{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T22:53:38Z","timestamp":1791759218651,"version":"4.3.4"},"reference-count":47,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T00:00:00Z","timestamp":1672099200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100003392","name":"Natural Science Foundation of Fujian Province","doi-asserted-by":"publisher","award":["2021J05260"],"award-info":[{"award-number":["2021J05260"]}],"id":[{"id":"10.13039\/501100003392","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Fujian Provincial Department of Education Project-Young and Middle-aged Teacher Education Project","award":["JAT200474"],"award-info":[{"award-number":["JAT200474"]}]},{"name":"Ministry of Education of China project of Humanities and Social Sciences","award":["21YJC910011"],"award-info":[{"award-number":["21YJC910011"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,19]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Viral infection involves a large number of protein\u2013protein interactions (PPIs) between the virus and the host, and the identification of these PPIs plays an important role in revealing viral infection and pathogenesis. Existing computational models focus on predicting whether human proteins and viral proteins interact, and rarely take into account the types of diseases associated with these interactions. Although there are computational models based on a matrix and tensor decomposition for predicting multi-type biological interaction relationships, these methods cannot effectively model high-order nonlinear relationships of biological entities and are not suitable for integrating multiple features. To this end, we propose a novel computational framework, LTDSSL, to determine human\u2013virus PPIs under different disease types. LTDSSL utilizes logistic functions to model nonlinear associations, sets importance levels to emphasize the importance of observed interactions and utilizes sparse subspace learning of multiple features to improve model performance. Experimental results show that LTDSSL has better predictive performance for both new disease types and new triples than the state-of-the-art methods. In addition, the case study further demonstrates that LTDSSL can effectively predict human-viral PPIs under various disease types.<\/jats:p>","DOI":"10.1093\/bib\/bbac604","type":"journal-article","created":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T10:54:25Z","timestamp":1672138465000},"source":"Crossref","is-referenced-by-count":8,"title":["Logistic tensor decomposition with sparse subspace learning for prediction of multiple disease types of human\u2013virus protein\u2013protein interactions"],"prefix":"10.1093","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6044-1439","authenticated-orcid":false,"given":"Yingjun","family":"Ma","sequence":"first","affiliation":[{"name":"School of Mathematics and Statistics, Xiamen University of Technology , Xiamen, 361024 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junjiang","family":"Zhong","sequence":"additional","affiliation":[{"name":"School of Mathematics and Statistics, Xiamen University 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