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Their etiologies determine the characteristics and extent of the injury. The timing of subsequent surgical intervention and wound healing optimization after lower extremity trauma are integral to successful perioperative lower extremity wound management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Recent Advances:<\/jats:title>\n                    <jats:p>Managing trauma to the lower extremities uses a multidisciplinary surgical approach. The objective of this review is to summarize lower limb trauma assessment, advancements in lower extremity trauma management, and the clinical applications of advanced wound care in lower limb traumatic wounds. The advent of lower limb reconstruction and the development of advanced wound care modalities have helped to improve the management of these complex injuries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Critical Issues:<\/jats:title>\n                    <jats:p>The extensive involvement of bone, soft tissues, nerves, and blood vessels of severe lower extremity trauma wounds presents a challenge for clinicians in both the acute care setting and during patient rehabilitation. If not properly managed, these injuries may be subject to a decline in limb function and may possibly result in limb loss. To reveal developing limb-threatening conditions, serial examinations should be performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Future Directions:<\/jats:title>\n                    <jats:p>The majority of lower limb traumatic wound will benefit from the perioperative administration of an appropriate negative pressure wound therapy (NPWT)-based system, which can help to promote granulation tissue and remove wound exudate before definitive closure and\/or reconstruction. NPWT should be included as an important adjunct in the surgical management of lower limb traumatic wounds.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/wound.2023.0133","type":"journal-article","created":{"date-parts":[[2024,7,13]],"date-time":"2024-07-13T09:13:11Z","timestamp":1720861991000},"page":"327-343","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Lower Extremity Traumatic Wound Management: Relative Significance of Negative Pressure Wound Therapy in the Orthopedic Setting"],"prefix":"10.1177","volume":"14","author":[{"given":"Evania","family":"Lok","sequence":"first","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Austin Health, Melbourne, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Oe","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Austin Health, Melbourne, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7332-627X","authenticated-orcid":false,"given":"Sally","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery, Austin Health, Melbourne, Australia."},{"name":"Department of Surgery (Austin Precinct), University of Melbourne, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,6,30]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.21.00632"},{"key":"e_1_3_5_3_2","first-page":"339","article-title":"Consequences and costs of lower extremity injuries","volume":"48","author":"Dischinger PC","year":"2004","unstructured":"Dischinger PC, , Read KM, , Kufera JA, et al. 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