{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T02:30:46Z","timestamp":1793068246622,"version":"4.5.0"},"reference-count":27,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Advances in Wound Care"],"published-print":{"date-parts":[[2026,4,1]]},"abstract":"\n Object:<\/jats:title>\n \n The aim of this study was to compare the long-term effects of fractional carbon dioxide (CO\n 2<\/jats:sub>\n ) laser treatment with traditional therapy on surgical scars by analyzing and comparing observational indicators.\n <\/jats:p>\n <\/jats:sec>\n \n Approach:<\/jats:title>\n \n A randomized controlled trial was conducted on 116 patients who received scar treatment in our hospital, of which 58 patients received fractional CO\n 2<\/jats:sub>\n laser treatment, and 58 patients received injection treatment. The outcome measures comprised the Vancouver Scar Scale (VSS) and the Patient and Observer Scar Assessment Scale (POSAS). The observation intervals occur at specific times. Evaluated at 6 months of follow-up, the outcome was blinded, on-site evaluation using the dermatological appearance scale (DAS) and visual analog scale (VAS).\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Patients in the fractional carbon-dioxide laser (CO\n 2<\/jats:sub>\n FL) group rated better than those in the injection group in the POSAS, VSS, DAS, and VAS scores (\n p<\/jats:italic>\n < 0.05). The therapeutic efficacy and patients\u2019 satisfaction of the research group were superior to those in the control group.\n <\/jats:p>\n <\/jats:sec>\n \n Innovation:<\/jats:title>\n \n Scars following surgical procedures can be treated in a variety of methods, but there is no consensus on the best method. CO\n 2<\/jats:sub>\n FL has exhibited safety and is more effective than traditional injection treatments for surgical scars. It is a worthwhile approach to consider in clinical treatment.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n \n This study demonstrates that CO\n 2<\/jats:sub>\n FL achieves more significant long-term results in surgical scars, including improved scar appearance, safety, and patient satisfaction.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1089\/wound.2024.0213","type":"journal-article","created":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T10:00:48Z","timestamp":1737972048000},"page":"208-217","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Treatment of Surgical Scars with Fractional Carbon Dioxide (CO\n 2<\/sub>\n ) Laser: A Randomized Controlled Trial"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-3743-5181","authenticated-orcid":false,"given":"Liang","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Dermatology, The Second Affiliated Hospital of Wannan Medic-al College, Wuhu, Anhui, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Oncology, Bengbu Third People\u2019s Hospital Affiliated to Beng-bu Medical University, Bengbu, Anhui, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiu Yu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Electrocardiology, The Second Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Wanna-n Medical College, Wuhu, Anhui, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin Qi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, The Second Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao Ming","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The Second Affiliated Hospital of Wannan Medic-al College, Wuhu, Anhui, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,4,8]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-019-02830-4"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.17076"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2004.1475"},{"issue":"8","key":"e_1_3_4_5_2","first-page":"e66806","article-title":"A comparative analysis of the advances in scar reduction: Techniques, technologies, and efficacy in plastic surgery","volume":"16","author":"Meretsky CR","year":"2024","unstructured":"Meretsky CR, , Polychronis A, , Schiuma AT. A comparative analysis of the advances in scar reduction: Techniques, technologies, and efficacy in plastic surgery. Cureus Journal of Medical Science, 2024; 16(8):e66806.","journal-title":"Cureus Journal of Medical Science"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1089\/wound.2020.1348"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-024-03976-6"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-020-02135-5"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/dth.13084"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/jbcr\/iraa130"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/dsu.12365"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.15276"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15497"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2011.02008.x"},{"issue":"4","key":"e_1_3_4_15_2","first-page":"358","article-title":"Application of fractional laser in the treatment of scars","volume":"107","author":"Szczepanik-Kulak P","year":"2020","unstructured":"Szczepanik-Kulak P, , Michalska-Jakubus M, , Niewiedziol M, et al. Application of fractional laser in the treatment of scars. Przeglad Dermatologiczny, 2020; 107(4):358\u2013377.","journal-title":"Przeglad Dermatologiczny"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2022.12.017"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10492.x"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.16348"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2021.08.010"},{"issue":"4","key":"e_1_3_4_20_2","first-page":"e58358","article-title":"Prospective evaluation of fractional carbon dioxide laser treatment of mature burn scars, post-traumatic scars, and post-acne scars","volume":"16","author":"Sharma Y","year":"2024","unstructured":"Sharma Y, , Jain P, , Gottam SB, et al. Prospective evaluation of fractional carbon dioxide laser treatment of mature burn scars, post-traumatic scars, and post-acne scars. 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