{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T09:12:19Z","timestamp":1778058739600,"version":"3.51.4"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"22-23","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Italian Ministero dell\u2019Universit\u00e0 e Ricerca","award":["PRIN 2017"],"award-info":[{"award-number":["PRIN 2017"]}]},{"DOI":"10.13039\/501100004462","name":"Consiglio Nazionale delle Ricerche","doi-asserted-by":"publisher","award":["GA: 824087"],"award-info":[{"award-number":["GA: 824087"]}],"id":[{"id":"10.13039\/501100004462","id-type":"DOI","asserted-by":"publisher"}]},{"name":"EOSC-Pillar","award":["GA: 857650"],"award-info":[{"award-number":["GA: 857650"]}]},{"name":"ELIXIR Converge","award":["GA: 871075"],"award-info":[{"award-number":["GA: 871075"]}]},{"name":"Elixir-IIB"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Summary<\/jats:title>\n                  <jats:p>While over 200 000 genomic sequences are currently available through dedicated repositories, ad hoc methods for the functional annotation of SARS-CoV-2 genomes do not harness all currently available resources for the annotation of functionally relevant genomic sites. Here, we present CorGAT, a novel tool for the functional annotation of SARS-CoV-2 genomic variants. By comparisons with other state of the art methods we demonstrate that, by providing a more comprehensive and rich annotation, our method can facilitate the identification of evolutionary patterns in the genome of SARS-CoV-2.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Availabilityand implementation<\/jats:title>\n                  <jats:p>Galaxy<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>\u2002<\/jats:title>\n                  <jats:p>http:\/\/corgat.cloud.ba.infn.it\/galaxy; software: https:\/\/github.com\/matteo14c\/CorGAT\/tree\/Revision_V1; docker: https:\/\/hub.docker.com\/r\/laniakeacloud\/galaxy_corgat.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Supplementary information<\/jats:title>\n                  <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btaa1047","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T04:10:01Z","timestamp":1607573401000},"page":"5522-5523","source":"Crossref","is-referenced-by-count":9,"title":["CorGAT: a tool for the functional annotation of SARS-CoV-2 genomes"],"prefix":"10.1093","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3983-4961","authenticated-orcid":false,"given":"Matteo","family":"Chiara","sequence":"first","affiliation":[{"name":"Department of Biosciences, University of Milan , 20133 Milan, Italy"},{"name":"Institute of Biomembranes, Bioenergetics and Molecular Biotechnology, National Research Council , 70126 Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Zambelli","sequence":"additional","affiliation":[{"name":"Department of Biosciences, University of Milan , 20133 Milan, Italy"},{"name":"Institute of Biomembranes, Bioenergetics and Molecular Biotechnology, National Research Council , 70126 Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco Antonio","family":"Tangaro","sequence":"additional","affiliation":[{"name":"Institute of Biomembranes, Bioenergetics and Molecular Biotechnology, National Research Council , 70126 Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Mandreoli","sequence":"additional","affiliation":[{"name":"Department of Biosciences, University of Milan , 20133 Milan, Italy"},{"name":"Institute of Biomembranes, Bioenergetics and Molecular Biotechnology, National Research Council , 70126 Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David S","family":"Horner","sequence":"additional","affiliation":[{"name":"Department of Biosciences, University of Milan , 20133 Milan, Italy"},{"name":"Institute of Biomembranes, Bioenergetics and Molecular Biotechnology, National Research Council , 70126 Bari, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3663-0859","authenticated-orcid":false,"given":"Graziano","family":"Pesole","sequence":"additional","affiliation":[{"name":"Institute of Biomembranes, Bioenergetics and Molecular Biotechnology, National Research Council , 70126 Bari, Italy"},{"name":"Department of Biosciences, Biotechnology and Biopharmaceutics, University of Bari \u201cA. 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