{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T12:42:39Z","timestamp":1767962559581,"version":"3.49.0"},"reference-count":106,"publisher":"Oxford University Press (OUP)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Briefings in Bioinformatics"],"published-print":{"date-parts":[[2011,7,1]]},"DOI":"10.1093\/bib\/bbr011","type":"journal-article","created":{"date-parts":[[2011,3,27]],"date-time":"2011-03-27T00:25:52Z","timestamp":1301185552000},"page":"312-326","source":"Crossref","is-referenced-by-count":117,"title":["Old friends in new guise: repositioning of known drugs with structural bioinformatics"],"prefix":"10.1093","volume":"12","author":[{"given":"V. J.","family":"Haupt","sequence":"first","affiliation":[]},{"given":"M.","family":"Schroeder","sequence":"additional","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2011,3,26]]},"reference":[{"issue":"9208","key":"1_6553633","doi-asserted-by":"publisher","first-page":"1022","DOI":"10.1016\/S0140-6736(05)74775-9","volume":"355","author":"Raju","year":"2000","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"issue":"7154","key":"2_29214919","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1038\/448645a","volume":"448","author":"Chong","year":"2007","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"2","key":"3_17516743","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/S0167-6296(02)00126-1","volume":"22","author":"DiMasi","year":"2003","journal-title":"Journal of health economics","ISSN":"https:\/\/id.crossref.org\/issn\/0167-6296","issn-type":"print"},{"issue":"11","key":"5_22815183","doi-asserted-by":"publisher","first-page":"1295","DOI":"10.1517\/13543784.15.11.1295","volume":"15","author":"Tartaglia","year":"2006","journal-title":"Expert opinion on investigational drugs","ISSN":"https:\/\/id.crossref.org\/issn\/1354-3784","issn-type":"print"},{"issue":"23-24","key":"6_30041093","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1016\/j.drudis.2007.10.004","volume":"12","author":"Nielsch","year":"2007","journal-title":"Drug discovery today","ISSN":"https:\/\/id.crossref.org\/issn\/1359-6446","issn-type":"print"},{"issue":"5","key":"7_29675460","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1111\/j.1365-2125.2007.03058.x","volume":"64","author":"Aronson","year":"2007","journal-title":"British journal of clinical pharmacology","ISSN":"https:\/\/id.crossref.org\/issn\/0306-5251","issn-type":"print"},{"issue":"2","key":"8_34484776","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1358\/dnp.2009.22.2.1343228","volume":"22","author":"Tobinick","year":"2009","journal-title":"Drug news & perspectives","ISSN":"https:\/\/id.crossref.org\/issn\/0214-0934","issn-type":"print"},{"issue":"8","key":"9_18279014","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1038\/nrd1468","volume":"3","author":"Ashburn","year":"2004","journal-title":"Nature reviews. Drug discovery","ISSN":"https:\/\/id.crossref.org\/issn\/1474-1776","issn-type":"print"},{"issue":"12","key":"10_38540988","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1038\/nrd3275","volume":"9","author":"Tambuyzer","year":"2010","journal-title":"Nature reviews. Drug discovery","ISSN":"https:\/\/id.crossref.org\/issn\/1474-1776","issn-type":"print"},{"key":"12_36483553","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1038\/msb.2009.98","volume":"6","author":"Kuhn","year":"2010","ISSN":"https:\/\/id.crossref.org\/issn\/1744-4292","issn-type":"print"},{"key":"13_39555885","first-page":"449","volume":"3","year":"2011","journal-title":"Current pharmaceutical biotechnology","ISSN":"https:\/\/id.crossref.org\/issn\/1389-2010","issn-type":"print"},{"issue":"5","key":"14_37792292","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1007\/s12265-010-9214-6","volume":"3","author":"Dudley","year":"2010","ISSN":"https:\/\/id.crossref.org\/issn\/1937-5387","issn-type":"print"},{"issue":"15-16","key":"15_37843676","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1016\/j.drudis.2010.05.015","volume":"15","author":"Perot","year":"2010","journal-title":"Drug discovery today","ISSN":"https:\/\/id.crossref.org\/issn\/1359-6446","issn-type":"print"},{"issue":"8","key":"16_38068885","doi-asserted-by":"publisher","first-page":"e12214","DOI":"10.1371\/journal.pone.0012214","volume":"5","author":"De Franchi","year":"2010","ISSN":"https:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"issue":"3","key":"17_18006595","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1021\/jm030912m","volume":"47","author":"Weber","year":"2004","journal-title":"Journal of medicinal chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0022-2623","issn-type":"print"},{"issue":"2","key":"18_34018401","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1038\/nbt1519","volume":"27","author":"Nobeli","year":"2009","journal-title":"Nature biotechnology","ISSN":"https:\/\/id.crossref.org\/issn\/1087-0156","issn-type":"print"},{"issue":"9","key":"19_23056503","doi-asserted-by":"publisher","first-page":"e124","DOI":"10.1371\/journal.pcbi.0020124","volume":"2","author":"Kim","year":"2006","ISSN":"https:\/\/id.crossref.org\/issn\/1553-734X","issn-type":"print"},{"issue":"1","key":"20_36025099","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.jtbi.2009.11.008","volume":"263","author":"Whitacre","year":"2010","journal-title":"Journal of Theoretical Biology","ISSN":"https:\/\/id.crossref.org\/issn\/1095-8541","issn-type":"print"},{"issue":"10","key":"21_22761793","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1038\/nrd2132","volume":"5","author":"Imming","year":"2006","journal-title":"Nature reviews. Drug discovery","ISSN":"https:\/\/id.crossref.org\/issn\/1474-1776","issn-type":"print"},{"issue":"12","key":"22_23069210","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1038\/nrd2199","volume":"5","author":"Overington","year":"2006","journal-title":"Nature reviews. Drug discovery","ISSN":"https:\/\/id.crossref.org\/issn\/1474-1776","issn-type":"print"},{"issue":"suppl_1","key":"23_21287581","doi-asserted-by":"publisher","first-page":"D668","DOI":"10.1093\/nar\/gkj067","volume":"34","author":"Wishart","year":"2006","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"issue":"7","key":"24_22386080","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1038\/nbt1228","volume":"24","author":"Paolini","year":"2006","journal-title":"Nature biotechnology","ISSN":"https:\/\/id.crossref.org\/issn\/1087-0156","issn-type":"print"},{"issue":"23-24","key":"25_38391282","doi-asserted-by":"publisher","first-page":"1052","DOI":"10.1016\/j.drudis.2010.10.003","volume":"15","author":"Li","year":"2010","journal-title":"Drug discovery today","ISSN":"https:\/\/id.crossref.org\/issn\/1359-6446","issn-type":"print"},{"issue":"7061","key":"26_19466402","doi-asserted-by":"publisher","first-page":"942","DOI":"10.1038\/437942a","volume":"437","author":"Frantz","year":"2005","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"1","key":"27_18803078","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/1472-6904-5-3","volume":"5","author":"Aminian","year":"2005","journal-title":"BMC clinical pharmacology [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1472-6904","issn-type":"print"},{"issue":"1","key":"28_21625440","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.sbi.2006.01.013","volume":"16","author":"Hopkins","year":"2006","journal-title":"Current opinion in structural biology","ISSN":"https:\/\/id.crossref.org\/issn\/0959-440X","issn-type":"print"},{"issue":"11","key":"29_32314373","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1038\/nchembio.118","volume":"4","author":"Hopkins","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1552-4450","issn-type":"print"},{"issue":"7270","key":"30_35906975","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1038\/nature08506","volume":"462","author":"Keiser","year":"2009","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"key":"31_37375638","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/prot.22513","volume":"77","year":"2009","journal-title":"Proteins","ISSN":"https:\/\/id.crossref.org\/issn\/0887-3585","issn-type":"print"},{"issue":"19","key":"32_17225537","doi-asserted-by":"publisher","first-page":"4350","DOI":"10.1021\/jm020155c","volume":"45","author":"Martin","year":"2002","journal-title":"Journal of medicinal chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0022-2623","issn-type":"print"},{"issue":"1","key":"33_23521414","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1111\/j.1365-4632.2006.03079.x","volume":"46","author":"Wolf","year":"2007","journal-title":"International journal of dermatology","ISSN":"https:\/\/id.crossref.org\/issn\/0011-9059","issn-type":"print"},{"issue":"8573","key":"34_14343625","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1016\/S0140-6736(87)91131-7","volume":"2","author":"Pepin","year":"1987","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"issue":"4-5","key":"35_18513525","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/j.drup.2004.07.002","volume":"7","author":"Ouellette","year":"2004","journal-title":"Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/1368-7646","issn-type":"print"},{"issue":"3","key":"36_28919055","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1093\/jac\/dkm219","volume":"60","year":"2007","journal-title":"Journal of Antimicrobial Chemotherapy","ISSN":"https:\/\/id.crossref.org\/issn\/0305-7453","issn-type":"print"},{"issue":"8","key":"37_22481579","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1038\/nchembio806","volume":"2","author":"Chong","year":"2006","ISSN":"https:\/\/id.crossref.org\/issn\/1552-4450","issn-type":"print"},{"issue":"8","key":"38_36539799","doi-asserted-by":"publisher","first-page":"3424","DOI":"10.1073\/pnas.0915125107","volume":"107","year":"2010","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"9","key":"39_35450998","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1016\/j.tibtech.2009.06.003","volume":"27","author":"Yao","year":"2009","journal-title":"Trends in biotechnology","ISSN":"https:\/\/id.crossref.org\/issn\/0167-7799","issn-type":"print"},{"issue":"5918","key":"40_34139245","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1126\/science.1167498","volume":"323","author":"Hugonnet","year":"2009","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"1","key":"41_33402998","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/S1470-2045(08)70334-6","volume":"10","author":"Chow","year":"2009","journal-title":"The lancet oncology","ISSN":"https:\/\/id.crossref.org\/issn\/1470-2045","issn-type":"print"},{"issue":"6","key":"42_34617909","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1097\/COH.0b013e328313915d","volume":"3","author":"Bernstein","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1746-630X","issn-type":"print"},{"issue":"35","key":"43_35349178","doi-asserted-by":"publisher","first-page":"6448","DOI":"10.1002\/anie.200902981","volume":"48","author":"Lee","year":"2009","journal-title":"Angewandte Chemie (International Edition in English).","ISSN":"https:\/\/id.crossref.org\/issn\/1433-7851","issn-type":"print"},{"key":"44_39555886","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1002\/cmdc.200900384","volume":"4","year":"2009","journal-title":"CHEM MED CHEM"},{"issue":"4","key":"45_28522182","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1021\/cb600362d","volume":"2","author":"Chong","year":"2007","ISSN":"https:\/\/id.crossref.org\/issn\/1554-8937","issn-type":"print"},{"issue":"5","key":"46_39073340","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1007\/s13238-010-0063-5","volume":"1","author":"Giambelli","year":"2010","ISSN":"https:\/\/id.crossref.org\/issn\/1674-8018","issn-type":"print"},{"issue":"7","key":"47_36702921","doi-asserted-by":"publisher","first-page":"1532","DOI":"10.1111\/j.1476-5381.2010.00658.x","volume":"159","author":"de Boer","year":"2010","journal-title":"British journal of pharmacology","ISSN":"https:\/\/id.crossref.org\/issn\/0007-1188","issn-type":"print"},{"issue":"12","key":"48_19507452","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1038\/nrd1900","volume":"4","author":"Brophy","year":"2005","journal-title":"Nature reviews. Drug discovery","ISSN":"https:\/\/id.crossref.org\/issn\/1474-1776","issn-type":"print"},{"issue":"21","key":"49_6353087","doi-asserted-by":"publisher","first-page":"1565","DOI":"10.1056\/NEJM199911183412102","volume":"341","author":"Singhal","year":"1999","journal-title":"New England Journal of Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"issue":"20","key":"50_5987523","doi-asserted-by":"publisher","first-page":"1397","DOI":"10.1056\/NEJM199805143382001","volume":"338","author":"Goldstein","year":"1998","journal-title":"New England Journal of Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"issue":"suppl_1","key":"51_36018909","doi-asserted-by":"publisher","first-page":"D787","DOI":"10.1093\/nar\/gkp1014","volume":"38","year":"2010","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"issue":"suppl_1","key":"52_29934971","doi-asserted-by":"publisher","first-page":"D901","DOI":"10.1093\/nar\/gkm958","volume":"36","year":"2008","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"issue":"suppl_1","key":"53_29650078","doi-asserted-by":"publisher","first-page":"D919","DOI":"10.1093\/nar\/gkm862","volume":"36","year":"2008","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"issue":"suppl_1","key":"54_23050195","doi-asserted-by":"publisher","first-page":"D198","DOI":"10.1093\/nar\/gkl999","volume":"35","year":"2007","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"issue":"1","key":"55_6399241","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1093\/nar\/28.1.235","volume":"28","author":"Berman","year":"2000","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"issue":"suppl_1","key":"56_38417708","doi-asserted-by":"publisher","first-page":"D392","DOI":"10.1093\/nar\/gkq1021","volume":"39","year":"2011","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"issue":"2","key":"57_21844170","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1021\/ci050372x","volume":"46","author":"Kellenberger","year":"2006","journal-title":"Journal of chemical information and modeling","ISSN":"https:\/\/id.crossref.org\/issn\/1549-9596","issn-type":"print"},{"issue":"suppl_1","key":"58_38556910","doi-asserted-by":"publisher","first-page":"D411","DOI":"10.1093\/nar\/gkq1105","volume":"39","year":"2011","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"key":"59_39555887","doi-asserted-by":"crossref","first-page":"209","DOI":"10.2174\/157340908785747401","volume":"4","year":"2008","journal-title":"CURRENT COMPUTERAIDED DRUG DESIGN"},{"issue":"15","key":"60_37423471","doi-asserted-by":"publisher","first-page":"1913","DOI":"10.1093\/bioinformatics\/btq288","volume":"26","year":"2010","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"9","key":"61_36903298","doi-asserted-by":"publisher","first-page":"1160","DOI":"10.1093\/bioinformatics\/btq100","volume":"26","year":"2010","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"8","key":"62_37903754","doi-asserted-by":"publisher","first-page":"e11988","DOI":"10.1371\/journal.pone.0011988","volume":"5","author":"Gherardini","year":"2010","ISSN":"https:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"key":"63_36700647","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1186\/1471-2105-11-99","volume":"11","author":"Hoffmann","year":"2010","journal-title":"BMC bioinformatics [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1471-2105","issn-type":"print"},{"issue":"4","key":"64_31229130","doi-asserted-by":"publisher","first-page":"1755","DOI":"10.1002\/prot.21858","volume":"71","author":"Schalon","year":"2008","journal-title":"Proteins","ISSN":"https:\/\/id.crossref.org\/issn\/0887-3585","issn-type":"print"},{"issue":"suppl_2","key":"65_37314836","doi-asserted-by":"publisher","first-page":"W441","DOI":"10.1093\/nar\/gkq400","volume":"38","year":"2010","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"key":"66_33385489","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1186\/1471-2105-9-543","volume":"9","author":"Yeturu","year":"2008","journal-title":"BMC bioinformatics [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1471-2105","issn-type":"print"},{"issue":"2","key":"67_35580297","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/jmr.984","volume":"23","author":"Henrich","year":"2010","journal-title":"Journal of molecular recognition : JMR","ISSN":"https:\/\/id.crossref.org\/issn\/0952-3499","issn-type":"print"},{"issue":"1","key":"68_36487290","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1021\/ci900349y","volume":"50","author":"Weill","year":"2010","journal-title":"Journal of chemical information and modeling","ISSN":"https:\/\/id.crossref.org\/issn\/1549-9596","issn-type":"print"},{"issue":"2","key":"69_30749494","doi-asserted-by":"publisher","first-page":"960","DOI":"10.1002\/prot.21780","volume":"71","author":"Park","year":"2008","journal-title":"Proteins","ISSN":"https:\/\/id.crossref.org\/issn\/0887-3585","issn-type":"print"},{"issue":"5","key":"70_21103059","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1093\/bioinformatics\/bti782","volume":"22","year":"2006","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"2","key":"71_18233538","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1002\/prot.20123","volume":"56","author":"Brakoulias","year":"2004","journal-title":"Proteins","ISSN":"https:\/\/id.crossref.org\/issn\/0887-3585","issn-type":"print"},{"issue":"14","key":"72_30728413","doi-asserted-by":"publisher","first-page":"5441","DOI":"10.1073\/pnas.0704422105","volume":"105","year":"2008","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"1","key":"73_36488948","doi-asserted-by":"publisher","first-page":"e1000648","DOI":"10.1371\/journal.pcbi.1000648","volume":"6","author":"Durrant","year":"2010","ISSN":"https:\/\/id.crossref.org\/issn\/1553-734X","issn-type":"print"},{"key":"74_39555888","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1002\/minf.200900081","volume":"29","year":"2010","journal-title":"MOL INFORM"},{"issue":"8","key":"75_37742083","doi-asserted-by":"publisher","first-page":"1418","DOI":"10.1021\/ci1001263","volume":"50","author":"Milletti","year":"2010","journal-title":"Journal of chemical information and modeling","ISSN":"https:\/\/id.crossref.org\/issn\/1549-9596","issn-type":"print"},{"issue":"7","key":"76_35241929","doi-asserted-by":"publisher","first-page":"e1000423","DOI":"10.1371\/journal.pcbi.1000423","volume":"5","author":"Kinnings","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/1553-734X","issn-type":"print"},{"issue":"5","key":"77_34860522","doi-asserted-by":"publisher","first-page":"e1000387","DOI":"10.1371\/journal.pcbi.1000387","volume":"5","author":"Xie","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/1553-734X","issn-type":"print"},{"issue":"1","key":"78_31244897","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1002\/prot.21933","volume":"72","author":"Minai","year":"2008","journal-title":"Proteins","ISSN":"https:\/\/id.crossref.org\/issn\/0887-3585","issn-type":"print"},{"issue":"5","key":"79_21348875","doi-asserted-by":"publisher","first-page":"1112","DOI":"10.1016\/j.jmb.2005.11.044","volume":"355","author":"Gold","year":"2006","journal-title":"Journal of molecular biology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-2836","issn-type":"print"},{"issue":"suppl_1","key":"82_32275807","doi-asserted-by":"publisher","first-page":"D387","DOI":"10.1093\/nar\/gkn750","volume":"37","year":"2009","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"key":"83_39555889","doi-asserted-by":"crossref","first-page":"D465","DOI":"10.1093\/nar\/gkq1091","volume":"39","year":"2010","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"issue":"1","key":"84_32749264","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10969-008-9048-5","volume":"10","author":"Arnold","year":"2009","journal-title":"Journal of structural and functional genomics","ISSN":"https:\/\/id.crossref.org\/issn\/1345-711X","issn-type":"print"},{"issue":"2","key":"85_34485843","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/j.sbi.2009.02.005","volume":"19","author":"Zhang","year":"2009","journal-title":"Current opinion in structural biology","ISSN":"https:\/\/id.crossref.org\/issn\/0959-440X","issn-type":"print"},{"key":"86_22633937","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1186\/1472-6807-6-19","volume":"6","author":"Huang","year":"2006","journal-title":"BMC structural biology [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1472-6807","issn-type":"print"},{"issue":"1","key":"87_36333403","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1021\/ci9003943","volume":"50","author":"Rueda","year":"2010","journal-title":"Journal of chemical information and modeling","ISSN":"https:\/\/id.crossref.org\/issn\/1549-9596","issn-type":"print"},{"issue":"4","key":"88_38072331","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1002\/jcc.21643","volume":"32","author":"Plewczynski","year":"2011","journal-title":"Journal of computational chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0192-8651","issn-type":"print"},{"issue":"6","key":"89_37585678","doi-asserted-by":"publisher","first-page":"e1000821","DOI":"10.1371\/journal.pcbi.1000821","volume":"6","author":"Martin","year":"2010","ISSN":"https:\/\/id.crossref.org\/issn\/1553-734X","issn-type":"print"},{"issue":"5685","key":"90_18285518","doi-asserted-by":"publisher","first-page":"866","DOI":"10.1126\/science.1099190","volume":"305","author":"Nettles","year":"2004","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"11","key":"91_36680013","doi-asserted-by":"publisher","first-page":"3809","DOI":"10.1093\/nar\/gkq090","volume":"38","year":"2010","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"key":"92_38097433","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1007\/978-1-60761-800-3_2","volume":"662","author":"Schrattenholz","year":"2010","journal-title":"Methods in molecular biology (Clifton, N.J.)","ISSN":"https:\/\/id.crossref.org\/issn\/1064-3745","issn-type":"print"},{"issue":"1-2","key":"93_35822009","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.drudis.2009.09.011","volume":"15","author":"Campbell","year":"2010","journal-title":"Drug discovery today","ISSN":"https:\/\/id.crossref.org\/issn\/1359-6446","issn-type":"print"},{"issue":"3","key":"94_36625508","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.tips.2009.11.006","volume":"31","author":"Pujol","year":"2010","journal-title":"Trends in Pharmacological Sciences (Regular ed.)","ISSN":"https:\/\/id.crossref.org\/issn\/1873-3735","issn-type":"print"},{"key":"95_39555890","first-page":"116","volume":"7","year":"2010","ISSN":"https:\/\/id.crossref.org\/issn\/1613-4516","issn-type":"print"},{"issue":"7","key":"96_31519503","doi-asserted-by":"publisher","first-page":"e1000108","DOI":"10.1371\/journal.pcbi.1000108","volume":"4","author":"Royer","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1553-734X","issn-type":"print"},{"key":"97_39555891","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1517\/17460440903322234","volume":"4","year":"2009","journal-title":"EXPERT OPIN DRUG DIS"},{"issue":"33","key":"98_37777862","doi-asserted-by":"publisher","first-page":"14621","DOI":"10.1073\/pnas.1000138107","volume":"107","year":"2010","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"6","key":"99_32033435","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1093\/bib\/bbn035","volume":"9","year":"2008","journal-title":"Briefings in Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1467-5463","issn-type":"print"},{"issue":"4","key":"100_36967081","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1016\/j.jbi.2010.03.008","volume":"43","author":"Baker","year":"2010","journal-title":"Journal of biomedical informatics","ISSN":"https:\/\/id.crossref.org\/issn\/1532-0464","issn-type":"print"},{"issue":"12","key":"101_37396020","doi-asserted-by":"publisher","first-page":"i246","DOI":"10.1093\/bioinformatics\/btq176","volume":"26","year":"2010","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"5886","key":"102_31453211","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1126\/science.1158140","volume":"321","author":"Campillos","year":"2008","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"5","key":"103_35231912","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1038\/clpt.2009.103","volume":"86","author":"Chiang","year":"2009","journal-title":"Clinical pharmacology and therapeutics","ISSN":"https:\/\/id.crossref.org\/issn\/0009-9236","issn-type":"print"},{"issue":"2","key":"104_29049812","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1038\/sj.clpt.6100258","volume":"82","author":"Almenoff","year":"2007","journal-title":"Clinical pharmacology and therapeutics","ISSN":"https:\/\/id.crossref.org\/issn\/0009-9236","issn-type":"print"},{"issue":"3","key":"105_36797340","doi-asserted-by":"publisher","first-page":"e9568","DOI":"10.1371\/journal.pone.0009568","volume":"5","author":"Yang","year":"2010","ISSN":"https:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"issue":"30","key":"106_33373074","doi-asserted-by":"publisher","first-page":"3196","DOI":"10.2174\/092986708786848488","volume":"15","author":"Bernard","year":"2008","journal-title":"Current medicinal chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0929-8673","issn-type":"print"},{"issue":"3","key":"107_31614282","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1038\/bjp.2008.307","volume":"155","author":"Spina","year":"2008","journal-title":"British journal of pharmacology","ISSN":"https:\/\/id.crossref.org\/issn\/0007-1188","issn-type":"print"},{"issue":"4","key":"108_37029130","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1038\/nrd3139","volume":"9","author":"Schneider","year":"2010","journal-title":"Nature reviews. Drug discovery","ISSN":"https:\/\/id.crossref.org\/issn\/1474-1776","issn-type":"print"},{"issue":"suppl_2","key":"109_37185597","doi-asserted-by":"publisher","first-page":"W609","DOI":"10.1093\/nar\/gkq300","volume":"38","year":"2010","journal-title":"Nucleic Acids Research","ISSN":"https:\/\/id.crossref.org\/issn\/0305-1048","issn-type":"print"},{"issue":"3","key":"110_33559987","doi-asserted-by":"publisher","first-page":"258","DOI":"10.2174\/092986709787002655","volume":"16","author":"Schneider","year":"2009","journal-title":"Current medicinal chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0929-8673","issn-type":"print"}],"container-title":["Briefings in Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/bib\/article-pdf\/12\/4\/312\/663355\/bbr011.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T13:18:08Z","timestamp":1712323088000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bib\/article-lookup\/doi\/10.1093\/bib\/bbr011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,26]]},"references-count":106,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2011,7,17]]},"published-print":{"date-parts":[[2011,7,1]]}},"URL":"https:\/\/doi.org\/10.1093\/bib\/bbr011","relation":{},"ISSN":["1467-5463","1477-4054"],"issn-type":[{"value":"1467-5463","type":"print"},{"value":"1477-4054","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,26]]}}}