{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T23:00:15Z","timestamp":1774306815815,"version":"3.50.1"},"reference-count":157,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Briefings in Bioinformatics"],"published-print":{"date-parts":[[2012,1,1]]},"DOI":"10.1093\/bib\/bbr012","type":"journal-article","created":{"date-parts":[[2011,3,27]],"date-time":"2011-03-27T00:25:52Z","timestamp":1301185552000},"page":"1-19","source":"Crossref","is-referenced-by-count":148,"title":["Travelling the world of gene-gene interactions"],"prefix":"10.1093","volume":"13","author":[{"given":"K.","family":"Van Steen","sequence":"first","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2011,3,26]]},"reference":[{"issue":"8","key":"1_18268011","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1038\/nrg1407","volume":"5","author":"Carlborg","year":"2004","journal-title":"Nature reviews. Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1471-0056","issn-type":"print"},{"issue":"3","key":"2_21669539","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1038\/nrm1857","volume":"7","author":"Joyce","year":"2006","journal-title":"Nature reviews. Molecular cell biology","ISSN":"https:\/\/id.crossref.org\/issn\/1471-0072","issn-type":"print"},{"issue":"39","key":"3_22602906","doi-asserted-by":"publisher","first-page":"14402","DOI":"10.1073\/pnas.0604543103","volume":"103","year":"2006","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"7","key":"4_31589541","doi-asserted-by":"publisher","first-page":"e2663","DOI":"10.1371\/journal.pone.0002663","volume":"3","author":"Sanjuan","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"issue":"1","key":"5_18604337","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1038\/ng0105-13","volume":"37","author":"Moore","year":"2005","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"10","key":"6_34310289","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.1038\/ejhg.2009.15","volume":"17","author":"Emily","year":"2009","journal-title":"European journal of human genetics : EJHG","ISSN":"https:\/\/id.crossref.org\/issn\/1018-4813","issn-type":"print"},{"issue":"3","key":"7_36502373","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1002\/gepi.20459","volume":"34","author":"Wu","year":"2010","journal-title":"Genetic epidemiology","ISSN":"https:\/\/id.crossref.org\/issn\/0741-0395","issn-type":"print"},{"key":"9_24273786","first-page":"399","volume":"52","year":"1918","journal-title":"TRANS R SOC EDINB"},{"key":"10_39556137","first-page":"74","volume":"12","year":"2010","journal-title":"Nature reviews. Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1471-0056","issn-type":"print"},{"issue":"6","key":"11_34850303","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1038\/nrg2579","volume":"10","author":"Cordell","year":"2009","journal-title":"Nature reviews. Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1471-0056","issn-type":"print"},{"issue":"4","key":"12_38868060","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1159\/000321967","volume":"70","author":"Wang","year":"2010","journal-title":"Human heredity","ISSN":"https:\/\/id.crossref.org\/issn\/0001-5652","issn-type":"print"},{"issue":"11","key":"13_32208847","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1038\/nrg2452","volume":"9","author":"Phillips","year":"2008","journal-title":"Nature reviews. Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1471-0056","issn-type":"print"},{"issue":"7111","key":"14_22773493","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1038\/nature05133","volume":"443","author":"Gregersen","year":"2006","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"10","key":"15_19442144","doi-asserted-by":"publisher","first-page":"1147","DOI":"10.1038\/ng1640","volume":"37","author":"Davierwala","year":"2005","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"2","key":"16_11475402","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1086\/338759","volume":"70","author":"Culverhouse","year":"2002","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"issue":"6","key":"17_10396631","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1159\/000022939","volume":"50","author":"Li","year":"2000","journal-title":"Human heredity","ISSN":"https:\/\/id.crossref.org\/issn\/0001-5652","issn-type":"print"},{"key":"18_30502930","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/1471-2156-9-17","volume":"9","author":"Hallgrimsdottir","year":"2008","journal-title":"BMC genetics [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1471-2156","issn-type":"print"},{"key":"19_39556138","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1186\/1479-7364-2-5-336","volume":"2","year":"2006","journal-title":"HUM GENOM"},{"issue":"2","key":"20_23622170","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1159\/000099179","volume":"63","author":"Musani","year":"2007","journal-title":"Human heredity","ISSN":"https:\/\/id.crossref.org\/issn\/0001-5652","issn-type":"print"},{"key":"23_39556139","doi-asserted-by":"crossref","first-page":"S78","DOI":"10.1186\/1753-6561-3-s7-s78","volume":"3","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/1753-6561","issn-type":"print"},{"key":"24_37236241","first-page":"1157","volume":"3","year":"2003","journal-title":"J MACHINE LEARN RES"},{"issue":"19","key":"25_29282250","doi-asserted-by":"publisher","first-page":"2507","DOI":"10.1093\/bioinformatics\/btm344","volume":"23","year":"2007","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"2","key":"26_30578979","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1038\/sj.ejhg.5201921","volume":"16","author":"Dong","year":"2008","journal-title":"European journal of human genetics : EJHG","ISSN":"https:\/\/id.crossref.org\/issn\/1018-4813","issn-type":"print"},{"issue":"14","key":"27_22404490","doi-asserted-by":"publisher","first-page":"e497","DOI":"10.1093\/bioinformatics\/btl224","volume":"22","author":"Varadan","year":"2006","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"1","key":"30_35650202","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/1756-0381-2-5","volume":"2","author":"Greene","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/1756-0381","issn-type":"print"},{"issue":"16","key":"31_28925360","doi-asserted-by":"publisher","first-page":"2113","DOI":"10.1093\/bioinformatics\/btm317","volume":"23","year":"2007","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"24","key":"32_29876442","doi-asserted-by":"publisher","first-page":"3280","DOI":"10.1093\/bioinformatics\/btm522","volume":"23","year":"2007","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"key":"33_39556236","first-page":"37","volume":"5217\/2008","year":"2008","journal-title":"LECT NOTES COMPUT SCI"},{"key":"34_37200325","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1186\/1756-0500-3-117","volume":"3","author":"Wang","year":"2010","ISSN":"https:\/\/id.crossref.org\/issn\/1756-0500","issn-type":"print"},{"issue":"1","key":"35_28900228","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1093\/biostatistics\/kxm024","volume":"9","year":"2008","journal-title":"Biostatistics","ISSN":"https:\/\/id.crossref.org\/issn\/1465-4644","issn-type":"print"},{"issue":"1","key":"36_37541159","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1093\/biostatistics\/kxq042","volume":"12","year":"2011","journal-title":"Biostatistics","ISSN":"https:\/\/id.crossref.org\/issn\/1465-4644","issn-type":"print"},{"key":"37_23652825","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/msb4100124","volume":"3","author":"Anastassiou","year":"2007","ISSN":"https:\/\/id.crossref.org\/issn\/1744-4292","issn-type":"print"},{"key":"38_39214461","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1534\/genetics.108.088542","volume":"180","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1943-2631","issn-type":"print"},{"issue":"10","key":"39_34356736","doi-asserted-by":"publisher","first-page":"1274","DOI":"10.1038\/ejhg.2009.38","volume":"17","author":"Chanda","year":"2009","journal-title":"European journal of human genetics : EJHG","ISSN":"https:\/\/id.crossref.org\/issn\/1018-4813","issn-type":"print"},{"issue":"5","key":"40_29596289","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1086\/521878","volume":"81","author":"Chanda","year":"2007","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"key":"41_24911185","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1002\/j.1538-7305.1948.tb01338.x","volume":"27","year":"1948","journal-title":"BELL SYST TECH J"},{"key":"43_39556143","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/02331880701529530","volume":"42","year":"2008","journal-title":"Statistics in medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0277-6715","issn-type":"print"},{"key":"45_39556144","first-page":"487","volume":"3","year":"2010","journal-title":"BMC genomics [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1471-2164","issn-type":"print"},{"issue":"4","key":"47_18769355","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1038\/ng1537","volume":"37","author":"Marchini","year":"2005","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"key":"48_39556145","first-page":"632","volume":"27","year":"2008","journal-title":"STAT IN MED"},{"issue":"10","key":"50_37281192","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1038\/ejhg.2010.48","volume":"18","author":"De Lobel","year":"2010","journal-title":"European journal of human genetics : EJHG","ISSN":"https:\/\/id.crossref.org\/issn\/1018-4813","issn-type":"print"},{"issue":"14","key":"51_37353835","doi-asserted-by":"publisher","first-page":"1752","DOI":"10.1093\/bioinformatics\/btq257","volume":"26","year":"2010","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"4","key":"52_32956056","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1093\/bioinformatics\/btn652","volume":"25","year":"2009","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"9","key":"53_29331415","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1038\/ng2110","volume":"39","author":"Zhang","year":"2007","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"key":"58_30592258","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1186\/1471-2105-9-146","volume":"9","author":"Mechanic","year":"2008","journal-title":"BMC bioinformatics [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1471-2105","issn-type":"print"},{"issue":"1","key":"59_11197196","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1086\/321276","volume":"69","author":"Ritchie","year":"2001","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"key":"60_39556146","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/3-540-45123-4_25","volume":"1848","year":"2000","journal-title":"COMBIN PATTERN MATCH"},{"issue":"2","key":"61_23622172","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1159\/000099181","volume":"63","author":"Culverhouse","year":"2007","journal-title":"Human heredity","ISSN":"https:\/\/id.crossref.org\/issn\/0001-5652","issn-type":"print"},{"key":"62_39556147","doi-asserted-by":"crossref","first-page":"S74","DOI":"10.1186\/1753-6561-3-s7-s74","volume":"3","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/1753-6561","issn-type":"print"},{"issue":"3","key":"63_19715959","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1159\/000089868","volume":"60","author":"Sun","year":"2005","journal-title":"Human heredity","ISSN":"https:\/\/id.crossref.org\/issn\/0001-5652","issn-type":"print"},{"issue":"2","key":"64_18614167","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1002\/gepi.20042","volume":"28","author":"Kooperberg","year":"2005","journal-title":"Genetic epidemiology","ISSN":"https:\/\/id.crossref.org\/issn\/0741-0395","issn-type":"print"},{"key":"65_33412254","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1198\/1061860032238","volume":"12","year":"2003","ISSN":"https:\/\/id.crossref.org\/issn\/1061-8600","issn-type":"print"},{"issue":"4","key":"66_23009333","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1159\/000096995","volume":"62","author":"Zheng","year":"2006","journal-title":"Human heredity","ISSN":"https:\/\/id.crossref.org\/issn\/0001-5652","issn-type":"print"},{"key":"67_38368619","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1186\/1471-2105-11-524","volume":"11","author":"Yang","year":"2010","journal-title":"BMC bioinformatics [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1471-2105","issn-type":"print"},{"issue":"17","key":"68_37616923","doi-asserted-by":"publisher","first-page":"2183","DOI":"10.1093\/bioinformatics\/btq354","volume":"26","year":"2010","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"2","key":"70_18614170","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1002\/gepi.20041","volume":"28","author":"Bureau","year":"2005","journal-title":"Genetic epidemiology","ISSN":"https:\/\/id.crossref.org\/issn\/0741-0395","issn-type":"print"},{"key":"71_36582266","doi-asserted-by":"crossref","first-page":"S65","DOI":"10.1186\/1471-2105-10-S1-S65","volume":"10","year":"2009","journal-title":"BMC bioinformatics [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1471-2105","issn-type":"print"},{"key":"72_18637098","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1186\/1471-2156-5-32","volume":"5","author":"Lunetta","year":"2004","journal-title":"BMC genetics [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1471-2156","issn-type":"print"},{"key":"73_39556148","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1016\/j.eswa.2007.01.029","volume":"34","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/0957-4174","issn-type":"print"},{"issue":"9","key":"75_35618764","doi-asserted-by":"publisher","first-page":"e7087","DOI":"10.1371\/journal.pone.0007087","volume":"4","author":"Karpievitch","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"issue":"17","key":"77_37534815","doi-asserted-by":"publisher","first-page":"2198","DOI":"10.1093\/bioinformatics\/btq352","volume":"26","year":"2010","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"key":"79_39556149","doi-asserted-by":"crossref","first-page":"S64","DOI":"10.1186\/1753-6561-3-s7-s64","volume":"3","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/1753-6561","issn-type":"print"},{"key":"80_35619331","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1186\/1471-2105-10-294","volume":"10","author":"Wongseree","year":"2009","journal-title":"BMC bioinformatics [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1471-2105","issn-type":"print"},{"key":"82_37396328","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1093\/genetics\/155.4.2003","volume":"155","year":"2000","ISSN":"https:\/\/id.crossref.org\/issn\/1943-2631","issn-type":"print"},{"issue":"8","key":"83_19664226","doi-asserted-by":"publisher","first-page":"1288","DOI":"10.1073\/pnas.45.8.1288","volume":"45","author":"Bellman","year":"1959","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"8","key":"84_30034511","doi-asserted-by":"publisher","first-page":"894","DOI":"10.1002\/gepi.20250","volume":"31","author":"Chapman","year":"2007","journal-title":"Genetic epidemiology","ISSN":"https:\/\/id.crossref.org\/issn\/0741-0395","issn-type":"print"},{"issue":"6","key":"85_23446662","doi-asserted-by":"publisher","first-page":"1002","DOI":"10.1086\/509704","volume":"79","author":"Chatterjee","year":"2006","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"issue":"2","key":"86_36346833","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1038\/nrg2600-c2","volume":"11","author":"Van de Peer","year":"2010","journal-title":"Nature reviews. Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1471-0056","issn-type":"print"},{"issue":"1","key":"87_36738041","doi-asserted-by":"crossref","first-page":"Article 1","DOI":"10.2202\/1544-6115.1517","volume":"9","author":"Vanderweele","year":"2010","ISSN":"https:\/\/id.crossref.org\/issn\/1544-6115","issn-type":"print"},{"key":"88_39556151","first-page":"146","volume":"75","year":"2010","journal-title":"Annals of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0003-4800","issn-type":"print"},{"key":"89_39556152","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1534\/genetics.109.111120","volume":"184","year":"2010","ISSN":"https:\/\/id.crossref.org\/issn\/1943-2631","issn-type":"print"},{"key":"90_22287030","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/1471-2156-7-39","volume":"7","author":"Ionita","year":"2006","journal-title":"BMC genetics [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1471-2156","issn-type":"print"},{"issue":"2","key":"91_18885964","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1159\/000085222","volume":"59","author":"North","year":"2005","journal-title":"Human heredity","ISSN":"https:\/\/id.crossref.org\/issn\/0001-5652","issn-type":"print"},{"key":"92_36216871","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1093\/biostatistics\/kxm010","volume":"9","year":"2007","journal-title":"Biostatistics","ISSN":"https:\/\/id.crossref.org\/issn\/1465-4644","issn-type":"print"},{"issue":"8","key":"93_23001658","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1002\/gepi.20176","volume":"30","author":"Tanck","year":"2006","journal-title":"Genetic epidemiology","ISSN":"https:\/\/id.crossref.org\/issn\/0741-0395","issn-type":"print"},{"issue":"9","key":"94_31451081","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1007\/s10038-008-0313-z","volume":"53","author":"Lin","year":"2008","journal-title":"Journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1434-5161","issn-type":"print"},{"issue":"1","key":"96_31520618","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1002\/gepi.20351","volume":"33","author":"Wang","year":"2009","journal-title":"Genetic epidemiology","ISSN":"https:\/\/id.crossref.org\/issn\/0741-0395","issn-type":"print"},{"issue":"3","key":"97_38090713","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/j.ajhg.2010.07.021","volume":"87","author":"Wan","year":"2010","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"key":"98_39556153","first-page":"S18","volume":"11","year":"2010","journal-title":"BMC bioinformatics [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1471-2105","issn-type":"print"},{"issue":"8","key":"99_38077294","doi-asserted-by":"publisher","first-page":"e11384","DOI":"10.1371\/journal.pone.0011384","volume":"5","author":"Wang","year":"2010","ISSN":"https:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"issue":"21","key":"100_11443595","doi-asserted-by":"publisher","first-page":"3215","DOI":"10.1002\/sim.976","volume":"20","author":"Viallefont","year":"2001","journal-title":"Statistics in medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0277-6715","issn-type":"print"},{"issue":"6","key":"102_18724892","doi-asserted-by":"publisher","first-page":"754","DOI":"10.1093\/bioinformatics\/bti062","volume":"21","year":"2005","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"4","key":"103_35311191","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1093\/biostatistics\/kxp025","volume":"10","year":"2009","journal-title":"Biostatistics","ISSN":"https:\/\/id.crossref.org\/issn\/1465-4644","issn-type":"print"},{"key":"104_34956138","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1186\/1752-0509-3-55","volume":"3","author":"Chu","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/1752-0509","issn-type":"print"},{"issue":"1","key":"105_38806979","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1111\/j.1469-1809.2010.00628.x","volume":"75","author":"Zwick","year":"2011","journal-title":"Annals of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0003-4800","issn-type":"print"},{"issue":"7265","key":"108_35714041","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1038\/nature08494","volume":"461","author":"Manolio","year":"2009","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"20","key":"109_17258504","doi-asserted-by":"publisher","first-page":"2463","DOI":"10.1093\/hmg\/11.20.2463","volume":"11","author":"Cordell","year":"2002","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"key":"110_39556154","first-page":"771","volume":"33","year":"2009","journal-title":"Genetic epidemiology","ISSN":"https:\/\/id.crossref.org\/issn\/0741-0395","issn-type":"print"},{"issue":"4","key":"111_37180974","doi-asserted-by":"publisher","first-page":"e10304","DOI":"10.1371\/journal.pone.0010304","volume":"5","author":"Cattaert","year":"2010","ISSN":"https:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"key":"112_36014407","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1534\/genetics.107.075614","volume":"177","year":"2007","ISSN":"https:\/\/id.crossref.org\/issn\/1943-2631","issn-type":"print"},{"issue":"3","key":"113_29258114","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1086\/519795","volume":"81","author":"Purcell","year":"2007","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"key":"114_35342054","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1186\/1756-0500-2-149","volume":"2","author":"Sinnott-Armstrong","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/1756-0500","issn-type":"print"},{"issue":"11","key":"115_37042362","doi-asserted-by":"publisher","first-page":"1468","DOI":"10.1093\/bioinformatics\/btq147","volume":"26","year":"2010","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"3","key":"118_37078943","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1089\/cmb.2009.0155","volume":"17","author":"Zhang","year":"2010","journal-title":"Journal of computational biology : a journal of computational molecular cell biology","ISSN":"https:\/\/id.crossref.org\/issn\/1066-5277","issn-type":"print"},{"issue":"12","key":"119_37396030","doi-asserted-by":"publisher","first-page":"i217","DOI":"10.1093\/bioinformatics\/btq186","volume":"26","year":"2010","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"5","key":"121_21888834","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1186\/1479-7364-2-5-310","volume":"2","author":"Dudbridge","year":"2006","journal-title":"Human genomics","ISSN":"https:\/\/id.crossref.org\/issn\/1473-9542","issn-type":"print"},{"issue":"6","key":"123_18205342","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1101\/gr.2156804","volume":"14","author":"Manly","year":"2004","journal-title":"Genome Research","ISSN":"https:\/\/id.crossref.org\/issn\/1088-9051","issn-type":"print"},{"key":"124_26523871","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.jspi.2003.07.019","volume":"125","year":"2004","journal-title":"J STAT PLANN INFERENCE"},{"issue":"4","key":"125_18089165","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1086\/383251","volume":"74","author":"Nyholt","year":"2004","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"issue":"6","key":"126_31721572","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1002\/gepi.20331","volume":"32","author":"Moskvina","year":"2008","journal-title":"Genetic epidemiology","ISSN":"https:\/\/id.crossref.org\/issn\/0741-0395","issn-type":"print"},{"key":"127_28970624","doi-asserted-by":"crossref","first-page":"S78","DOI":"10.1186\/1471-2156-6-S1-S78","volume":"6","year":"2005","journal-title":"BMC genetics [electronic resource]","ISSN":"https:\/\/id.crossref.org\/issn\/1471-2156","issn-type":"print"},{"key":"128_35825080","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1111\/j.1467-9868.2008.00694.x","volume":"71","year":"2009","journal-title":"J R STAT SOC B"},{"issue":"21","key":"129_35370984","doi-asserted-by":"publisher","first-page":"2802","DOI":"10.1093\/bioinformatics\/btp476","volume":"25","year":"2009","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"7","key":"130_33875703","doi-asserted-by":"publisher","first-page":"964","DOI":"10.1093\/bioinformatics\/btp021","volume":"25","year":"2009","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"12","key":"131_30957068","doi-asserted-by":"publisher","first-page":"1461","DOI":"10.1093\/bioinformatics\/btn209","volume":"24","year":"2008","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"key":"132_24751994","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1111\/1467-9868.00346","volume":"64","year":"2002","journal-title":"J R STAT SOC B"},{"key":"133_34013428","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1214\/aos\/1074290335","volume":"31","year":"2003","ISSN":"https:\/\/id.crossref.org\/issn\/0090-5364","issn-type":"print"},{"issue":"22","key":"134_20366488","doi-asserted-by":"publisher","first-page":"1722","DOI":"10.1093\/jnci\/djh327","volume":"96","author":"Wacholder","year":"2004","journal-title":"JNCI Journal of the National Cancer Institute","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8874","issn-type":"print"},{"issue":"6","key":"135_18091940","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1093\/jnci\/djh075","volume":"96","author":"Wacholder","year":"2004","journal-title":"JNCI Journal of the National Cancer Institute","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8874","issn-type":"print"},{"key":"136_24706098","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1198\/016214501753382129","volume":"96","year":"2001","ISSN":"https:\/\/id.crossref.org\/issn\/0162-1459","issn-type":"print"},{"issue":"7","key":"139_23584955","doi-asserted-by":"publisher","first-page":"850","DOI":"10.1093\/bioinformatics\/btm019","volume":"23","year":"2007","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"key":"140_39556155","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1002\/bimj.200800203","volume":"51","year":"2009","journal-title":"BIOMETRICAL J"},{"issue":"R2","key":"141_32163385","doi-asserted-by":"publisher","first-page":"R122","DOI":"10.1093\/hmg\/ddn288","volume":"17","year":"2008","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"key":"144_34931448","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/j.0006-341X.2000.00052.x","volume":"56","year":"2000","ISSN":"https:\/\/id.crossref.org\/issn\/1541-0420","issn-type":"print"},{"key":"145_35762349","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1093\/genetics\/138.3.963","volume":"138","year":"1994","ISSN":"https:\/\/id.crossref.org\/issn\/1943-2631","issn-type":"print"},{"key":"146_36027063","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1093\/genetics\/142.1.285","volume":"142","year":"1996","ISSN":"https:\/\/id.crossref.org\/issn\/1943-2631","issn-type":"print"},{"issue":"2","key":"147_17109419","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1017\/S001667230200558X","volume":"79","author":"Carlborg","year":"2002","journal-title":"Genetical research","ISSN":"https:\/\/id.crossref.org\/issn\/0016-6723","issn-type":"print"},{"issue":"3","key":"148_18277190","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1086\/423738","volume":"75","author":"Dudbridge","year":"2004","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"issue":"12","key":"149_34931241","doi-asserted-by":"publisher","first-page":"i161","DOI":"10.1093\/bioinformatics\/btp211","volume":"25","year":"2009","journal-title":"Bioinformatics","ISSN":"https:\/\/id.crossref.org\/issn\/1367-4803","issn-type":"print"},{"issue":"1","key":"150_31639690","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1002\/gepi.20360","volume":"33","author":"Pattin","year":"2009","journal-title":"Genetic epidemiology","ISSN":"https:\/\/id.crossref.org\/issn\/0741-0395","issn-type":"print"},{"issue":"4","key":"151_34660160","doi-asserted-by":"publisher","first-page":"e1000456","DOI":"10.1371\/journal.pgen.1000456","volume":"5","author":"Han","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/1553-7390","issn-type":"print"},{"issue":"6","key":"152_33415973","doi-asserted-by":"publisher","first-page":"1158","DOI":"10.1086\/522036","volume":"81","author":"Conneely","year":"2007","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"key":"153_39556156","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1109\/5.784219","volume":"87","year":"1999","journal-title":"IEEE"},{"issue":"1","key":"154_38209230","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/1756-0381-3-5","volume":"3","author":"Turner","year":"2010","ISSN":"https:\/\/id.crossref.org\/issn\/1756-0381","issn-type":"print"},{"issue":"3","key":"155_30749721","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1002\/gepi.20300","volume":"32","author":"Kooperberg","year":"2008","journal-title":"Genetic epidemiology","ISSN":"https:\/\/id.crossref.org\/issn\/0741-0395","issn-type":"print"},{"issue":"6","key":"156_22397973","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1038\/ng1816","volume":"38","author":"Pe'er","year":"2006","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"5","key":"157_36348881","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1038\/ejhg.2009.223","volume":"18","author":"Peng","year":"2010","journal-title":"European journal of human genetics : EJHG","ISSN":"https:\/\/id.crossref.org\/issn\/1018-4813","issn-type":"print"},{"issue":"11","key":"158_36110054","doi-asserted-by":"publisher","first-page":"e8064","DOI":"10.1371\/journal.pone.0008064","volume":"4","author":"Zhang","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/1932-6203","issn-type":"print"},{"key":"159_39556157","first-page":"368","volume":"14","year":"2009","journal-title":"Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing","ISSN":"https:\/\/id.crossref.org\/issn\/1793-5091","issn-type":"print"},{"key":"160_39556158","first-page":"123","volume":"19","year":"2010","journal-title":"European journal of human genetics : EJHG","ISSN":"https:\/\/id.crossref.org\/issn\/1018-4813","issn-type":"print"},{"issue":"2","key":"161_22523617","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1016\/j.jtbi.2005.11.036","volume":"241","author":"Moore","year":"2006","journal-title":"Journal of Theoretical Biology","ISSN":"https:\/\/id.crossref.org\/issn\/1095-8541","issn-type":"print"},{"issue":"5","key":"162_22807709","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1086\/508571","volume":"79","author":"Zhao","year":"2006","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"key":"163_36034284","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1093\/genetics\/39.6.859","volume":"39","year":"1954","ISSN":"https:\/\/id.crossref.org\/issn\/1943-2631","issn-type":"print"},{"issue":"4","key":"164_16041670","first-page":"920","volume":"57","author":"Cordell","year":"1995","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"issue":"6","key":"165_17938015","doi-asserted-by":"publisher","first-page":"1467","DOI":"10.1086\/380310","volume":"73","author":"Farrall","year":"2003","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"issue":"1","key":"166_32313413","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1159\/000164395","volume":"67","author":"Zhang","year":"2009","journal-title":"Human heredity","ISSN":"https:\/\/id.crossref.org\/issn\/0001-5652","issn-type":"print"},{"issue":"1","key":"167_36601200","doi-asserted-by":"publisher","first-page":"e1000293","DOI":"10.1371\/journal.pbio.1000293","volume":"8","author":"Robinson","year":"2010","journal-title":"PLoS biology","ISSN":"https:\/\/id.crossref.org\/issn\/1544-9173","issn-type":"print"},{"issue":"6","key":"168_37318174","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1038\/nrg2809","volume":"11","author":"Eichler","year":"2010","journal-title":"Nature reviews. Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1471-0056","issn-type":"print"},{"issue":"6","key":"169_31221555","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1038\/ng.f.136","volume":"40","author":"Bodmer","year":"2008","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"1","key":"170_36601201","doi-asserted-by":"publisher","first-page":"e1000294","DOI":"10.1371\/journal.pbio.1000294","volume":"8","author":"Dickson","year":"2010","journal-title":"PLoS biology","ISSN":"https:\/\/id.crossref.org\/issn\/1544-9173","issn-type":"print"},{"issue":"8","key":"171_19442747","doi-asserted-by":"publisher","first-page":"1029","DOI":"10.1074\/mcp.M500024-MCP200","volume":"4","year":"2005","journal-title":"Molecular & Cellular Proteomics","ISSN":"https:\/\/id.crossref.org\/issn\/1535-9476","issn-type":"print"},{"issue":"10","key":"173_38398918","doi-asserted-by":"publisher","first-page":"e1001156","DOI":"10.1371\/journal.pgen.1001156","volume":"6","author":"Liu","year":"2010","ISSN":"https:\/\/id.crossref.org\/issn\/1553-7390","issn-type":"print"},{"issue":"2","key":"174_34056649","doi-asserted-by":"publisher","first-page":"e1000384","DOI":"10.1371\/journal.pgen.1000384","volume":"5","author":"Madsen","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/1553-7390","issn-type":"print"},{"issue":"3","key":"175_31700905","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1016\/j.ajhg.2008.06.024","volume":"83","author":"Li","year":"2008","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"key":"176_35618978","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1007\/978-1-60761-247-6_17","volume":"573","author":"Franke","year":"2009","journal-title":"Methods in molecular biology (Clifton, N.J.)","ISSN":"https:\/\/id.crossref.org\/issn\/1064-3745","issn-type":"print"},{"issue":"6","key":"177_35224906","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1186\/gm65","volume":"1","author":"Ritchie","year":"2009","ISSN":"https:\/\/id.crossref.org\/issn\/1756-994X","issn-type":"print"},{"issue":"3","key":"178_18735442","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1158\/1055-9965.EPI-14-3-EDB","volume":"14","author":"Thomas","year":"2005","journal-title":"Cancer Epidemiology Biomarkers & Prevention","ISSN":"https:\/\/id.crossref.org\/issn\/1055-9965","issn-type":"print"},{"issue":"1","key":"179_30224354","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1007\/s00439-008-0522-8","volume":"124","author":"Eiberg","year":"2008","journal-title":"Human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0340-6717","issn-type":"print"},{"issue":"11","key":"180_34279078","doi-asserted-by":"publisher","first-page":"2078","DOI":"10.1093\/hmg\/ddp120","volume":"18","year":"2009","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"8","key":"181_37419572","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1101\/gr.102749.109","volume":"20","year":"2010","journal-title":"Genome Research","ISSN":"https:\/\/id.crossref.org\/issn\/1088-9051","issn-type":"print"},{"issue":"5","key":"182_18844664","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1038\/nbt1096","volume":"23","author":"Kelley","year":"2005","journal-title":"Nature biotechnology","ISSN":"https:\/\/id.crossref.org\/issn\/1087-0156","issn-type":"print"},{"issue":"8","key":"183_37359943","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.1101\/gr.104216.109","volume":"20","year":"2010","journal-title":"Genome Research","ISSN":"https:\/\/id.crossref.org\/issn\/1088-9051","issn-type":"print"},{"issue":"3","key":"184_35559510","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.ajhg.2009.08.006","volume":"85","author":"Moore","year":"2009","journal-title":"American journal of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9297","issn-type":"print"},{"issue":"5","key":"187_16933688","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1093\/aje\/155.5.478","volume":"155","author":"Gauderman","year":"2002","journal-title":"American Journal of Epidemiology","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9262","issn-type":"print"},{"issue":"Pt 5","key":"188_29115890","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1111\/j.1469-1809.2007.00360.x","volume":"71","author":"Vermeulen","year":"2007","journal-title":"Annals of human genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0003-4800","issn-type":"print"},{"issue":"6","key":"189_31101427","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1093\/carcin\/bgn120","volume":"29","year":"2008","journal-title":"Carcinogenesis","ISSN":"https:\/\/id.crossref.org\/issn\/0143-3334","issn-type":"print"},{"issue":"8","key":"190_17745642","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1038\/sj.ejhg.5201008","volume":"11","author":"B\u00a0\u00a0hringer","year":"2003","journal-title":"European journal of human genetics : EJHG","ISSN":"https:\/\/id.crossref.org\/issn\/1018-4813","issn-type":"print"}],"container-title":["Briefings in Bioinformatics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/bib\/article-pdf\/13\/1\/1\/582310\/bbr012.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T13:18:14Z","timestamp":1712323094000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bib\/article-lookup\/doi\/10.1093\/bib\/bbr012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,26]]},"references-count":157,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2012,1,5]]},"published-print":{"date-parts":[[2012,1,1]]}},"URL":"https:\/\/doi.org\/10.1093\/bib\/bbr012","relation":{},"ISSN":["1467-5463","1477-4054"],"issn-type":[{"value":"1467-5463","type":"print"},{"value":"1477-4054","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,26]]}}}