{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T08:00:56Z","timestamp":1768032056434,"version":"3.49.0"},"reference-count":97,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Briefings in Bioinformatics"],"published-print":{"date-parts":[[2010,1,1]]},"DOI":"10.1093\/bib\/bbp054","type":"journal-article","created":{"date-parts":[[2009,11,11]],"date-time":"2009-11-11T21:50:44Z","timestamp":1257976244000},"page":"80-95","source":"Crossref","is-referenced-by-count":35,"title":["The challenges of informatics in synthetic biology: from biomolecular networks to artificial organisms"],"prefix":"10.1093","volume":"11","author":[{"given":"G.","family":"Alterovitz","sequence":"first","affiliation":[]},{"given":"T.","family":"Muso","sequence":"additional","affiliation":[]},{"given":"M. F.","family":"Ramoni","sequence":"additional","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2009,11,11]]},"reference":[{"issue":"5","key":"1_22458644","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1016\/j.copbio.2006.08.001","volume":"17","author":"Huh","year":"2006","journal-title":"Current Opinion in Biotechnology","ISSN":"https:\/\/id.crossref.org\/issn\/1879-0429","issn-type":"print"},{"issue":"6","key":"2_32594366","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1016\/j.copbio.2008.10.014","volume":"19","author":"Lee","year":"2008","journal-title":"Current Opinion in Biotechnology","ISSN":"https:\/\/id.crossref.org\/issn\/1879-0429","issn-type":"print"},{"issue":"12","key":"3_22996726","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1038\/nchembio836","volume":"2","author":"Chang","year":"2006","ISSN":"https:\/\/id.crossref.org\/issn\/1552-4450","issn-type":"print"},{"issue":"29","key":"4_31449841","doi-asserted-by":"publisher","first-page":"9994","DOI":"10.1073\/pnas.0800663105","volume":"105","year":"2008","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"12","key":"5_34177268","doi-asserted-by":"publisher","first-page":"4629","DOI":"10.1073\/pnas.0800442106","volume":"106","year":"2009","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"15","key":"6_28995118","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1098\/rsif.2006.0206","volume":"4","author":"Marguet","year":"2007","journal-title":"Journal of The Royal Society Interface","ISSN":"https:\/\/id.crossref.org\/issn\/1742-5689","issn-type":"print"},{"key":"7_35966252","first-page":"1","volume":"1","year":"2003","journal-title":"MIT SYNTH BIOL WKG GRP"},{"key":"8_35966253","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1049\/iet-stb:20079020","volume":"1","year":"2007","journal-title":"IET SYNTH BIOL"},{"issue":"6","key":"9_34914274","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1038\/nrm2698","volume":"10","author":"Purnick","year":"2009","journal-title":"Nature reviews. Molecular cell biology","ISSN":"https:\/\/id.crossref.org\/issn\/1471-0072","issn-type":"print"},{"issue":"5","key":"11_34678049","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1038\/nbt.1536","volume":"27","author":"Ellis","year":"2009","journal-title":"Nature biotechnology","ISSN":"https:\/\/id.crossref.org\/issn\/1087-0156","issn-type":"print"},{"issue":"7","key":"12_31457545","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1038\/nbt1413","volume":"26","author":"Canton","year":"2008","journal-title":"Nature biotechnology","ISSN":"https:\/\/id.crossref.org\/issn\/1087-0156","issn-type":"print"},{"issue":"7","key":"13_31545395","doi-asserted-by":"publisher","first-page":"e2671","DOI":"10.1371\/journal.pone.0002671","volume":"3","author":"Peccoud","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"issue":"4","key":"15_17519775","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1093\/bioinformatics\/btg015","volume":"19","author":"Hucka","year":"2003","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"Pt 6","key":"16_17928804","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1042\/bst0311472","volume":"31","author":"Finney","year":"2003","journal-title":"Biochemical Society Transactions","ISSN":"https:\/\/id.crossref.org\/issn\/1470-8752","issn-type":"print"},{"issue":"1","key":"17_22841953","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1049\/sb:20045008","volume":"1","author":"Hucka","year":"2004","ISSN":"https:\/\/id.crossref.org\/issn\/1741-2471","issn-type":"print"},{"issue":"Suppl_4","key":"18_34477901","doi-asserted-by":"publisher","first-page":"S405","DOI":"10.1098\/rsif.2009.0035.focus","volume":"6","year":"2009","journal-title":"Journal of The Royal Society Interface","ISSN":"https:\/\/id.crossref.org\/issn\/1742-5689","issn-type":"print"},{"issue":"1895","key":"19_34501751","doi-asserted-by":"publisher","first-page":"1845","DOI":"10.1098\/rsta.2008.0310","volume":"367","author":"Beard","year":"2009","journal-title":"Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences","ISSN":"https:\/\/id.crossref.org\/issn\/1364-503X","issn-type":"print"},{"issue":"2-3","key":"20_18182497","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/j.pbiomolbio.2004.01.004","volume":"85","author":"Lloyd","year":"2004","journal-title":"Progress in biophysics and molecular biology","ISSN":"https:\/\/id.crossref.org\/issn\/0079-6107","issn-type":"print"},{"issue":"12","key":"21_19744266","doi-asserted-by":"publisher","first-page":"1509","DOI":"10.1038\/nbt1156","volume":"23","author":"Nov\u00a0\u00a0re","year":"2005","journal-title":"Nature biotechnology","ISSN":"https:\/\/id.crossref.org\/issn\/1087-0156","issn-type":"print"},{"issue":"8","key":"23_35466666","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1038\/nbt.1558","volume":"27","author":"Novere","year":"2009","journal-title":"Nature biotechnology","ISSN":"https:\/\/id.crossref.org\/issn\/1087-0156","issn-type":"print"},{"key":"28_34838830","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.1186\/1471-2202-7-S1-S11","volume":"7","year":"2006","journal-title":"BMC neuroscience [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1471-2202","issn-type":"print"},{"issue":"17","key":"29_31369128","doi-asserted-by":"publisher","first-page":"1903","DOI":"10.1093\/bioinformatics\/btn330","volume":"24","year":"2008","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"6","key":"30_30380195","doi-asserted-by":"publisher","first-page":"880","DOI":"10.1093\/bioinformatics\/btn051","volume":"24","year":"2008","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"key":"31_35966255","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1098\/rsif.2005.0067","volume":"2","year":"2005","journal-title":"J R SOC INT"},{"issue":"suppl_1","key":"32_21287605","doi-asserted-by":"publisher","first-page":"D689","DOI":"10.1093\/nar\/gkj092","volume":"34","author":"Le Novere","year":"2006","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"key":"33_31817764","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1186\/1471-2105-9-356","volume":"9","author":"Erhard","year":"2008","journal-title":"BMC bioinformatics [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1471-2105","issn-type":"print"},{"issue":"5","key":"34_34660249","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1039\/b816714c","volume":"5","author":"Hower","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/1742-2051","issn-type":"print"},{"key":"35_30580396","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/msb.2008.7","volume":"4","author":"Calzone","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1744-4292","issn-type":"print"},{"key":"36_35966256","first-page":"451S","volume":"6","year":"2009","journal-title":"J R SOC INT"},{"issue":"8","key":"37_21602950","doi-asserted-by":"publisher","first-page":"1018","DOI":"10.1093\/bioinformatics\/btl047","volume":"22","year":"2006","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"18","key":"38_31594617","doi-asserted-by":"publisher","first-page":"2122","DOI":"10.1093\/bioinformatics\/btn390","volume":"24","year":"2008","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"17","key":"39_35198863","doi-asserted-by":"publisher","first-page":"2263","DOI":"10.1093\/bioinformatics\/btp391","volume":"25","year":"2009","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"key":"41_30094113","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1186\/1752-0509-1-58","volume":"1","author":"Laibe","year":"2007","ISSN":"https:\/\/id.crossref.org\/issn\/1752-0509","issn-type":"print"},{"key":"42_31009649","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1186\/1752-0509-2-39","volume":"2","author":"Draeger","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1752-0509","issn-type":"print"},{"issue":"13","key":"43_21478646","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1016\/S1359-6446(05)03501-4","volume":"10","author":"Luciano","year":"2005","journal-title":"Drug discovery today","ISSN":"https:\/\/id.crossref.org\/issn\/1359-6446","issn-type":"print"},{"issue":"24","key":"44_21068212","doi-asserted-by":"publisher","first-page":"4401","DOI":"10.1093\/bioinformatics\/bti718","volume":"21","year":"2005","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"Suppl_4","key":"45_34595424","doi-asserted-by":"publisher","first-page":"S437","DOI":"10.1098\/rsif.2008.0516.focus","volume":"6","year":"2009","journal-title":"Journal of The Royal Society Interface","ISSN":"https:\/\/id.crossref.org\/issn\/1742-5689","issn-type":"print"},{"issue":"21","key":"47_31798069","doi-asserted-by":"publisher","first-page":"2551","DOI":"10.1093\/bioinformatics\/btn468","volume":"24","year":"2008","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"suppl_2","key":"48_34792919","doi-asserted-by":"publisher","first-page":"W40","DOI":"10.1093\/nar\/gkp361","volume":"37","year":"2009","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"key":"49_35966257","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1098\/rsta.2008.0289","volume":"367","year":"2009","journal-title":"PHILOS T ROY SOC A MATH PHYS ENG SCI"},{"key":"50_32477853","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.1038\/nprot.2007.324","volume":"2","year":"2007","journal-title":"NAT PROTOCOLS"},{"key":"51_34937334","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1186\/1471-2164-10-244","volume":"10","author":"Guziolowski","year":"2009","journal-title":"BMC genomics [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1471-2164","issn-type":"print"},{"issue":"8","key":"52_34118635","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1093\/bioinformatics\/btp101","volume":"25","year":"2009","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"19","key":"53_35369164","doi-asserted-by":"publisher","first-page":"2617","DOI":"10.1093\/bioinformatics\/btp464","volume":"25","year":"2009","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"1","key":"54_32001633","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1093\/bioinformatics\/btn501","volume":"25","year":"2009","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"key":"55_25200337","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S1478-5382(03)02370-9","volume":"1","year":"2003","journal-title":"BIOSILICO"},{"key":"56_31718004","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1186\/1472-6750-8-63","volume":"8","author":"Minaeva","year":"2008","journal-title":"BMC biotechnology [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1472-6750","issn-type":"print"},{"key":"57_34149976","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/1752-0509-3-27","volume":"3","author":"Loewe","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/1752-0509","issn-type":"print"},{"issue":"14","key":"58_34821289","doi-asserted-by":"publisher","first-page":"1822","DOI":"10.1093\/bioinformatics\/btp310","volume":"25","year":"2009","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"key":"59_35966258","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1186\/1752-0509-3-66","volume":"3","year":"2009","journal-title":"BMC SYSTEMS BIOLOGY"},{"key":"60_31221855","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1186\/1752-0509-2-47","volume":"2","author":"Banga","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1752-0509","issn-type":"print"},{"key":"61_35966259","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.ymben.2008.10.002","volume":"11","year":"2009","journal-title":"METAB ENGINEERING"},{"key":"62_35966260","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/1752-0509-2-24","volume":"2","year":"2008","journal-title":"BMC SYSTEMS BIOLOGY"},{"issue":"1","key":"63_34485670","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1016\/j.cell.2009.01.055","volume":"137","author":"Cantone","year":"2009","journal-title":"Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"},{"issue":"12","key":"64_19688895","doi-asserted-by":"publisher","first-page":"4221","DOI":"10.1073\/pnas.0501179102","volume":"102","year":"2005","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"key":"65_33560407","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/1752-0509-3-9","volume":"3","author":"Lenaerts","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/1752-0509","issn-type":"print"},{"key":"66_32158254","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1186\/1472-6807-8-43","volume":"8","author":"Lenaerts","year":"2008","journal-title":"BMC structural biology [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1472-6807","issn-type":"print"},{"issue":"4","key":"67_29024262","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/j.jbiotec.2007.05.014","volume":"130","author":"Greber","year":"2007","journal-title":"Journal of Biotechnology","ISSN":"https:\/\/id.crossref.org\/issn\/1873-4863","issn-type":"print"},{"key":"68_31054992","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/msb.2008.26","volume":"4","author":"Linshiz","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1744-4292","issn-type":"print"},{"issue":"5867","key":"69_30318489","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1126\/science.1151721","volume":"319","year":"2008","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"12","key":"70_32505022","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1016\/j.tibtech.2008.08.003","volume":"26","author":"Leonard","year":"2008","journal-title":"Trends in biotechnology","ISSN":"https:\/\/id.crossref.org\/issn\/0167-7799","issn-type":"print"},{"issue":"3","key":"71_34440980","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/j.chembiol.2009.01.010","volume":"16","author":"Martin","year":"2009","journal-title":"Chemistry & biology","ISSN":"https:\/\/id.crossref.org\/issn\/1074-5521","issn-type":"print"},{"issue":"6","key":"72_32549890","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1016\/j.mib.2008.10.002","volume":"11","author":"Lucks","year":"2008","journal-title":"Current opinion in microbiology","ISSN":"https:\/\/id.crossref.org\/issn\/1369-5274","issn-type":"print"},{"issue":"Suppl_4","key":"73_34223635","doi-asserted-by":"publisher","first-page":"S467","DOI":"10.1098\/rsif.2008.0520.focus","volume":"6","year":"2009","journal-title":"Journal of The Royal Society Interface","ISSN":"https:\/\/id.crossref.org\/issn\/1742-5689","issn-type":"print"},{"issue":"Suppl_4","key":"74_34223642","doi-asserted-by":"publisher","first-page":"S477","DOI":"10.1098\/rsif.2008.0508.focus","volume":"6","year":"2009","journal-title":"Journal of The Royal Society Interface","ISSN":"https:\/\/id.crossref.org\/issn\/1742-5689","issn-type":"print"},{"issue":"5931","key":"75_34930537","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.1126\/science.1172005","volume":"324","author":"Friedland","year":"2009","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"7227","key":"76_33544148","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1038\/nature07616","volume":"457","author":"Tigges","year":"2009","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"key":"77_35966261","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1002\/cbic.200700478","volume":"9","year":"2008","journal-title":"CHEM BIO CHEM"},{"issue":"7221","key":"78_32462174","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1038\/nature07389","volume":"456","author":"Stricker","year":"2008","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"7","key":"79_31625612","doi-asserted-by":"publisher","first-page":"e2815","DOI":"10.1371\/journal.pone.0002815","volume":"3","author":"Ham","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"issue":"5885","key":"80_31414396","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1126\/science.1156951","volume":"321","author":"Tsai","year":"2008","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"key":"81_35966262","doi-asserted-by":"crossref","first-page":"025007","DOI":"10.1088\/1478-3975\/6\/2\/025007","volume":"6","year":"2009","journal-title":"PHYSICAL BIOLOGY"},{"key":"82_22224276","doi-asserted-by":"crossref","first-page":"2006.0028","DOI":"10.1038\/msb4100073","volume":"2","author":"Andrianantoandro","year":"2006","ISSN":"https:\/\/id.crossref.org\/issn\/1744-4292","issn-type":"print"},{"issue":"5","key":"83_33843358","doi-asserted-by":"publisher","first-page":"e38","DOI":"10.1093\/nar\/gkp022","volume":"37","year":"2009","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"issue":"5","key":"84_31058253","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1038\/nbt0508-526","volume":"26","author":"Guye","year":"2008","journal-title":"Nature biotechnology","ISSN":"https:\/\/id.crossref.org\/issn\/1087-0156","issn-type":"print"},{"issue":"5869","key":"85_30612833","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1126\/science.1151153","volume":"319","author":"Bashor","year":"2008","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"5618","key":"86_17591111","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1126\/science.1083653","volume":"300","author":"Pawson","year":"2003","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"7","key":"87_35207902","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1039\/b902070p","volume":"5","author":"Weber","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/1742-2051","issn-type":"print"},{"issue":"7176","key":"88_30306680","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1038\/nature06451","volume":"451","author":"Yin","year":"2008","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"key":"89_35966263","doi-asserted-by":"crossref","first-page":"036006","DOI":"10.1088\/1478-3975\/5\/3\/036006","volume":"5","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1478-3967","issn-type":"print"},{"issue":"1","key":"90_23071044","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1101\/gr.5776007","volume":"17","year":"2007","journal-title":"Genome Research","ISSN":"https:\/\/id.crossref.org\/issn\/1088-9051","issn-type":"print"},{"key":"91_35966264","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/nmeth1143","volume":"5","year":"2008","journal-title":"NAT METH"},{"issue":"18","key":"92_22559451","doi-asserted-by":"publisher","first-page":"4133","DOI":"10.1111\/j.1742-4658.2006.05431.x","volume":"273","author":"Shimizu","year":"2006","journal-title":"FEBS Journal","ISSN":"https:\/\/id.crossref.org\/issn\/0014-2956","issn-type":"print"},{"issue":"2","key":"93_32875062","doi-asserted-by":"publisher","first-page":"e16","DOI":"10.1093\/nar\/gkn991","volume":"37","year":"2009","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"issue":"2","key":"94_32375648","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/j.abb.2008.10.009","volume":"483","author":"Fraser","year":"2009","journal-title":"Archives of Biochemistry and Biophysics","ISSN":"https:\/\/id.crossref.org\/issn\/1096-0384","issn-type":"print"},{"issue":"suppl_1","key":"95_32423556","doi-asserted-by":"publisher","first-page":"D464","DOI":"10.1093\/nar\/gkn751","volume":"37","year":"2009","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"key":"96_22532322","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/msb4100090","volume":"2","author":"Forster","year":"2006","ISSN":"https:\/\/id.crossref.org\/issn\/1744-4292","issn-type":"print"},{"issue":"1","key":"97_32869150","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1111\/j.1574-6976.2008.00151.x","volume":"33","author":"Moya","year":"2009","journal-title":"FEMS microbiology reviews","ISSN":"https:\/\/id.crossref.org\/issn\/0168-6445","issn-type":"print"},{"issue":"3","key":"98_19506533","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1038\/nchembio719","volume":"1","author":"Eloy","year":"2005","ISSN":"https:\/\/id.crossref.org\/issn\/1552-4450","issn-type":"print"},{"issue":"Pt 2","key":"99_21811505","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1042\/BST20060328","volume":"34","author":"Rackham","year":"2006","journal-title":"Biochemical Society Transactions","ISSN":"https:\/\/id.crossref.org\/issn\/1470-8752","issn-type":"print"},{"issue":"21","key":"100_34853078","doi-asserted-by":"publisher","first-page":"8477","DOI":"10.1073\/pnas.0900267106","volume":"106","year":"2009","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"1","key":"101_33416975","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1021\/cb700185e","volume":"3","author":"Filipovska","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1554-8937","issn-type":"print"},{"key":"102_35966265","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.bbamem.2008.10.017","volume":"1788","year":"2009","journal-title":"BIOCHIMICA ET BIOPHYSICA ACTA BBA BIOMEMBRANES"},{"key":"103_32218256","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1038\/msb.2008.57","volume":"4","author":"Jewett","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1744-4292","issn-type":"print"},{"issue":"5659","key":"104_18031404","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1126\/science.1091317","volume":"303","author":"Tong","year":"2004","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"1","key":"105_17980976","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1038\/nbt924","volume":"22","author":"Bader","year":"2004","journal-title":"Nature biotechnology","ISSN":"https:\/\/id.crossref.org\/issn\/1087-0156","issn-type":"print"},{"issue":"1","key":"106_17980953","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1038\/nbt921","volume":"22","author":"Lappe","year":"2004","journal-title":"Nature biotechnology","ISSN":"https:\/\/id.crossref.org\/issn\/1087-0156","issn-type":"print"}],"container-title":["Briefings in Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/bib\/article-pdf\/11\/1\/80\/484444\/bbp054.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,24]],"date-time":"2019-02-24T09:16:00Z","timestamp":1550999760000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bib\/article-lookup\/doi\/10.1093\/bib\/bbp054"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11,11]]},"references-count":97,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2010,1,22]]},"published-print":{"date-parts":[[2010,1,1]]}},"URL":"https:\/\/doi.org\/10.1093\/bib\/bbp054","relation":{},"ISSN":["1467-5463","1477-4054"],"issn-type":[{"value":"1467-5463","type":"print"},{"value":"1477-4054","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,11,11]]}}}