{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T12:31:35Z","timestamp":1790771495862,"version":"4.1.0"},"reference-count":31,"publisher":"American Society for Cell Biology (ASCB)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["MBoC"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:p> USP19 deubiquitinating enzyme has two isoforms, cytoplasmic and endoplasmic reticulum (ER) localized. The ER-localized isoform specifically suppresses muscle cell differentiation in vitro and appears to do so by inhibiting the unfolded-protein response that occurs during such differentiation. In vivo, loss of USP19 promotes muscle regeneration following injury. <\/jats:p>","DOI":"10.1091\/mbc.e14-06-1129","type":"journal-article","created":{"date-parts":[[2015,1,8]],"date-time":"2015-01-08T07:14:24Z","timestamp":1420701264000},"page":"913-923","source":"Crossref","is-referenced-by-count":48,"title":["USP19 deubiquitinating enzyme inhibits muscle cell differentiation by suppressing unfolded-protein response signaling"],"prefix":"10.1091","volume":"26","author":[{"given":"Benjamin","family":"Wiles","sequence":"first","affiliation":[{"name":"Polypeptide Laboratory, McGill University and McGill University Health Centre Research Institute, Montreal, QC H3A OC7, Canada"},{"name":"Department of Medicine, McGill University and McGill University Health Centre Research Institute, Montreal, QC H3A OC7, Canada"},{"name":"Department of Biochemistry, McGill University and McGill University Health Centre Research Institute, Montreal, QC H3A OC7, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Miao","sequence":"additional","affiliation":[{"name":"Polypeptide Laboratory, McGill University and McGill University Health Centre Research Institute, Montreal, QC H3A OC7, Canada"},{"name":"Department of Medicine, McGill University and McGill University Health Centre Research Institute, Montreal, QC H3A OC7, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin","family":"Coyne","sequence":"additional","affiliation":[{"name":"Polypeptide Laboratory, McGill University and McGill University Health Centre Research Institute, Montreal, QC H3A OC7, Canada"},{"name":"Department of Medicine, McGill University and McGill University Health Centre Research Institute, Montreal, QC H3A OC7, Canada"},{"name":"Department of Biochemistry, McGill University and McGill University Health Centre Research Institute, Montreal, QC H3A OC7, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Larose","sequence":"additional","affiliation":[{"name":"Polypeptide Laboratory, McGill University and McGill University Health Centre Research Institute, Montreal, QC H3A OC7, Canada"},{"name":"Department of Medicine, McGill University and McGill University Health Centre Research Institute, Montreal, QC H3A OC7, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrey V.","family":"Cybulsky","sequence":"additional","affiliation":[{"name":"Department of Medicine, McGill University and McGill University Health Centre Research Institute, Montreal, QC H3A OC7, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon S.","family":"Wing","sequence":"additional","affiliation":[{"name":"Polypeptide Laboratory, McGill University and McGill University Health Centre Research Institute, Montreal, QC H3A OC7, Canada"},{"name":"Department of Medicine, McGill University and McGill University Health Centre Research Institute, Montreal, QC H3A OC7, Canada"},{"name":"Department of Biochemistry, McGill University and McGill University Health Centre Research Institute, Montreal, QC H3A OC7, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1076","reference":[{"key":"B1","doi-asserted-by":"crossref","first-page":"C579","DOI":"10.1152\/ajpcell.1997.273.2.C579","volume":"273","author":"Allen DL","year":"1997","journal-title":"Am J Physiol"},{"key":"B2","doi-asserted-by":"crossref","first-page":"1962","DOI":"10.1074\/jbc.M111.305615","volume":"287","author":"Altun M","year":"2012","journal-title":"J Biol Chem"},{"key":"B3","first-page":"4","author":"Bentzinger CF","year":"2012","journal-title":"Cold Spring Harbor Perspect Biol"},{"key":"B4","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1126\/science.1065874","volume":"294","author":"Bodine SC","year":"2001","journal-title":"Science"},{"key":"B5","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/j.molcel.2010.09.029","volume":"40","author":"Boutet SC","year":"2010","journal-title":"Mol Cell"},{"key":"B6","doi-asserted-by":"crossref","first-page":"99","DOI":"10.3389\/fphys.2014.00099","volume":"5","author":"Brooks NE","year":"2014","journal-title":"Frontiers Physiol"},{"key":"B31","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1152\/physrev.00019.2003","volume":"84","author":"Charg\u00e9 SBP","year":"2004","journal-title":"Physiol Rev"},{"key":"B7","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0003-2697(87)90021-2","volume":"162","author":"Chomczynski P","year":"1987","journal-title":"Anal Biochem"},{"key":"B8","doi-asserted-by":"crossref","first-page":"E693","DOI":"10.1152\/ajpendo.00281.2004","volume":"288","author":"Combaret L","year":"2005","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"B9","doi-asserted-by":"crossref","first-page":"14440","DOI":"10.1073\/pnas.251541198","volume":"98","author":"Gomes MD","year":"2001","journal-title":"Proc Natl Acad Sci USA"},{"key":"B10","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1038\/embor.2009.69","volume":"10","author":"Hassink GC","year":"2009","journal-title":"EMBO Rep"},{"key":"B11","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1038\/364501a0","volume":"364","author":"Hasty P","year":"1993","journal-title":"Nature"},{"key":"B12","doi-asserted-by":"crossref","first-page":"4821","DOI":"10.1172\/JCI68523","volume":"123","author":"He WA","year":"2013","journal-title":"J Clin Invest"},{"key":"B13","doi-asserted-by":"crossref","first-page":"5928","DOI":"10.1093\/hmg\/ddu317","volume":"23","author":"Hyrskyluoto A","year":"2014","journal-title":"Hum Mol Genet"},{"key":"B14","doi-asserted-by":"crossref","first-page":"2715","DOI":"10.1016\/j.febslet.2009.07.033","volume":"583","author":"Jogo M","year":"2009","journal-title":"FEBS Lett"},{"key":"B15","doi-asserted-by":"crossref","first-page":"3510","DOI":"10.1074\/jbc.M113.538934","volume":"289","author":"Lee JG","year":"2014","journal-title":"J Biol Chem"},{"key":"B16","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1002\/jcb.23151","volume":"112","author":"Liu Q","year":"2011","journal-title":"J Cell Biochem"},{"key":"B17","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","volume":"25","author":"Livak KJ","year":"2001","journal-title":"Methods"},{"key":"B18","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1128\/MCB.00329-08","volume":"29","author":"Lu Y","year":"2009","journal-title":"Mol Cell Biol"},{"key":"B19","doi-asserted-by":"crossref","first-page":"35380","DOI":"10.1074\/jbc.M111.282020","volume":"286","author":"Mei Y","year":"2011","journal-title":"J Biol Chem"},{"key":"B20","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.yexcr.2014.07.025","volume":"328","author":"Nakamura N","year":"2014","journal-title":"Exp Cell Res"},{"key":"B21","doi-asserted-by":"crossref","first-page":"2994","DOI":"10.1096\/fj.06-6408com","volume":"21","author":"Nakanishi K","year":"2007","journal-title":"FASEB J"},{"key":"B22","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1083\/jcb.200412024","volume":"169","author":"Nakanishi K","year":"2005","journal-title":"J Cell Biol"},{"key":"B23","first-page":"1","author":"Ogawa M","year":"2012","journal-title":"Br J Nutr"},{"key":"B24","doi-asserted-by":"crossref","first-page":"41455","DOI":"10.1074\/jbc.M111.276824","volume":"286","author":"Ogawa M","year":"2011","journal-title":"J Biol Chem"},{"key":"B25","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1016\/0092-8674(93)90621-V","volume":"75","author":"Rudnicki MA","year":"1993","journal-title":"Cell"},{"key":"B26","doi-asserted-by":"crossref","first-page":"4294","DOI":"10.1111\/febs.12253","volume":"280","author":"Schiaffino S","year":"2013","journal-title":"FEBS J"},{"key":"B30","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/S0092-8674(00)00066-0","volume":"102","author":"Seale P","year":"2000","journal-title":"Cell"},{"key":"B27","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1249\/MSS.0b013e3181a6470b","volume":"41","author":"Siu PM","year":"2009","journal-title":"Med Sci Sports Exercise"},{"key":"B28","doi-asserted-by":"crossref","first-page":"E1283","DOI":"10.1152\/ajpendo.00409.2009","volume":"297","author":"Sundaram P","year":"2009","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"B29","doi-asserted-by":"crossref","first-page":"2847","DOI":"10.1074\/jbc.M411346200","volume":"280","author":"Tintignac LA","year":"2005","journal-title":"J Biol Chem"}],"container-title":["Molecular Biology of the Cell"],"original-title":[],"language":"en","deposited":{"date-parts":[[2019,7,14]],"date-time":"2019-07-14T13:47:48Z","timestamp":1563112068000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.molbiolcell.org\/doi\/10.1091\/mbc.E14-06-1129"}},"subtitle":[],"editor":[{"given":"Jeffrey L.","family":"Brodsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2015,3]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.1091\/mbc.E14-06-1129"],"URL":"https:\/\/doi.org\/10.1091\/mbc.e14-06-1129","relation":{},"ISSN":["1059-1524","1939-4586"],"issn-type":[{"value":"1059-1524","type":"print"},{"value":"1939-4586","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3]]}}}