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It is characterized by an unsupervised read clustering step, based on Uniform Manifold Approximation and Projection (UMAP), followed by the construction of a polished read and subsequent Blast classification. Here, we demonstrate that NanoCLUST performs better than other state-of-the-art software in the characterization of two commercial mock communities, enabling accurate bacterial identification and abundance profile estimation at species-level resolution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Availability and implementation<\/jats:title>\n                    <jats:p>Source code, test data and documentation of NanoCLUST are freely available at https:\/\/github.com\/genomicsITER\/NanoCLUST under MIT License.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Supplementary information<\/jats:title>\n                    <jats:p>Supplementary data are available at Bioinformatics online.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/bioinformatics\/btaa900","type":"journal-article","created":{"date-parts":[[2020,10,5]],"date-time":"2020-10-05T15:15:57Z","timestamp":1601910957000},"page":"1600-1601","source":"Crossref","is-referenced-by-count":124,"title":["NanoCLUST: a species-level analysis of 16S rRNA nanopore sequencing data"],"prefix":"10.1093","volume":"37","author":[{"given":"H\u00e9ctor","family":"Rodr\u00edguez-P\u00e9rez","sequence":"first","affiliation":[{"name":"Research Unit, Hospital Universitario Nuestra Se\u00f1ora de Candelaria, Universidad de La Laguna , Santa Cruz de Tenerife, 38010, Spain"}]},{"given":"Laura","family":"Ciuffreda","sequence":"additional","affiliation":[{"name":"Research Unit, Hospital Universitario Nuestra Se\u00f1ora de Candelaria, Universidad de La Laguna , Santa Cruz de Tenerife, 38010, Spain"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5352-069X","authenticated-orcid":false,"given":"Carlos","family":"Flores","sequence":"additional","affiliation":[{"name":"Research Unit, Hospital Universitario Nuestra Se\u00f1ora de Candelaria, Universidad de La Laguna , Santa Cruz de Tenerife, 38010, Spain"},{"name":"Instituto de Salud Carlos III, CIBER de Enfermedades Respiratorias , Madrid, 28029, Spain"},{"name":"Genomics Division, Instituto Tecnol\u00f3gico y de Energ\u00edas Renovables (ITER), 38600 Granadilla , Santa Cruz de Tenerife, Spain"},{"name":"Instituto de Tecnolog\u00edas Biom\u00e9dicas (ITB), Universidad de La Laguna, 38200 San Crist\u00f3bal de La Laguna , Santa Cruz de Tenerife, Spain"}]}],"member":"286","published-online":{"date-parts":[[2020,10,18]]},"reference":[{"key":"2023051709444449000_btaa900-B1","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1101\/gr.251686.119","article-title":"Assembly-free single-molecule sequencing recovers complete virus genomes from natural microbial communities","volume":"30","author":"Beaulaurier","year":"2020","journal-title":"Genome Res"},{"key":"2023051709444449000_btaa900-B2","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1038\/nmeth.f.303","article-title":"QIIME allows analysis of high-throughput community sequencing data","volume":"7","author":"Caporaso","year":"2010","journal-title":"Nat. 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