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These constituents communicate with one another to induce changes in the host\u2019s mood, cognition and demeanor. Knowledge concerning the regulation of the host central nervous system by gut microbiota is fragmented and mostly confined to disorganized or semi-structured unrestricted texts. Such a format hinders the exploration and comprehension of unknown territories or the further advancement of artificial intelligence systems. Hence, we collated crucial information by scrutinizing an extensive body of literature, amalgamated the extant knowledge of the microbiota\u2013gut\u2013brain axis and depicted it in the form of a knowledge graph named MMiKG, which can be visualized on the GraphXR platform and the Neo4j database, correspondingly. By merging various associated resources and deducing prospective connections between gut microbiota and the central nervous system through MMiKG, users can acquire a more comprehensive perception of the pathogenesis of mental disorders and generate novel insights for advancing therapeutic measures. As a free and open-source platform, MMiKG can be accessed at http:\/\/yangbiolab.cn:8501\/ with no login requirement.<\/jats:p>","DOI":"10.1093\/bib\/bbad340","type":"journal-article","created":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T08:05:02Z","timestamp":1694505902000},"source":"Crossref","is-referenced-by-count":16,"title":["MMiKG: a knowledge graph-based platform for path mining of microbiota\u2013mental diseases interactions"],"prefix":"10.1093","volume":"24","author":[{"given":"Haoran","family":"Sun","sequence":"first","affiliation":[{"name":"School of Medical Imaging, Fujian Medical University , Fuzhou 350122 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoqi","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Bioinformatics , Fujian Key Laboratory of Medical Bioinformatics, , Fuzhou 350122 , China"},{"name":"School of Medical Technology and Engineering, Fujian Medical University , Fujian Key Laboratory of 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