{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T20:43:35Z","timestamp":1760820215187},"reference-count":61,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Briefings in Bioinformatics"],"published-print":{"date-parts":[[2011,3,1]]},"DOI":"10.1093\/bib\/bbp068","type":"journal-article","created":{"date-parts":[[2010,1,8]],"date-time":"2010-01-08T03:36:02Z","timestamp":1262921762000},"page":"132-150","source":"Crossref","is-referenced-by-count":9,"title":["Comparative study of computational methods to detect the correlated reaction sets in biochemical networks"],"prefix":"10.1093","volume":"12","author":[{"given":"Y.","family":"Xi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.-P. P.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Qian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2010,1,7]]},"reference":[{"issue":"2","key":"1_18687078","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1038\/nrm1570","volume":"6","author":"Papin","year":"2005","journal-title":"Nature reviews. Molecular cell biology","ISSN":"http:\/\/id.crossref.org\/issn\/1471-0072","issn-type":"print"},{"issue":"5","key":"2_22155493","doi-asserted-by":"publisher","first-page":"e52","DOI":"10.1371\/journal.pcbi.0020052","volume":"2","author":"Barrett","year":"2006","ISSN":"http:\/\/id.crossref.org\/issn\/1553-734X","issn-type":"print"},{"issue":"2","key":"3_21461210","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1038\/nrg1769","volume":"7","author":"Reed","year":"2006","journal-title":"Nature reviews. Genetics","ISSN":"http:\/\/id.crossref.org\/issn\/1471-0056","issn-type":"print"},{"key":"4_30545442","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/1752-0509-2-20","volume":"2","author":"Goelzer","year":"2008","ISSN":"http:\/\/id.crossref.org\/issn\/1752-0509","issn-type":"print"},{"key":"5_36315937","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1038\/nrmicro1949","volume":"7","year":"2009","journal-title":"NAT REV MICRO"},{"issue":"12","key":"6_18523713","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1016\/j.tibs.2004.10.001","volume":"29","author":"Papin","year":"2004","journal-title":"Trends in biochemical sciences","ISSN":"http:\/\/id.crossref.org\/issn\/0167-7640","issn-type":"print"},{"issue":"9","key":"7_29257576","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1039\/b705597h","volume":"3","author":"Mo","year":"2007","ISSN":"http:\/\/id.crossref.org\/issn\/1742-2051","issn-type":"print"},{"issue":"2","key":"8_18028493","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1101\/gr.1926504","volume":"14","year":"2004","journal-title":"Genome Research","ISSN":"http:\/\/id.crossref.org\/issn\/1088-9051","issn-type":"print"},{"issue":"2","key":"9_21714091","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1093\/bib\/bbl007","volume":"7","year":"2006","journal-title":"Briefings in Bioinformatics","ISSN":"http:\/\/id.crossref.org\/issn\/1467-5463","issn-type":"print"},{"key":"11_25454987","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s004490100253","volume":"24","year":"2002","journal-title":"Bioprocess and biosystems engineering","ISSN":"http:\/\/id.crossref.org\/issn\/1615-7591","issn-type":"print"},{"issue":"12","key":"12_17360414","doi-asserted-by":"publisher","first-page":"1889","DOI":"10.1101\/gr.327702","volume":"12","author":"Papin","year":"2002","journal-title":"Genome Research","ISSN":"http:\/\/id.crossref.org\/issn\/1088-9051","issn-type":"print"},{"issue":"3","key":"13_10803540","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1093\/bioinformatics\/15.3.251","volume":"15","author":"Pfeiffer","year":"1999","journal-title":"Bioinformatics","ISSN":"http:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"4","key":"14_10652737","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1002\/1097-0290(2000)71:4<286::AID-BIT1018>3.0.CO;2-R","volume":"71","author":"Schilling","year":"2000","journal-title":"Biotechnology and Bioengineering","ISSN":"http:\/\/id.crossref.org\/issn\/1097-0290","issn-type":"print"},{"issue":"4","key":"15_18210057","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1016\/j.jtbi.2004.02.006","volume":"228","author":"Wiback","year":"2004","journal-title":"Journal of Theoretical Biology","ISSN":"http:\/\/id.crossref.org\/issn\/1095-8541","issn-type":"print"},{"issue":"4","key":"16_18451834","doi-asserted-by":"publisher","first-page":"2172","DOI":"10.1529\/biophysj.104.043000","volume":"87","author":"Price","year":"2004","journal-title":"Biophysical Journal","ISSN":"http:\/\/id.crossref.org\/issn\/0006-3495","issn-type":"print"},{"issue":"15","key":"17_22189105","doi-asserted-by":"publisher","first-page":"1930","DOI":"10.1093\/bioinformatics\/btl267","volume":"22","year":"2006","journal-title":"Bioinformatics","ISSN":"http:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"key":"18_28847435","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/1752-0509-1-26","volume":"1","author":"Jamshidi","year":"2007","ISSN":"http:\/\/id.crossref.org\/issn\/1752-0509","issn-type":"print"},{"issue":"9","key":"19_18306823","doi-asserted-by":"publisher","first-page":"1797","DOI":"10.1101\/gr.2546004","volume":"14","author":"Reed","year":"2004","journal-title":"Genome Research","ISSN":"http:\/\/id.crossref.org\/issn\/1088-9051","issn-type":"print"},{"issue":"12","key":"20_19711436","doi-asserted-by":"publisher","first-page":"1372","DOI":"10.1038\/ng1686","volume":"37","author":"P\u00a0\u00a0l","year":"2005","journal-title":"Nature genetics","ISSN":"http:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"1","key":"21_30354109","doi-asserted-by":"publisher","first-page":"e26","DOI":"10.1371\/journal.pcbi.0040026","volume":"4","author":"Notebaart","year":"2008","ISSN":"http:\/\/id.crossref.org\/issn\/1553-734X","issn-type":"print"},{"issue":"6","key":"22_23584928","doi-asserted-by":"publisher","first-page":"1777","DOI":"10.1073\/pnas.0610772104","volume":"104","year":"2007","journal-title":"PNAS","ISSN":"http:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"key":"23_22360125","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/msb4100077","volume":"2","author":"Jamshidi","year":"2006","ISSN":"http:\/\/id.crossref.org\/issn\/1744-4292","issn-type":"print"},{"issue":"3","key":"24_6494553","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1038\/73786","volume":"18","author":"Schuster","year":"2000","journal-title":"Nature biotechnology","ISSN":"http:\/\/id.crossref.org\/issn\/1087-0156","issn-type":"print"},{"issue":"2","key":"25_10759552","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/S0167-7799(98)01290-6","volume":"17","author":"Schuster","year":"1999","journal-title":"Trends in biotechnology","ISSN":"http:\/\/id.crossref.org\/issn\/0167-7799","issn-type":"print"},{"key":"26_28393952","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1142\/S0218339094000131","volume":"2","year":"1994","journal-title":"J BIOL SYST"},{"issue":"2","key":"27_17495363","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/S0167-7799(02)00034-3","volume":"21","author":"Klamt","year":"2003","journal-title":"Trends in biotechnology","ISSN":"http:\/\/id.crossref.org\/issn\/0167-7799","issn-type":"print"},{"issue":"3","key":"28_6512165","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1006\/jtbi.2000.1073","volume":"203","author":"Schilling","year":"2000","journal-title":"Journal of Theoretical Biology","ISSN":"http:\/\/id.crossref.org\/issn\/1095-8541","issn-type":"print"},{"issue":"8","key":"29_5963116","doi-asserted-by":"publisher","first-page":"4193","DOI":"10.1073\/pnas.95.8.4193","volume":"95","author":"Schilling","year":"1998","journal-title":"PNAS","ISSN":"http:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"8","key":"30_18400946","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1016\/j.tibtech.2004.06.010","volume":"22","author":"Papin","year":"2004","journal-title":"Trends in biotechnology","ISSN":"http:\/\/id.crossref.org\/issn\/0167-7799","issn-type":"print"},{"issue":"2","key":"31_18062988","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/j.jtbi.2003.11.016","volume":"227","author":"Papin","year":"2004","journal-title":"Journal of Theoretical Biology","ISSN":"http:\/\/id.crossref.org\/issn\/1095-8541","issn-type":"print"},{"issue":"3","key":"32_17543377","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1006\/jtbi.2003.3071","volume":"221","author":"Covert","year":"2003","journal-title":"Journal of Theoretical Biology","ISSN":"http:\/\/id.crossref.org\/issn\/1095-8541","issn-type":"print"},{"issue":"1","key":"33_30532602","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1263\/jbb.105.1","volume":"105","author":"Llaneras","year":"2008","ISSN":"http:\/\/id.crossref.org\/issn\/1347-4421","issn-type":"print"},{"issue":"5","key":"34_17643978","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1016\/S0968-0004(03)00064-1","volume":"28","author":"Papin","year":"2003","journal-title":"Trends in biochemical sciences","ISSN":"http:\/\/id.crossref.org\/issn\/0167-7640","issn-type":"print"},{"issue":"8","key":"36_18790501","doi-asserted-by":"publisher","first-page":"1739","DOI":"10.1093\/bioinformatics\/bti228","volume":"21","year":"2005","journal-title":"Bioinformatics","ISSN":"http:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"2","key":"37_17151973","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1016\/S0006-3495(02)75210-7","volume":"83","author":"Wiback","year":"2002","journal-title":"Biophysical Journal","ISSN":"http:\/\/id.crossref.org\/issn\/0006-3495","issn-type":"print"},{"issue":"5","key":"38_20041904","doi-asserted-by":"publisher","first-page":"760","DOI":"10.1101\/gr.218002. Article published online before print in April 2002","volume":"12","year":"2002","journal-title":"Genome Research","ISSN":"http:\/\/id.crossref.org\/issn\/1088-9051","issn-type":"print"},{"issue":"1","key":"39_18384513","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1529\/biophysj.103.029884","volume":"87","author":"Papin","year":"2004","journal-title":"Biophysical Journal","ISSN":"http:\/\/id.crossref.org\/issn\/0006-3495","issn-type":"print"},{"issue":"2","key":"40_30443457","doi-asserted-by":"publisher","first-page":"e36","DOI":"10.1371\/journal.pcbi.0040036","volume":"4","author":"Segura","year":"2008","ISSN":"http:\/\/id.crossref.org\/issn\/1553-734X","issn-type":"print"},{"issue":"8","key":"41_22474230","doi-asserted-by":"publisher","first-page":"e101","DOI":"10.1371\/journal.pcbi.0020101","volume":"2","author":"Gianchandani","year":"2006","ISSN":"http:\/\/id.crossref.org\/issn\/1553-734X","issn-type":"print"},{"issue":"9","key":"42_32287468","doi-asserted-by":"publisher","first-page":"5457","DOI":"10.1074\/jbc.R800048200","volume":"284","year":"2009","journal-title":"Journal of Biological Chemistry","ISSN":"http:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"key":"43_35825117","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1038\/nprot.2007.99","volume":"2","year":"2007","journal-title":"NAT PROTOCOL"},{"issue":"12","key":"44_19573442","doi-asserted-by":"publisher","first-page":"11683","DOI":"10.1074\/jbc.M409072200","volume":"280","year":"2005","journal-title":"Journal of Biological Chemistry","ISSN":"http:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"key":"45_36315938","doi-asserted-by":"crossref","first-page":"S58","DOI":"10.1186\/1471-2105-10-S1-S58","volume":"10","year":"2009","journal-title":"BMC bioinformatics [electronic resource]","ISSN":"http:\/\/id.crossref.org\/issn\/1471-2105","issn-type":"print"},{"key":"46_34243906","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/1752-0509-3-30","volume":"3","author":"Barrett","year":"2009","ISSN":"http:\/\/id.crossref.org\/issn\/1752-0509","issn-type":"print"},{"key":"47_19533902","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1186\/1471-2105-6-308","volume":"6","author":"Mackay","year":"2005","journal-title":"BMC bioinformatics [electronic resource]","ISSN":"http:\/\/id.crossref.org\/issn\/1471-2105","issn-type":"print"},{"issue":"9","key":"49_17588985","doi-asserted-by":"publisher","first-page":"2692","DOI":"10.1128\/JB.185.9.2692-2699.2003","volume":"185","author":"Reed","year":"2003","journal-title":"Journal of Bacteriology","ISSN":"http:\/\/id.crossref.org\/issn\/0021-9193","issn-type":"print"},{"issue":"11","key":"50_18480134","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1038\/nrmicro1023","volume":"2","author":"Price","year":"2004","journal-title":"Nature reviews. Microbiology","ISSN":"http:\/\/id.crossref.org\/issn\/1740-1526","issn-type":"print"},{"key":"51_24719381","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1039\/FT9918702561","volume":"87","year":"1991","journal-title":"J CHEM SOC FARADAY TRANS"},{"issue":"7","key":"52_18755667","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1093\/bioinformatics\/bti127","volume":"21","year":"2005","journal-title":"Bioinformatics","ISSN":"http:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"3","key":"53_17785953","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/S0022-5193(03)00168-1","volume":"224","author":"Wiback","year":"2003","journal-title":"Journal of Theoretical Biology","ISSN":"http:\/\/id.crossref.org\/issn\/1095-8541","issn-type":"print"},{"issue":"2","key":"54_17479811","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1016\/S0006-3495(03)74899-1","volume":"84","author":"Price","year":"2003","journal-title":"Biophysical Journal","ISSN":"http:\/\/id.crossref.org\/issn\/0006-3495","issn-type":"print"},{"issue":"3","key":"55_18356059","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1002\/bit.20011","volume":"86","author":"Wiback","year":"2004","journal-title":"Biotechnology and Bioengineering","ISSN":"http:\/\/id.crossref.org\/issn\/1097-0290","issn-type":"print"},{"issue":"2","key":"56_28479954","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1016\/j.jtbi.2006.12.029","volume":"246","author":"Llaneras","year":"2007","journal-title":"Journal of Theoretical Biology","ISSN":"http:\/\/id.crossref.org\/issn\/1095-8541","issn-type":"print"},{"issue":"1-2","key":"57_17246897","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1023\/A:1020390132244","volume":"29","author":"Klamt","year":"2002","journal-title":"Molecular biology reports","ISSN":"http:\/\/id.crossref.org\/issn\/0301-4851","issn-type":"print"},{"issue":"1","key":"58_29522050","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1186\/1471-2105-8-363","volume":"8","author":"Yeung","year":"2007","journal-title":"BMC bioinformatics [electronic resource]","ISSN":"http:\/\/id.crossref.org\/issn\/1471-2105","issn-type":"print"},{"issue":"1","key":"59_25760729","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1287\/opre.46.1.84","volume":"46","author":"Kaufman","year":"1998","journal-title":"Operations Research","ISSN":"http:\/\/id.crossref.org\/issn\/0030-364X","issn-type":"print"},{"issue":"9","key":"60_17795127","doi-asserted-by":"publisher","first-page":"R54","DOI":"10.1186\/gb-2003-4-9-r54","volume":"4","author":"Reed","year":"2003","journal-title":"Genome biology","ISSN":"http:\/\/id.crossref.org\/issn\/1465-6906","issn-type":"print"},{"issue":"7","key":"61_18246612","doi-asserted-by":"publisher","first-page":"1298","DOI":"10.1101\/gr.2250904","volume":"14","year":"2004","journal-title":"Genome Research","ISSN":"http:\/\/id.crossref.org\/issn\/1088-9051","issn-type":"print"},{"key":"62_36315939","first-page":"1093","volume":"244","year":"1979","journal-title":"DOKLADY AKADCMLZ NAUK SSSR"},{"key":"63_24245809","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1007\/BF02579150","volume":"4","year":"1984","journal-title":"COMBINATORICA"},{"key":"64_36315940","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/BF01580724","volume":"40","year":"1988","journal-title":"MATH PROGRAM"}],"container-title":["Briefings in Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/bib\/article-pdf\/12\/2\/132\/723619\/bbp068.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,25]],"date-time":"2019-05-25T01:06:22Z","timestamp":1558746382000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bib\/article-lookup\/doi\/10.1093\/bib\/bbp068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1,7]]},"references-count":61,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2011,3,21]]},"published-print":{"date-parts":[[2011,3,1]]}},"URL":"https:\/\/doi.org\/10.1093\/bib\/bbp068","relation":{},"ISSN":["1467-5463","1477-4054"],"issn-type":[{"value":"1467-5463","type":"print"},{"value":"1477-4054","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,1,7]]}}}