{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T21:29:49Z","timestamp":1772832589698,"version":"3.50.1"},"reference-count":42,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,9,17]],"date-time":"2024-09-17T00:00:00Z","timestamp":1726531200000},"content-version":"vor","delay-in-days":54,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100013314","name":"111 Project","doi-asserted-by":"publisher","award":["D23006"],"award-info":[{"award-number":["D23006"]}],"id":[{"id":"10.13039\/501100013314","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62272079"],"award-info":[{"award-number":["62272079"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005047","name":"Natural Science Foundation of Liaoning Province","doi-asserted-by":"publisher","award":["2022-KF-12-14"],"award-info":[{"award-number":["2022-KF-12-14"]}],"id":[{"id":"10.13039\/501100005047","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Postgraduate Education Reform Project of Liaoning Province","award":["LNYJG2022493"],"award-info":[{"award-number":["LNYJG2022493"]}]},{"name":"Dalian Outstanding Young Science and Technology Talent Support Program","award":["2022RJ08"],"award-info":[{"award-number":["2022RJ08"]}]},{"name":"Dalian","award":["2023JJ11CG002"],"award-info":[{"award-number":["2023JJ11CG002"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>DNA molecules as storage media are characterized by high encoding density and low energy consumption, making DNA storage a highly promising storage method. However, DNA storage has shortcomings, especially when storing multimedia data, wherein image reconstruction fails when address errors occur, resulting in complete data loss. Therefore, we propose a parity encoding and local mean iteration (PELMI) scheme to achieve robust DNA storage of images. The proposed parity encoding scheme satisfies the common biochemical constraints of DNA sequences and the undesired motif content. It addresses varying pixel weights at different positions for binary data, thus optimizing the utilization of Reed\u2013Solomon error correction. Then, through lost and erroneous sequences, data supplementation and local mean iteration are employed to enhance the robustness. The encoding results show that the undesired motif content is reduced by 23%\u201350% compared with the representative schemes, which improves the sequence stability. PELMI achieves image reconstruction under general errors (insertion, deletion, substitution) and enhances the DNA sequences quality. Especially under 1% error, compared with other advanced encoding schemes, the peak signal-to-noise ratio and the multiscale structure similarity address metric were increased by 10%\u201313% and 46.8%\u2013122%, respectively, and the mean squared error decreased by 113%\u2013127%. This demonstrates that the reconstructed images had better clarity, fidelity, and similarity in structure, texture, and detail. In summary, PELMI ensures robustness and stability of image storage in DNA and achieves relatively high-quality image reconstruction under general errors.<\/jats:p>","DOI":"10.1093\/bib\/bbae463","type":"journal-article","created":{"date-parts":[[2024,9,17]],"date-time":"2024-09-17T17:29:21Z","timestamp":1726594161000},"source":"Crossref","is-referenced-by-count":17,"title":["PELMI: Realize robust DNA image storage under general errors via parity encoding and local mean iteration"],"prefix":"10.1093","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1503-6009","authenticated-orcid":false,"given":"Ben","family":"Cao","sequence":"first","affiliation":[{"name":"School of Computer Science and Technology, Dalian University of Technology , No. 2 Linggong Road, Ganjingzi District, Dalian, Liaoning 116024, China"}]},{"given":"Kun","family":"Wang","sequence":"additional","affiliation":[{"name":"The Key Laboratory of Advanced Design and Intelligent Computing , Ministry of Education, School of Software Engineering, , No. 10 Xuefu Street, Dalian Economic-Technological Development Zone, Dalian, Liaoning 116622, China"},{"name":"Dalian University , Ministry of Education, School of Software Engineering, , No. 10 Xuefu Street, Dalian Economic-Technological Development Zone, Dalian, Liaoning 116622, China"}]},{"given":"Lei","family":"Xie","sequence":"additional","affiliation":[{"name":"The Key Laboratory of Advanced Design and Intelligent Computing , Ministry of Education, School of Software Engineering, , No. 10 Xuefu Street, Dalian Economic-Technological Development Zone, Dalian, Liaoning 116622, China"},{"name":"Dalian University , Ministry of Education, School of Software Engineering, , No. 10 Xuefu Street, Dalian Economic-Technological Development Zone, Dalian, Liaoning 116622, China"}]},{"given":"Jianxia","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Intelligent Engineering, Henan Institute of Technology , No. 90, East Hualan Avenue, Hongqi District, Xinxiang, Henan 451191, China"}]},{"given":"Yunzhu","family":"Zhao","sequence":"additional","affiliation":[{"name":"The Key Laboratory of Advanced Design and Intelligent Computing , Ministry of Education, School of Software Engineering, , No. 10 Xuefu Street, Dalian Economic-Technological Development Zone, Dalian, Liaoning 116622, China"},{"name":"Dalian University , Ministry of Education, School of Software Engineering, , No. 10 Xuefu Street, Dalian Economic-Technological Development Zone, Dalian, Liaoning 116622, China"}]},{"given":"Bin","family":"Wang","sequence":"additional","affiliation":[{"name":"The Key Laboratory of Advanced Design and Intelligent Computing , Ministry of Education, School of Software Engineering, , No. 10 Xuefu Street, Dalian Economic-Technological Development Zone, Dalian, Liaoning 116622, China"},{"name":"Dalian University , Ministry of Education, School of Software Engineering, , No. 10 Xuefu Street, Dalian Economic-Technological Development Zone, Dalian, Liaoning 116622, China"}]},{"given":"Pan","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Accounting and Information Systems, University of Canterbury , Upper Riccarton, Christchurch 8140, New Zealand"}]}],"member":"286","published-online":{"date-parts":[[2024,9,17]]},"reference":[{"key":"2024091717290471100_ref1","first-page":"323","article-title":"Research progress on DNA molecules for digital information storage","volume":"2","author":"Dong","year":"2021","journal-title":"Synth Biol J"},{"key":"2024091717290471100_ref2","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1038\/nbt.4079","article-title":"Random access in large-scale DNA data storage","volume":"36","author":"Organick","year":"2018","journal-title":"Nat Biotechnol"},{"key":"2024091717290471100_ref3","doi-asserted-by":"publisher","first-page":"6714","DOI":"10.1126\/sciadv.abi6714","article-title":"Scaling DNA data storage with nanoscale electrode 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