{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T14:30:26Z","timestamp":1779114626276,"version":"3.51.4"},"reference-count":32,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T00:00:00Z","timestamp":1777248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Advances in Wound Care"],"published-print":{"date-parts":[[2026,5,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The risk of pressure injuries (PIs) is increasing in Japan, where an aging population imposes substantial health care burdens.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Approach:<\/jats:title>\n                    <jats:p>This retrospective cohort study utilizing the Shizuoka Kokuho Database evaluated factors associated with PI development in hospitalized patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>An analysis of over 546,000 patients aged \u226565 years from 2012 to 2022 identified 6,372 PI cases. Cox regression analyses revealed that male sex (hazard ratio [HR] 1.32, 95% confidence interval [CI]: 1.25\u20131.39), advanced age (HR 8.54, 95% CI: 7.40\u20139.87 for \u226595 years vs. 65\u201369 years) and comorbidities such as neurological disorders (HR 1.87, 95% CI: 1.72\u20132.04), dementia (HR 1.69, 95% CI: 1.59\u20131.80), and congestive heart failure (HR 1.19, 95% CI: 1.12\u20131.27) were associated with increased PI risks. Conversely, antihyperlipidemic drugs may be associated with a lower PI risk (HR 0.69, 95% CI: 0.65\u20130.74). Due to data limitations, factors such as nutritional status, mobility, and caregiver support could not be evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Innovation:<\/jats:title>\n                    <jats:p>This study is the first in Japan to leverage big data to identify high-risk groups for PIs, particularly among elderly individuals with specific comorbidities. This approach offers actionable insights into PI management, potentially enhancing care strategies and preventive guidelines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Male sex, advanced age, and comorbidities, including neurological disorders, dementia, psychosis, and congestive heart failure, were identified as primary PI risk factors. Conversely, antihyperlipidemic drug use may be associated with a lower PI risk. These findings highlight the need for comprehensive, targeted prevention strategies to reduce the risk of PI in elderly hospitalized patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/wound.2024.0256","type":"journal-article","created":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T21:04:11Z","timestamp":1742245451000},"page":"289-298","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["The Shizuoka Study of a Population-Based Retrospective Cohort for the Evaluation of Risk of Pressure Injury in the Elderly"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5809-0040","authenticated-orcid":false,"given":"Hideo","family":"Hashizume","sequence":"first","affiliation":[{"name":"Department of Future Wellness (endowed by TAICA Co.), Public Health Research Center, Shizuoka Graduate University of Public Health, Shizuoka, Japan."},{"name":"Department of Dermatology, Iwata City Hospital, Iwata, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ammi","family":"Matsuura","sequence":"additional","affiliation":[{"name":"Department of Future Wellness (endowed by TAICA Co.), Public Health Research Center, Shizuoka Graduate University of Public Health, Shizuoka, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiki","family":"Miyachi","sequence":"additional","affiliation":[{"name":"Shizuoka Graduate University of Public Health, Shizuoka, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,4,27]]},"reference":[{"key":"e_1_3_6_2_2","unstructured":"Ministry of Health Labour and Welfare. 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