similar at day 10, wounds closed with the devices were nearly 8 times stronger at day 42 compared with day 10 (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Innovation:<\/jats:title>\n                    <jats:p>A novel SBD optimized for cutaneous wound closure that protects the skin surface from suture strands, forms a protective bridge over the healing wound edges, and knotlessly clamps sutures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This study suggests that the use of a SBD increases the tolerability of nylon sutures in porcine acute skin wound closures allowing for prolonged mechanical support of the wound. For slow healing wounds, this may prevent skin wound disruption, such as edge necrosis and dehiscence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/wound.2017.0777","type":"journal-article","created":{"date-parts":[[2018,3,29]],"date-time":"2018-03-29T11:39:27Z","timestamp":1522323567000},"page":"177-184","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Comparing the Tolerability of a Novel Wound Closure Device Using a Porcine Wound Model"],"prefix":"10.1177","volume":"7","author":[{"given":"Katy L.","family":"Townsend","sequence":"first","affiliation":[{"name":"Oregon State University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jen","family":"Akeroyd","sequence":"additional","affiliation":[{"name":"JULVIA\u2122 Technologies, Inc."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duncan S.","family":"Russell","sequence":"additional","affiliation":[{"name":"Oregon State University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jamie J.","family":"Kruzic","sequence":"additional","affiliation":[{"name":"School of Mechanical and Manufacturing Engineering","place":["Australia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bria L.","family":"Robertson","sequence":"additional","affiliation":[{"name":"Oregon State University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Lear","sequence":"additional","affiliation":[{"name":"JULVIA\u2122 Technologies, Inc."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,6,1]]},"reference":[{"key":"e_1_3_4_2_2","unstructured":"Center for Health Statistics N. Number rate and standard error of all-listed surgical and nonsurgical procedures for discharges from short-stay hospitals by selected procedure categories: United States 2010. 2010. www.cdc.gov\/nchs\/data\/nhds\/4procedures\/2010pro4_numberrate.pdf (last accessed September30 2017)."},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2077.123395"},{"key":"e_1_3_4_4_2","article-title":"Tissue adhesives for closure of surgical incisions","volume":"28","author":"Dumville JC","year":"2014","unstructured":"Dumville JC, , Coulthard P, , Worthington HV, et al. Tissue adhesives for closure of surgical incisions. Cochrane Database Syst Rev, 2014; 28:CD004287.","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c1199"},{"key":"e_1_3_4_6_2","first-page":"145","article-title":"Octyl-2-cyanoacrylate adhersive for skin closure: eight years experience","volume":"29","author":"Grimaldi L","year":"2015","unstructured":"Grimaldi L, , Cuomo R, , Brandi C, , Botteri G, , D'Aniello C. Octyl-2-cyanoacrylate adhersive for skin closure: eight years experience. In Vivo, 2015; 29:145\u2013148.","journal-title":"In Vivo"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-010-1450-0"},{"key":"e_1_3_4_8_2","volume-title":"Cochrane Database of Systematic Reviews","author":"Biancari F","year":"2010","unstructured":"Biancari F, , Tiozzo V. Staples versus sutures for closing leg wounds after vein graft harvesting for coronary artery bypass surgery. In: Biancari F, ed. Cochrane Database of Systematic Reviews. Chichester, UK: John Wiley & Sons, Ltd.; 2010:CD008057."},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000222235.19796.f4"},{"key":"e_1_3_4_10_2","unstructured":"Hunter JG Martin E Dawson LK Baumhauer JF. The most common patient safety problems in elective foot and ankle orthopaedic surgery. www.aofas.org\/PRC\/meeting\/Documents\/TheMostCommonPatientSafetyProb.pdf (last accessed September30 2017)."},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.2016.25.7.377"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2004.05.276"},{"key":"e_1_3_4_13_2","unstructured":"Agency for Healthcare Research and Quality. AHRQ\u2014Quality Indicators. www.qualityindicators.ahrq.gov\/Modules\/psi_resources.aspx (last accessed October13 2017)."},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-26027-5.00013-9"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-196502000-00019"},{"key":"e_1_3_4_16_2","doi-asserted-by":"crossref","first-page":"e10","DOI":"10.1097\/GOX.0b013e31828ff9f4","article-title":"The role of wound healing and its everyday application in plastic surgery: a practical perspective and systematic review","volume":"1","author":"Ireton JE","year":"2013","unstructured":"Ireton JE, , Unger JG, , Rohrich RJ. The role of wound healing and its everyday application in plastic surgery: a practical perspective and systematic review. Plast Reconstr Surg Glob Open, 2013; 1:pii: e10\u2013e19.","journal-title":"Plast Reconstr Surg Glob Open"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-475x.2000.00511.x"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2016.06.033"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jccw.2014.03.001"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1177\/0022034509359125"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/JDN.0000000000000274"},{"key":"e_1_3_4_22_2","first-page":"27","article-title":"Pressure necrosis is the primary cause of wound dehiscence","volume":"28","author":"Bartlett LC","year":"1985","unstructured":"Bartlett LC. Pressure necrosis is the primary cause of wound dehiscence. Can J Surg, 1985; 28:27\u201330.","journal-title":"Can J Surg"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2012.05.012"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2006.02.003"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1177\/0300985811402846"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-07418-6.00010-1"},{"key":"e_1_3_4_27_2","doi-asserted-by":"publisher","DOI":"10.1177\/1090820X10395010"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900060114"},{"key":"e_1_3_4_29_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-197009000-00008"},{"key":"e_1_3_4_30_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-475X.2008.00436.x"}],"container-title":["Advances in Wound Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/wound.2017.0777","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/wound.2017.0777","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/wound.2017.0777","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T14:17:47Z","timestamp":1773238667000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/wound.2017.0777"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1089\/wound.2017.0777"],"URL":"https:\/\/doi.org\/10.1089\/wound.2017.0777","relation":{},"ISSN":["2162-1918","2162-1934"],"issn-type":[{"value":"2162-1918","type":"print"},{"value":"2162-1934","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6]]}}}