{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:42:47Z","timestamp":1753875767425,"version":"3.41.2"},"reference-count":52,"publisher":"American Society for Cell Biology (ASCB)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["MBoC"],"published-print":{"date-parts":[[2023,5,1]]},"abstract":"<jats:p> While determining the key factors that characterize cells bearing unrepaired double-strand breaks (DSBs), we discovered ATM-dependent phosphorylation of CHD7 at unrepaired DSBs. CHD7 is known to be an indispensable transcription factor in early development. This indicates that morphogenesis and DSB repair are coupled in the development of heart and neurosensory organs. <\/jats:p>","DOI":"10.1091\/mbc.e22-10-0450","type":"journal-article","created":{"date-parts":[[2023,3,8]],"date-time":"2023-03-08T16:57:30Z","timestamp":1678294650000},"source":"Crossref","is-referenced-by-count":1,"title":["ATM\u2013dependent phosphorylation of CHD7 regulates morphogenesis-coupled DSB stress response in fetal radiation exposure"],"prefix":"10.1091","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9029-9813","authenticated-orcid":false,"given":"Asao","family":"Noda","sequence":"first","affiliation":[{"name":"Department of Molecular Biosciences, Radiation Effects Research Foundation, Minami-ku, Hiroshima City, Hiroshima 732-0815, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaori","family":"Muramoto","sequence":"additional","affiliation":[{"name":"Department of Molecular Biosciences, Radiation Effects Research Foundation, Minami-ku, Hiroshima City, Hiroshima 732-0815, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuji","family":"Mishima","sequence":"additional","affiliation":[{"name":"Department of Molecular Biosciences, Radiation Effects Research Foundation, Minami-ku, Hiroshima City, Hiroshima 732-0815, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1076","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-021-02788-6"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1038\/nature08733"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.tig.2015.05.009"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddi375"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2019.09.024"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1002\/bies.950190905"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1038\/ng.825"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-86919-3"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms14758"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M809158200"},{"key":"B11","volume-title":"Radiobiology for the Radiobiologist","author":"Hall EJ","year":"1994","edition":"4"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2536-x"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1007\/s00335-006-0107-6"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1126\/science.1150034"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.2010.01446.x"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddp112"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0507722102"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddt610"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq387"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1001010"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1126\/science.1140321"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1038\/d41586-022-00413-y"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1038\/embor.2009.21"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10913"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1093\/jrr\/rrx074"},{"key":"B27","first-page":"5280","volume":"125","author":"Noda A","year":"2012","journal-title":"J Cell Sci"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrgentox.2010.12.010"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1186\/s41021-015-0018-4"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0136041"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1203230"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1080\/095530098141285"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1038\/nm0596-577"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1080\/095530098141555"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1269\/jrr.32.SUPPLEMENT_249"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.31584"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2015.06.017"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-19502-5"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.2307\/3571860"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1101\/gr.086983.108"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1001023"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-014-1444-2"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.24156"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1242\/dev.121.12.4057"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1038\/nature13585"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1038\/ng1407"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2113233119"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.23.7.2556-2563.2003"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1172\/JCI83408"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.21.11472"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2005222117"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-74537-4"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.33323"}],"container-title":["Molecular Biology of the Cell"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T18:00:30Z","timestamp":1682359230000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.molbiolcell.org\/doi\/10.1091\/mbc.E22-10-0450"}},"subtitle":[],"editor":[{"given":"Dennis","family":"Discher","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2023,5,1]]},"references-count":52,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5,1]]}},"alternative-id":["10.1091\/mbc.E22-10-0450"],"URL":"https:\/\/doi.org\/10.1091\/mbc.e22-10-0450","relation":{},"ISSN":["1059-1524","1939-4586"],"issn-type":[{"type":"print","value":"1059-1524"},{"type":"electronic","value":"1939-4586"}],"subject":[],"published":{"date-parts":[[2023,5,1]]},"article-number":"ar39"}}