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Thus it is an urgent task for developing high-efficiency, low-toxicity and targeted drugs according to pathogenesis of coronavirus. In this paper, a novel disease-related compound identification model\u2013based capsule network (CapsNet) is proposed. According to pneumonia-related keywords, the prescriptions and active components related to the pharmacological mechanism of disease are collected and extracted in order to construct training set. The features of each component are extracted as the input layer of capsule network. CapsNet is trained and utilized to identify the pneumonia-related compounds in Qingre Jiedu injection. The experiment results show that CapsNet can identify disease-related compounds more accurately than SVM, RF, gcForest and forgeNet.<\/jats:p>","DOI":"10.1093\/bib\/bbab462","type":"journal-article","created":{"date-parts":[[2021,10,10]],"date-time":"2021-10-10T11:06:58Z","timestamp":1633864018000},"source":"Crossref","is-referenced-by-count":44,"title":["Active disease-related compound identification based on capsule network"],"prefix":"10.1093","volume":"23","author":[{"given":"Bin","family":"Yang","sequence":"first","affiliation":[{"name":"School of Information science and Engineering, Zaozhuang University, Zaozhuang, China 277160"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1471-5432","authenticated-orcid":false,"given":"Wenzheng","family":"Bao","sequence":"additional","affiliation":[{"name":"School of Information and Electrical Engineering, Xuzhou University of Technology, Xuzhou, China 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