{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T04:12:44Z","timestamp":1780373564188,"version":"3.54.1"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2020,2,25]],"date-time":"2020-02-25T00:00:00Z","timestamp":1582588800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Spanish Ministerio de Ciencia"},{"name":"Innovaci\u00f3n y Universidades","award":["SAF2015-74627-JIN"],"award-info":[{"award-number":["SAF2015-74627-JIN"]}]},{"name":"Innovaci\u00f3n y Universidades","award":["SAF2016-77830-R"],"award-info":[{"award-number":["SAF2016-77830-R"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Motivation<\/jats:title>\n                    <jats:p>G protein-coupled receptors (GPCRs) can form homo-, heterodimers and larger order oligomers that exert different functions than monomers. The pharmacological potential of such complexes is hampered by the limited information available on the type of complex formed and its quaternary structure. Several GPCR structures in the Protein Data Bank display crystallographic interfaces potentially compatible with physiological interactions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Here, we present DIMERBOW, a database and web application aimed to visually browse the complete repertoire of potential GPCR dimers present in solved structures. The tool is suited to help finding the best possible structural template to model GPCR homomers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Availability and implementation<\/jats:title>\n                    <jats:p>DIMERBOW is available at http:\/\/lmc.uab.es\/dimerbow\/.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Supplementary information<\/jats:title>\n                    <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btaa117","type":"journal-article","created":{"date-parts":[[2020,2,18]],"date-time":"2020-02-18T07:16:22Z","timestamp":1582010182000},"page":"3271-3272","source":"Crossref","is-referenced-by-count":12,"title":["DIMERBOW: exploring possible GPCR dimer interfaces"],"prefix":"10.1093","volume":"36","author":[{"given":"Adri\u00e1n","family":"Garc\u00eda-Recio","sequence":"first","affiliation":[{"name":"Laboratori de Medicina Computacional , Unitat de Bioestadistica, Facultat de Medicina, Universitat Aut\u00f2noma de Barcelona, Bellaterra 08193, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gemma","family":"Navarro","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Physiology , Universitat de Barcelona, Barcelona, Spain"},{"name":"CiberNed , Centro De Investigacion En Red, Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Franco","sequence":"additional","affiliation":[{"name":"CiberNed , Centro De Investigacion En Red, Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain"},{"name":"Department of Biochemistry and Molecular Biomedicine , Faculty of Biology, Universitat de Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6035-3399","authenticated-orcid":false,"given":"Mireia","family":"Olivella","sequence":"additional","affiliation":[{"name":"Bioinformatics and Medical Statistics Group , Biosciences Department, University of Vic-Central University of Catalonia, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramon","family":"Guix\u00e0-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Laboratori de Medicina Computacional , Unitat de Bioestadistica, Facultat de Medicina, Universitat Aut\u00f2noma de Barcelona, Bellaterra 08193, Spain"},{"name":"Laboratory of Biomolecular Research"},{"name":"Condensed Matter Theory Group , Paul Scherrer Institute (PSI), Villigen PSI 5232, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnau","family":"Cordom\u00ed","sequence":"additional","affiliation":[{"name":"Laboratori de Medicina Computacional , Unitat de Bioestadistica, Facultat de Medicina, Universitat Aut\u00f2noma de Barcelona, Bellaterra 08193, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,2,25]]},"reference":[{"key":"2023013112032833200_btaa117-B1","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.softx.2015.06.001","article-title":"GROMACS: high performance molecular simulations through multi-level parallelism from laptops to supercomputers","volume":"1\u20132","author":"Abraham","year":"2015","journal-title":"SoftwareX"},{"key":"2023013112032833200_btaa117-B2","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1007\/s10822-016-9919-y","article-title":"Molecular dynamics simulations and structure-based network analysis reveal structural and functional aspects of G-protein coupled receptor dimer interactions","volume":"30","author":"Baltoumas","year":"2016","journal-title":"J. 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