{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T01:12:50Z","timestamp":1774660370570,"version":"3.50.1"},"reference-count":87,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T00:00:00Z","timestamp":1726704000000},"content-version":"vor","delay-in-days":56,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Italian Ministry of Health","doi-asserted-by":"publisher","award":["J47G22000300001"],"award-info":[{"award-number":["J47G22000300001"]}],"id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Italian NRRP","award":["IR0000031"],"award-info":[{"award-number":["IR0000031"]}]},{"name":"Italian NRRP","award":["B53C22001820006"],"award-info":[{"award-number":["B53C22001820006"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Clinical Bioinformatics is a knowledge framework required to interpret data of medical interest via computational methods. This area became of dramatic importance in precision oncology, fueled by cancer genomic profiling: most definitions of Molecular Tumor Boards require the presence of bioinformaticians. However, all available literature remained rather vague on what are the specific needs in terms of digital tools and expertise to tackle and interpret genomics data to assign novel targeted or biomarker-driven targeted therapies to cancer patients. To fill this gap, in this article, we present a catalog of software families and human skills required for the tumor board bioinformatician, with specific examples of real-world applications associated with each element presented.<\/jats:p>","DOI":"10.1093\/bib\/bbae447","type":"journal-article","created":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T13:50:10Z","timestamp":1726753810000},"source":"Crossref","is-referenced-by-count":4,"title":["Clinical bioinformatics desiderata for molecular tumor boards"],"prefix":"10.1093","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7756-3579","authenticated-orcid":false,"given":"Matteo","family":"Pallocca","sequence":"first","affiliation":[{"name":"Institute of Experimental Endocrinology and Oncology, National Research Council , Via Sergio Pansini, 5, 80131 Naples, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Betti","sequence":"additional","affiliation":[{"name":"Biostatistics , 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